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The VAA in the range of one papillary diameter (PD) as well as 2PD away from the central point of optic disc was recognized and measured by artificial intelligence from fundus photographs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Finally, 277 highly myopic participants were included in the analysis. The mean VAA (1PD) was 128.38\u2009\u00b1\u20099.56\u00b0, and the mean VAA (2PD) was 110.25\u2009\u00b1\u200911.97\u00b0. For those with larger VAA, the choroidal thickness around macula (mChT) or papillary (pChT) was thicker (P for trend &lt;\u20090.05). After adjusting for age and gender, thinner ChT was independently associated with smaller VAA (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). For those with more decrease of VAA, the thinning of ChT was more remarkable (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05). In the regression analysis, more change of pChT was independently associated with more change of VAA (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.01). After adjusting for other related parameters, 1\u00b0change of VAA (1PD) or VAA (2PD) accounted for 0.855\u2009mm or 0.719\u2009mm change of pChT.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Fundus VAA was closely associated with choroidal thickness in highly myopic paediatric population. It could serve as an alternative indicator of choroid thickness in the fundus screening for evaluating the risk of pathological changes of high myopia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1038\/s41433-025-03604-9","type":"journal-article","created":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T10:59:15Z","timestamp":1737197955000},"page":"1264-1269","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Fundus vascular arcades angle reflects choroidal thickness in highly myopic children and adolescents"],"prefix":"10.1038","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8496-5288","authenticated-orcid":false,"given":"Wei","family":"Gong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dengji","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saiguang","family":"Ling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinliuxing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4246-4343","authenticated-orcid":false,"given":"Xun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8938-1879","authenticated-orcid":false,"given":"Xiangui","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5005-7801","authenticated-orcid":false,"given":"Wei","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,18]]},"reference":[{"key":"3604_CR1","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1038\/s41572-020-00231-4","volume":"6","author":"PN Baird","year":"2020","unstructured":"Baird PN, Saw SM, Lanca C, Guggenheim JA, Smith Iii EL, Zhou X, et al. 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