{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T01:19:06Z","timestamp":1718414346885},"reference-count":71,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T00:00:00Z","timestamp":1537488000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hypertens Res"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1038\/s41440-018-0104-7","type":"journal-article","created":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T13:11:58Z","timestamp":1537535518000},"page":"1000-1012","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Carotid body removal normalizes arterial blood pressure and respiratory frequency in offspring of protein-restricted mothers"],"prefix":"10.1038","volume":"41","author":[{"given":"Viviane","family":"Nogueira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose","family":"Brito-Alves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danilo","family":"Fontes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larissa","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waldecy","family":"Lucca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves","family":"Tourneur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Almir","family":"Wanderley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glauber S. F.","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carol","family":"Leandro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Henrique","family":"Costa-Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,9,21]]},"reference":[{"key":"104_CR1","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.numecd.2014.07.011","volume":"25","author":"MA Barros","year":"2015","unstructured":"Barros MA, De Brito Alves JL, Nogueira VO, Wanderley AG, Costa-Silva JH. Maternal low-protein diet induces changes in the cardiovascular autonomic modulation in male rat offspring. Nutr Metab Cardiovasc Dis. 2015;25:123\u201330.","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"104_CR2","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1017\/S0007114513002833","volume":"111","author":"JL Brito Alves de","year":"2014","unstructured":"de Brito Alves JL, Nogueira VO, de Oliveira GB, da Silva GS, Wanderley AG, Leandro CG, et al. Short- and long-term effects of a maternal low-protein diet on ventilation, O(2)\/CO(2) chemoreception and arterial blood pressure in male rat offspring. Br J Nutr. 2014;111:606\u201315.","journal-title":"Br J Nutr"},{"key":"104_CR3","doi-asserted-by":"publisher","first-page":"448","DOI":"10.3389\/fphys.2016.00448","volume":"7","author":"JL Brito Alves de","year":"2016","unstructured":"de Brito Alves JL, de Sousa VP, Cavalcanti Neto MP, Magnani M, Braga VA, da Costa-Silva JH, et al. New insights on the use of dietary polyphenols or probiotics for the management of arterial hypertension. Front Physiol. 2016;7:448.","journal-title":"Front Physiol"},{"key":"104_CR4","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1016\/0140-6736(93)91224-A","volume":"341","author":"DJ Barker","year":"1993","unstructured":"Barker DJ, Gluckman PD, Godfrey KM, Harding JE, Owens JA, Robinson JS. Fetal nutrition and cardiovascular disease in adult life. Lancet. 1993;341:938\u201341.","journal-title":"Lancet"},{"key":"104_CR5","doi-asserted-by":"publisher","first-page":"504","DOI":"10.3389\/fphys.2016.00504","volume":"7","author":"JH Costa-Silva","year":"2016","unstructured":"Costa-Silva JH, Simoes-Alves AC, Fernandes MP. Developmental origins of cardiometabolic diseases: role of the maternal diet. Front Physiol. 2016;7:504.","journal-title":"Front Physiol"},{"issue":"5","key":"104_CR6","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1111\/1440-1681.12892","volume":"45","author":"Jos\u00e9 Luiz de Brito Alves","year":"2017","unstructured":"de Brito Alves JL, Costa-Silva JH. Maternal protein malnutrition induced-hypertension: new evidence about the autonomic and respiratory dysfunctions and epigenetic mechanisms. Clin Exp Pharmacol Physiol. 2017;45:422\u20139.","journal-title":"Clinical and Experimental Pharmacology and Physiology"},{"key":"104_CR7","doi-asserted-by":"crossref","unstructured":"Brito-Alves JL, Nogueira, VO, Cavalcanti-Neto, MP, Leopoldino, MA, Curti, C, Colombari, DSA, et al. Maternal protein restriction increases respiratory and sympathetic activities and sensitizes peripheral chemoreflex in male rat offspring. J Nutr. 2015;145:907\u201314.","DOI":"10.3945\/jn.114.202804"},{"key":"104_CR8","doi-asserted-by":"publisher","first-page":"345","DOI":"10.3389\/fphys.2015.00345","volume":"6","author":"JH Costa-Silva","year":"2015","unstructured":"Costa-Silva JH, de Brito-Alves JL, Barros MA, Nogueira VO, Paulino-Silva KM, de Oliveira-Lira A, et al. New insights on the maternal diet induced-hypertension: potential role of the phenotypic plasticity and sympathetic-respiratory overactivity. Front Physiol. 2015;6:345.","journal-title":"Front Physiol"},{"key":"104_CR9","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1111\/1440-1681.12628","volume":"43","author":"KM Paulino-Silva","year":"2016","unstructured":"Paulino-Silva KM, Costa-Silva JH. Hypertension in rat offspring subjected to perinatal protein malnutrition is not related to the baroreflex dysfunction. Clin Exp Pharmacol & Physiol. 2016;43:1046\u201353.","journal-title":"Clin Exp Pharmacol & Physiol"},{"key":"104_CR10","doi-asserted-by":"publisher","first-page":"11480","DOI":"10.1021\/ic401782x","volume":"52","author":"ES Elton","year":"2013","unstructured":"Elton ES, Zhang T, Prabhakar R, Arif AM, Berreau LM. Pb(II)-promoted amide cleavage: mechanistic comparison to a Zn(II) analogue. Inorg Chem. 2013;52:11480\u201392.","journal-title":"Inorg Chem"},{"issue":"Pt 2","key":"104_CR11","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1113\/jphysiol.2005.103788","volume":"572","author":"AC Takakura","year":"2006","unstructured":"Takakura AC, Moreira TS, Colombari E, West GH, Stornetta RL, Guyenet PG. Peripheral chemoreceptor inputs to retrotrapezoid nucleus (RTN) CO2-sensitive neurons in rats. J Physiol. 2006;572(Pt 2):503\u201323.","journal-title":"J Physiol"},{"key":"104_CR12","doi-asserted-by":"publisher","first-page":"3371","DOI":"10.1113\/JP272046","volume":"594","author":"TM Basting","year":"2016","unstructured":"Basting TM, Abe C, Viar KE, Stornetta RL, Guyenet PG. Is plasticity within the retrotrapezoid nucleus responsible for the recovery of the PCO2 set-point after carotid body denervation in rats? J Physiol. 2016;594:3371\u201390.","journal-title":"J Physiol"},{"key":"104_CR13","doi-asserted-by":"publisher","first-page":"1511","DOI":"10.1002\/cphy.c140004","volume":"4","author":"PG Guyenet","year":"2014","unstructured":"Guyenet PG. Regulation of breathing and autonomic outflows by chemoreceptors. Compr Physiol. 2014;4:1511\u201362.","journal-title":"Compr Physiol"},{"key":"104_CR14","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.brainres.2012.10.028","volume":"1511","author":"PG Guyenet","year":"2013","unstructured":"Guyenet PG, Abbott SB, Stornetta RL. The respiratory chemoreception conundrum: light at the end of the tunnel? Brain Res. 2013;1511:126\u201337.","journal-title":"Brain Res"},{"key":"104_CR15","doi-asserted-by":"publisher","first-page":"12466","DOI":"10.1523\/JNEUROSCI.3141-10.2010","volume":"30","author":"N Marina","year":"2010","unstructured":"Marina N, Abdala AP, Trapp S, Li A, Nattie EE, Hewinson J, et al. Essential role of Phox2b-expressing ventrolateral brainstem neurons in the chemosensory control of inspiration and expiration. J Neurosci. 2010;30:12466\u201373.","journal-title":"J Neurosci"},{"key":"104_CR16","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1152\/physrev.1994.74.4.829","volume":"74","author":"C Gonzalez","year":"1994","unstructured":"Gonzalez C, Almaraz L, Obeso A, Rigual R. Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol Rev. 1994;74:829\u201398.","journal-title":"Physiol Rev"},{"key":"104_CR17","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1146\/annurev.neuro.26.041002.131103","volume":"26","author":"JL Feldman","year":"2003","unstructured":"Feldman JL, Mitchell GS, Nattie EE. Breathing: rhythmicity, plasticity, chemosensitivity. Annu Rev Neurosci. 2003;26:239\u201366.","journal-title":"Annu Rev Neurosci"},{"key":"104_CR18","doi-asserted-by":"publisher","first-page":"3253","DOI":"10.1113\/jphysiol.2008.154187","volume":"586","author":"DB Zoccal","year":"2008","unstructured":"Zoccal DB, Simms AE, Bonagamba LG, Braga VA, Pickering AE, Paton JF, et al. Increased sympathetic outflow in juvenile rats submitted to chronic intermittent hypoxia correlates with enhanced expiratory activity. J Physiol. 2008;586:3253\u201365.","journal-title":"J Physiol"},{"key":"104_CR19","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1007\/s00394-009-0032-z","volume":"48","author":"JH Costa-Silva","year":"2009","unstructured":"Costa-Silva JH, Silva PA, Pedi N, Luzardo R, Einicker-Lamas M, Lara LS, et al. Chronic undernutrition alters renal active Na\u2009+\u2009transport in young rats: potential hidden basis for pathophysiological alterations in adulthood? Eur J Nutr. 2009;48:437\u201345.","journal-title":"Eur J Nutr"},{"key":"104_CR20","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1002\/cphy.c140039","volume":"5","author":"NR Prabhakar","year":"2015","unstructured":"Prabhakar NR, Peng YJ, Kumar GK, Nanduri J. Peripheral chemoreception and arterial pressure responses to intermittent hypoxia. Compr Physiol. 2015;5:561\u201377.","journal-title":"Compr Physiol"},{"key":"104_CR21","doi-asserted-by":"publisher","first-page":"468","DOI":"10.3389\/fphys.2014.00468","volume":"5","author":"R Iturriaga","year":"2014","unstructured":"Iturriaga R, Andrade DC, Del Rio R. Enhanced carotid body chemosensory activity and the cardiovascular alterations induced by intermittent hypoxia. Front Physiol. 2014;5:468.","journal-title":"Front Physiol"},{"key":"104_CR22","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1007\/s00424-011-0990-x","volume":"462","author":"GS Silva da","year":"2011","unstructured":"da Silva GS, Giusti H, Benedetti M, Dias MB, Gargaglioni LH, Branco LG, et al. Serotonergic neurons in the nucleus raphe obscurus contribute to interaction between central and peripheral ventilatory responses to hypercapnia. Pflugers Arch. 2011;462:407\u201318.","journal-title":"Pflugers Arch"},{"key":"104_CR23","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms3395","volume":"4","author":"FD McBryde","year":"2013","unstructured":"McBryde FD, Abdala AP, Hendy EB, Pijacka W, Marvar P, Moraes DJ, et al. The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension. Nat Commun. 2013;4:2395.","journal-title":"Nat Commun"},{"issue":"Pt 2","key":"104_CR24","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1113\/jphysiol.2013.266221","volume":"592","author":"NJ Marcus","year":"2014","unstructured":"Marcus NJ, Del Rio R, Schultz EP, Xia XH, Schultz HD. Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure. J Physiol. 2014;592(Pt 2):391\u2013408.","journal-title":"J Physiol"},{"key":"104_CR25","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.jacbts.2016.06.004","volume":"1","author":"K Narkiewicz","year":"2016","unstructured":"Narkiewicz K, Ratcliffe LE, Hart EC, Briant LJ, Chrostowska M, Wolf J, et al. Unilateral carotid body resection in resistant hypertension: a safety and feasibility trial. JACC Basic Transl Sci. 2016;1:313\u201324.","journal-title":"JACC Basic Transl Sci"},{"key":"104_CR26","doi-asserted-by":"publisher","first-page":"1939","DOI":"10.1093\/jn\/123.11.1939","volume":"123","author":"PG Reeves","year":"1993","unstructured":"Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr. 1993;123:1939\u201351.","journal-title":"J Nutr"},{"key":"104_CR27","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/0034-5687(70)90056-3","volume":"10","author":"D Bartlett Jr","year":"1970","unstructured":"Bartlett D Jr, Tenney SM. Control of breathing in experimental anemia. Respir Physiol. 1970;10:384\u201395.","journal-title":"Respir Physiol"},{"key":"104_CR28","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/0165-1838(93)90342-R","volume":"42","author":"KG Franchini","year":"1993","unstructured":"Franchini KG, Krieger EM. Cardiovascular responses of conscious rats to carotid body chemoreceptor stimulation by intravenous KCN. J Auton Nerv Syst. 1993;42:63\u20139.","journal-title":"J Auton Nerv Syst"},{"key":"104_CR29","doi-asserted-by":"publisher","first-page":"816450","DOI":"10.1155\/2014\/816450","volume":"2014","author":"JC Queiroz","year":"2014","unstructured":"Queiroz JC, Antoniolli AR, Quintans-Junior LJ, Brito RG, Barreto RS, Costa EV, et al. Evaluation of the anti-inflammatory and antinociceptive effects of the essential oil from leaves of Xylopia laevigata in experimental models. Sci World J. 2014;2014:816450.","journal-title":"Sci World J"},{"key":"104_CR30","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/0165-0270(85)90026-3","volume":"13","author":"G Paxinos","year":"1985","unstructured":"Paxinos G, Watson C, Pennisi M, Topple A. Bregma, lambda and the interaural midpoint in stereotaxic surgery with rats of different sex, strain and weight. J Neurosci Methods. 1985;13:139\u201343.","journal-title":"J Neurosci Methods"},{"key":"104_CR31","doi-asserted-by":"publisher","first-page":"547","DOI":"10.3390\/ijms16010547","volume":"16","author":"SS Nascimento","year":"2014","unstructured":"Nascimento SS, Araujo AA, Brito RG, Serafini MR, Menezes PP, DeSantana JM, et al. Cyclodextrin-complexed Ocimum basilicum leaves essential oil increases Fos protein expression in the central nervous system and produce an antihyperalgesic effect in animal models for fibromyalgia. Int J Mol Sci. 2014;16:547\u201363.","journal-title":"Int J Mol Sci"},{"key":"104_CR32","doi-asserted-by":"publisher","first-page":"e1005458","DOI":"10.1371\/journal.pgen.1005458","volume":"11","author":"J Davila","year":"2015","unstructured":"Davila J, Laws MJ, Kannan A, Li Q, Taylor RN, Bagchi MK, et al. Rac1 regulates endometrial secretory function to control placental development. PLoS Genet. 2015;11:e1005458.","journal-title":"PLoS Genet"},{"key":"104_CR33","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1161\/01.CIR.84.2.482","volume":"84","author":"A Malliani","year":"1991","unstructured":"Malliani A, Pagani M, Lombardi F, Cerutti S. Cardiovascular neural regulation explored in the frequency domain. Circulation. 1991;84:482\u201392.","journal-title":"Circulation"},{"key":"104_CR34","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/S1566-0702(01)00267-3","volume":"90","author":"L Bernardi","year":"2001","unstructured":"Bernardi L, Porta C, Gabutti A, Spicuzza L, Sleight P. Modulatory effects of respiration. Auton Neurosci. 2001;90:47\u201356.","journal-title":"Auton Neurosci"},{"key":"104_CR35","doi-asserted-by":"publisher","first-page":"972","DOI":"10.1113\/expphysiol.2009.048306","volume":"94","author":"DB Zoccal","year":"2009","unstructured":"Zoccal DB, Bonagamba LG, Paton JF, Machado BH. Sympathetic-mediated hypertension of awake juvenile rats submitted to chronic intermittent hypoxia is not linked to baroreflex dysfunction. Exp Physiol. 2009;94:972\u201383.","journal-title":"Exp Physiol"},{"key":"104_CR36","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.exger.2012.11.009","volume":"48","author":"GC Tezini","year":"2013","unstructured":"Tezini GC, Dias DP, Souza HC. Aerobic physical training has little effect on cardiovascular autonomic control in aging rats subjected to early menopause. Exp Gerontol. 2013;48:147\u201353.","journal-title":"Exp Gerontol"},{"key":"104_CR37","doi-asserted-by":"publisher","DOI":"10.1186\/s40659-016-0073-8","volume":"49","author":"R Iturriaga","year":"2016","unstructured":"Iturriaga R, Del Rio R, Idiaquez J, Somers VK. Carotid body chemoreceptors, sympathetic neural activation, and cardiometabolic disease. Biol Res. 2016;49:13.","journal-title":"Biol Res"},{"key":"104_CR38","doi-asserted-by":"publisher","first-page":"2245","DOI":"10.1113\/jphysiol.2012.247759","volume":"591","author":"NR Prabhakar","year":"2013","unstructured":"Prabhakar NR. Sensing hypoxia: physiology, genetics and epigenetics. J Physiol. 2013;591:2245\u201357.","journal-title":"J Physiol"},{"key":"104_CR39","doi-asserted-by":"publisher","first-page":"907","DOI":"10.3945\/jn.114.202804","volume":"145","author":"JL Brito Alves de","year":"2015","unstructured":"de Brito Alves JL, Nogueira VO, Cavalcanti Neto MP, Leopoldino AM, Curti C, Colombari DS, et al. Maternal protein restriction increases respiratory and sympathetic activities and sensitizes peripheral chemoreflex in male rat offspring. J Nutr. 2015;145:907\u201314.","journal-title":"J Nutr"},{"key":"104_CR40","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1113\/EP085624","volume":"101","author":"NR Prabhakar","year":"2016","unstructured":"Prabhakar NR. Carotid body chemoreflex: a driver of autonomic abnormalities in sleep apnoea. Exp Physiol. 2016;101:975\u201385.","journal-title":"Exp Physiol"},{"key":"104_CR41","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1007\/s11906-013-0366-z","volume":"15","author":"JF Paton","year":"2013","unstructured":"Paton JF, Ratcliffe L, Hering D, Wolf J, Sobotka PA, Narkiewicz K. Revelations about carotid body function through its pathological role in resistant hypertension. Curr Hypertens Rep. 2013;15:273\u201380.","journal-title":"Curr Hypertens Rep"},{"key":"104_CR42","doi-asserted-by":"publisher","first-page":"2484","DOI":"10.1152\/jappl.1988.65.6.2484","volume":"65","author":"S Barnett","year":"1988","unstructured":"Barnett S, Mulligan E, Wagerle LC, Lahiri S. Measurement of carotid body blood flow in cats by use of radioactive microspheres. J Appl Physiol (1985). 1988;65:2484\u20139. Epub1988\/12\/01","journal-title":"J Appl Physiol (1985)"},{"issue":"10","key":"104_CR43","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1038\/nm.4173","volume":"22","author":"Wioletta Pijacka","year":"2016","unstructured":"Pijacka W, Moraes DJ, Ratcliffe LE, Nightingale AK, Hart EC, da Silva MP, et al. Purinergic receptors in the carotid body as a new drug target for controlling hypertension. Nat Med. 2016;22:1151\u20139.","journal-title":"Nature Medicine"},{"key":"104_CR44","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1038\/hr.2016.21","volume":"39","author":"P Svitok","year":"2016","unstructured":"Svitok P, Molcan L, Stebelova K, Vesela A, Sedlackova N, Ujhazy E, et al. Prenatal hypoxia in rats increased blood pressure and sympathetic drive of the adult offspring. Hypertens Res. 2016;39:501\u20135.","journal-title":"Hypertens Res"},{"key":"104_CR45","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1161\/CIRCRESAHA.109.206946","volume":"106","author":"ZY Tan","year":"2010","unstructured":"Tan ZY, Lu Y, Whiteis CA, Simms AE, Paton JF, Chapleau MW, et al. Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR. Circ Res. 2010;106:536\u201345.","journal-title":"Circ Res"},{"key":"104_CR46","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1161\/HYPERTENSIONAHA.111.00064","volume":"61","author":"JF Paton","year":"2013","unstructured":"Paton JF, Sobotka PA, Fudim M, Engelman ZJ, Hart EC, McBryde FD, et al. The carotid body as a therapeutic target for the treatment of sympathetically mediated diseases. Hypertension. 2013;61:5\u201313.","journal-title":"Hypertension"},{"key":"104_CR47","doi-asserted-by":"publisher","first-page":"4269","DOI":"10.1113\/jphysiol.2012.237800","volume":"590","author":"AP Abdala","year":"2012","unstructured":"Abdala AP, McBryde FD, Marina N, Hendy EB, Engelman ZJ, Fudim M, et al. Hypertension is critically dependent on the carotid body input in the spontaneously hypertensive rat. J Physiol. 2012;590:4269\u201377.","journal-title":"J Physiol"},{"key":"104_CR48","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1038\/hr.2011.209","volume":"35","author":"M Sinski","year":"2012","unstructured":"Sinski M, Lewandowski J, Przybylski J, Bidiuk J, Abramczyk P, Ciarka A, et al. Tonic activity of carotid body chemoreceptors contributes to the increased sympathetic drive in essential hypertension. Hypertens Res. 2012;35:487\u201391.","journal-title":"Hypertens Res"},{"issue":"3","key":"104_CR49","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1002\/ejhf.641","volume":"19","author":"Piotr Niewinski","year":"2016","unstructured":"Niewinski P, Janczak D, Rucinski A, Tubek S, Engelman ZJ, Piesiak P, et al. Carotid body resection for sympathetic modulation in systolic heart failure: results from first-in-man study. Eur J Heart Fail. 2017;19:391\u2013400.","journal-title":"European Journal of Heart Failure"},{"key":"104_CR50","doi-asserted-by":"publisher","first-page":"11315","DOI":"10.1523\/JNEUROSCI.23-36-11315.2003","volume":"23","author":"W Rong","year":"2003","unstructured":"Rong W, Gourine AV, Cockayne DA, Xiang Z, Ford AP, Spyer KM, et al. Pivotal role of nucleotide P2X2 receptor subunit of the ATP-gated ion channel mediating ventilatory responses to hypoxia. J Neurosci. 2003;23:11315\u201321.","journal-title":"J Neurosci"},{"key":"104_CR51","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.bbrc.2004.07.081","volume":"322","author":"J Buttigieg","year":"2004","unstructured":"Buttigieg J, Nurse CA. Detection of hypoxia-evoked ATP release from chemoreceptor cells of the rat carotid body. Biochem Biophys Res Commun. 2004;322:82\u20137.","journal-title":"Biochem Biophys Res Commun"},{"key":"104_CR52","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1111\/j.1471-4159.2004.02380.x","volume":"89","author":"SV Conde","year":"2004","unstructured":"Conde SV, Monteiro EC. Hypoxia induces adenosine release from the rat carotid body. J Neurochem. 2004;89:1148\u201356.","journal-title":"J Neurochem"},{"key":"104_CR53","doi-asserted-by":"publisher","first-page":"2002","DOI":"10.1152\/japplphysiol.01617.2011","volume":"112","author":"SV Conde","year":"2012","unstructured":"Conde SV, Monteiro EC, Rigual R, Obeso A, Gonzalez C. Hypoxic intensity: a determinant for the contribution of ATP and adenosine to the genesis of carotid body chemosensory activity. J Appl Physiol (1985). 2012;112:2002\u201310.","journal-title":"J Appl Physiol (1985)"},{"key":"104_CR54","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/0306-4522(87)90214-4","volume":"22","author":"GD Housley","year":"1987","unstructured":"Housley GD, Martin-Body RL, Dawson NJ, Sinclair JD. Brain stem projections of the glossopharyngeal nerve and its carotid sinus branch in the rat. Neuroscience. 1987;22:237\u201350.","journal-title":"Neuroscience"},{"key":"104_CR55","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/0301-0082(94)90064-7","volume":"42","author":"RA Dampney","year":"1994","unstructured":"Dampney RA. The subretrofacial vasomotor nucleus: anatomical, chemical and pharmacological properties and role in cardiovascular regulation. Prog Neurobiol. 1994;42:197\u2013227.","journal-title":"Prog Neurobiol"},{"key":"104_CR56","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/0301-0082(95)00026-8","volume":"47","author":"MK Sun","year":"1995","unstructured":"Sun MK. Central neural organization and control of sympathetic nervous system in mammals. Prog Neurobiol. 1995;47:157\u2013233.","journal-title":"Prog Neurobiol"},{"key":"104_CR57","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1007\/978-0-387-73693-8_57","volume":"605","author":"PG Guyenet","year":"2008","unstructured":"Guyenet PG, Bayliss DA, Mulkey DK, Stornetta RL, Moreira TS, Takakura AT. The retrotrapezoid nucleus and central chemoreception. Adv Exp Med Biol. 2008;605:327\u201332.","journal-title":"Adv Exp Med Biol"},{"key":"104_CR58","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1113\/EP085615","volume":"101","author":"AC Takakura","year":"2016","unstructured":"Takakura AC, Moreira TS. The retrotrapezoid nucleus as a central brainstem area for central and peripheral chemoreceptor interactions. Exp Physiol. 2016;101:455\u20136.","journal-title":"Exp Physiol"},{"key":"104_CR59","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1164\/rccm.201106-0971PP","volume":"184","author":"JL Todd","year":"2011","unstructured":"Todd JL, Goldstein DB, Ge D, Christie J, Palmer SM. The state of genome-wide association studies in pulmonary disease: a new perspective. Am J Respir Crit Care Med. 2011;184:873\u201380.","journal-title":"Am J Respir Crit Care Med"},{"key":"104_CR60","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1002\/path.4470","volume":"235","author":"E Zana-Taieb","year":"2015","unstructured":"Zana-Taieb E, Pham H, Franco-Montoya ML, Jacques S, Letourneur F, Baud O, et al. Impaired alveolarization and intra-uterine growth restriction in rats: a postnatal genome-wide analysis. J Pathol. 2015;235:420\u201330.","journal-title":"J Pathol"},{"key":"104_CR61","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.lfs.2017.04.020","volume":"179","author":"YX Ding","year":"2017","unstructured":"Ding YX, Cui H. Integrated analysis of genome-wide DNA methylation and gene expression data provide a regulatory network in intrauterine growth restriction. Life Sci. 2017;179:60\u20135.","journal-title":"Life Sci"},{"key":"104_CR62","doi-asserted-by":"publisher","first-page":"15111","DOI":"10.1074\/jbc.M109.095133","volume":"285","author":"RF Thompson","year":"2010","unstructured":"Thompson RF, Fazzari MJ, Niu H, Barzilai N, Simmons RA, Greally JM. Experimental intrauterine growth restriction induces alterations in DNA methylation and gene expression in pancreatic islets of rats. J Biol Chem. 2010;285:15111\u20138.","journal-title":"J Biol Chem"},{"key":"104_CR63","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1073\/pnas.0808358106","volume":"106","author":"Y Wang","year":"2009","unstructured":"Wang Y, O\u2019Connell JR, McArdle PF, Wade JB, Dorff SE, Shah SJ, et al. From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene. Proc Natl Acad Sci USA. 2009;106:226\u201331.","journal-title":"Proc Natl Acad Sci USA"},{"issue":"2","key":"104_CR64","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1002\/em.22140","volume":"59","author":"Rufeng Shi","year":"2017","unstructured":"Shi R, Li J, He J, Meng Q, Qian Z, Shi D, et al. Association of with-no-lysine kinase 1 and Serine\/Threonine kinase 39 gene polymorphisms and haplotypes with essential hypertension in Tibetans. Environ Mol Mutagen. 2018;59:151\u201360.","journal-title":"Environmental and Molecular Mutagenesis"},{"key":"104_CR65","doi-asserted-by":"publisher","first-page":"2288","DOI":"10.1093\/hmg\/ddp135","volume":"18","author":"E Org","year":"2009","unstructured":"Org E, Eyheramendy S, Juhanson P, Gieger C, Lichtner P, Klopp N, et al. Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations. Hum Mol Genet. 2009;18:2288\u201396.","journal-title":"Hum Mol Genet"},{"key":"104_CR66","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1161\/HYPERTENSIONAHA.110.150425","volume":"56","author":"EB Oliveira-Sales","year":"2010","unstructured":"Oliveira-Sales EB, Colombari DS, Davisson RL, Kasparov S, Hirata AE, Campos RR, et al. Kidney-induced hypertension depends on superoxide signaling in the rostral ventrolateral medulla. Hypertension. 2010;56:290\u20136.","journal-title":"Hypertension"},{"key":"104_CR67","doi-asserted-by":"crossref","unstructured":"Wallbach M, Koziolek MJ. Baroreceptors in the carotid and hypertension-systematic review and meta-analysis of the effects of baroreflex activation therapy on blood pressure. Nephrol Dial Transplant. 2017;33:1485\u201393.","DOI":"10.1093\/ndt\/gfx279"},{"key":"104_CR68","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.autneu.2009.12.007","volume":"155","author":"VA Braga","year":"2010","unstructured":"Braga VA. Dietary salt enhances angiotensin-II-induced superoxide formation in the rostral ventrolateral medulla. Auton Neurosci. 2010;155:14\u20138.","journal-title":"Auton Neurosci"},{"key":"104_CR69","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1111\/j.1365-2796.2007.01776.x","volume":"261","author":"S Johansson","year":"2007","unstructured":"Johansson S, Norman M, Legnevall L, Dalmaz Y, Lagercrantz H, Vanpee M. Increased catecholamines and heart rate in children with low birth weight: perinatal contributions to sympathoadrenal overactivity. J Intern Med Suppl. 2007;261:480\u20137.","journal-title":"J Intern Med Suppl"},{"key":"104_CR70","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.amsu.2013.11.002","volume":"3","author":"ER Carthy","year":"2014","unstructured":"Carthy ER. Autonomic dysfunction in essential hypertension: a systematic review. Ann Med Surg. 2014;3:2\u20137.","journal-title":"Ann Med Surg"},{"key":"104_CR71","doi-asserted-by":"publisher","first-page":"R8","DOI":"10.1152\/ajpregu.00147.2008","volume":"295","author":"R Kanbar","year":"2008","unstructured":"Kanbar R, Chapuis B, Orea V, Barres C, Julien C. Baroreflex control of lumbar and renal sympathetic nerve activity in conscious rats. Am J Physiol Regul Integr Comp Physiol. 2008;295:R8\u2013R14.","journal-title":"Am J Physiol Regul Integr Comp Physiol"}],"container-title":["Hypertension Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/s41440-018-0104-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41440-018-0104-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41440-018-0104-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T21:19:26Z","timestamp":1684617566000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41440-018-0104-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,21]]},"references-count":71,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["104"],"URL":"https:\/\/doi.org\/10.1038\/s41440-018-0104-7","relation":{},"ISSN":["0916-9636","1348-4214"],"issn-type":[{"value":"0916-9636","type":"print"},{"value":"1348-4214","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,21]]},"assertion":[{"value":"13 March 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 March 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 September 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. VN, and JB-A contributed to experiments with conscious rats. VON, JB-A, DF, LO, WLJr, YT, GSFdS, AW, CL, and JHC-S contributed to the conception and experimental design, data analyses, and interpretation of the findings and the preparation of this manuscript. All authors read and approved the final version of the manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}