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Research support: HW (AstraZeneca, Otsuka Pharmaceutical, and Kaneka Corporation) Honoraria: HW (AstraZeneca, Otsuka Pharmaceutical, Kaneka Corporation, Kyowa Kirin, Sanwa Kagaku, Chugai Pharma, Kowa, Otsuka Pharmaceutical, Novartis, Mitsubishi-Tanabe Pharma, Bayer, and Daiichi-Sankyo Pharma). Lecture fees: MT (Boehringer Ingelheim, Eli Lilly, Novo Nordisk, Sumitomo, and Mitsubishi Tanabe). Subsidies: MT (Super Light Water, TAKAGI, Roche DC, and LifeScan). Honoraria\/lecture fees: KT (AstraZeneca, Novartes, Bayer, Otsuka Pharmaceutical, Boehringer Ingelheim, Fuji Pharma, Kyowa Kirin, Ono Pharmaceutical, Sanwa Kagaku, Mochida Pharmaceutical, Kowa, Eli Lilly, Novo Nordisk). Commissioned clinical trials, contract research, and joint research funding: MT (AstraZeneca, Bayer, Novartis, Chinook, Otsuka Medical Devices, Novo Nordisk, Terumo, Variatris, and Kowa). 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