{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:50:56Z","timestamp":1792086656613,"version":"4.4.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hypertens Res"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Hypertension is strongly linked to obesity, yet it remains uncertain whether DXA-derived measures of adiposity improve hypertension discrimination beyond routine anthropometric assessment and whether any incremental value reflects visceral rather than total adiposity. This study examined whether DXA-derived visceral and total adiposity provide incremental discriminatory value beyond routine anthropometric assessment for hypertension discrimination. We analyzed 7817 adults aged 20\u201359 years from the 2013 to 2018 National Health and Nutrition Examination Survey with valid DXA measurements. Discriminatory performance and the incremental value of DXA-derived adiposity measures beyond anthropometric assessment were evaluated using receiver operating characteristic curve analysis, model fit, and reclassification metrics. Among routinely available anthropometric measures, waist circumference demonstrated the highest discriminatory performance for hypertension (AUC 0.791, 95% CI: 0.780\u20130.802). Addition of DXA-derived visceral adiposity significantly improved discrimination (AUC 0.865, \u0394AUC\u2009=\u20090.074) and significantly improved model fit beyond waist circumference (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.001), whereas total adiposity measured by fat mass index provided negligible incremental value (\u0394AUC\u2009=\u20090.0020) and did not improve model fit. Reclassification metrics yielded consistent findings, and results generally remained robust across sensitivity analyses; however, when hypertension was defined using measured blood pressure alone, the incremental improvement was attenuated (\u0394AUC\u2009=\u20090.012 vs. 0.074). Among DXA-derived adiposity measures, only visceral adiposity provided meaningful incremental discriminatory value beyond the best-performing routine anthropometric measure, whereas total adiposity did not. These findings suggest that when DXA-based body composition assessment is performed, the clinically relevant information may be derived from visceral rather than total adiposity.\n                  <\/jats:p>","DOI":"10.1038\/s41440-026-02857-5","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:33:50Z","timestamp":1792085630000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Incremental value of DXA-derived visceral versus total adiposity beyond routine anthropometric assessment for hypertension discrimination: a population-based study"],"prefix":"10.1038","author":[{"given":"Tadesse Asmamaw","family":"Dejenie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haider","family":"Mannan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan","family":"Atlantis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"key":"2857_CR1","unstructured":"Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet. 2021;398:957\u201380."},{"key":"2857_CR2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2025.1619445","volume":"12","author":"C Niu","year":"2025","unstructured":"Niu C, Zhang P, Wei L, Dong J, Xu C, Yang Q, et al. The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050. Front Cardiovasc Med. 2025;12:1619445.","journal-title":"Front Cardiovasc Med"},{"key":"2857_CR3","doi-asserted-by":"publisher","first-page":"4","DOI":"10.4082\/kjfm.25.0275","volume":"47","author":"S Cho","year":"2026","unstructured":"Cho S, Kwon H. Current guidelines and future directions in comprehensive obesity assessment. Korean J Fam Med. 2026;47:4\u201311.","journal-title":"Korean J Fam Med"},{"key":"2857_CR4","doi-asserted-by":"crossref","unstructured":"Zou Y, Ye H, Xu Z, Yang Q, Zhu J, Li T, et al. Obesity, sarcopenia, sarcopenic obesity, and hypertension: mediating role of inflammation and insulin resistance. 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Beyond BMI: rethinking obesity metrics and cardiovascular risk in the era of precision medicine. Diagnostics. 2025;15:3025.","DOI":"10.3390\/diagnostics15233025"},{"key":"2857_CR8","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1016\/j.diabres.2018.08.005","volume":"143","author":"Z Ping","year":"2018","unstructured":"Ping Z, Pei X, Xia P, Chen Y, Guo R, Hu C, et al. Anthropometric indices as surrogates for estimating abdominal visceral and subcutaneous adipose tissue: A meta-analysis with 16,129 participants. Diab Res Clin Pr. 2018;143:310\u20139.","journal-title":"Diab Res Clin Pr"},{"key":"2857_CR9","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1038\/s41574-019-0310-7","volume":"16","author":"R Ross","year":"2020","unstructured":"Ross R, Neeland IJ, Yamashita S, Shai I, Seidell J, Magni P, et al. Waist circumference as a vital sign in clinical practice: a consensus statement from the IAS and ICCR Working Group on Visceral Obesity. 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The authors declare that they have no other competing financial or personal interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}}]}}