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Phenols\/anilines being naturally abundant and the carbonyl being the most common in a wide range of bioactive molecules, an efficient conversion is of prime interest. The reported methods require transition metal catalyzed cross coupling which limits its applicability. Here we have described a method for synthesizing various aldehydes and ketones, starting from phenol and protected anilines via Csp\n                    <jats:sup>2<\/jats:sup>\n                    -O\/N bond cleavage in a one-pot\/stepwise manner. Our synthetic method is found to be compatible with a diverse range of phenols and anilines carrying sensitive functional groups including halides, esters, ketal, hydroxyl, alkenes, and terminal alkynes as well as the substitution on the aryl cores. A short-step synthesis of bioactive molecules and their functionalization have been executed. Starting from BINOL, a photocatalyst has been designed. Here, we have developed a transition metal-free protocol for the conversion of phenols and anilines to aldehydes and ketones.\n                  <\/jats:p>","DOI":"10.1038\/s41467-024-47156-0","type":"journal-article","created":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T05:02:00Z","timestamp":1715058120000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["One pot conversion of phenols and anilines to aldehydes and ketones exploiting \u03b1 gem boryl carbanions"],"prefix":"10.1038","volume":"15","author":[{"given":"Kanak Kanti","family":"Das","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debasis","family":"Aich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sutapa","family":"Dey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4720-1224","authenticated-orcid":false,"given":"Santanu","family":"Panda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,7]]},"reference":[{"key":"47156_CR1","doi-asserted-by":"publisher","first-page":"2217","DOI":"10.2174\/1385272825666210610154414","volume":"25","author":"A Leslie","year":"2021","unstructured":"Leslie, A., Joseph, A. 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