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Balasubramanian declare their competing interests as either current or former employees or consultants of Bugworks Research India Pvt. Ltd. Further, authors Shahul Hameed P., Nagakumar Bharatham, Nainesh Katagihallimath, Sreevalli Sharma, & Radha Nandishaiah are inventors on the patent WO2017199265A1, which covers compounds 1 \u2013 4 disclosed in the manuscript; and authors Shahul Hameed P., Nagakumar Bharatham, Nainesh Katagihallimath, Sreevalli Sharma, Radha Nandishaiah, Vasanthi Ramachandran and V. Balasubramanian are inventors on the patent WO2018225097A1, which covers compounds 5\u2013 9 disclosed in the manuscript. The authors Claire Sadler, Ian Slater, Michael Morton, Amy Watters, Holly Becker, Jill Lindley, Robert Flamm, Michael Huband, Dan Sahm, Meredith Hackel, Tarun Mathur, Ruwanthi Kolamunnage-Dona, Jennifer Unsworth, Laura Mcentee, Nikki Farrington, Dhanasekaran Manickam, Chandrashekara Narayana, Sivakandan Jayachandiran, Hrushikesava Reddy, Sathya Shanker, Ramesh Jayaraman, Mahesh Nanjundappa, Vijay Richard, Teby Thomas, Savitha Nagaraj, and Shampa Das declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"8202"}}