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B.B. reports personal consultancy fees as Advisory board member from Standard BioTools. B.S. was a scientific co-founder of Allcyte, which has been acquired by Exscientia. B.S. is a shareholder of Exscientia and a co-inventor on US patent application 15\/514,045 relevant to the study. L.P. and G.G. are listed as inventors on patents related to the 4i technology (WO 2019\/207004; WO 2020\/008071). G.R. is listed on a patent application related to single-cell analyses (European Patent Application No. 20170724.7), and G.R. is cofounder and on the Scientific Advisory Board of Computomics GmbH. H.M. is on advisory boards for Bayer, Astra Zeneca, Janssen, Roche, and Merck. M.P.L. is scientific advisor and board member of Oncobit and has received unrelated research funding from Roche, Novartis, Scailyte, Molecular Partners, and Bacoba. V.H.K. is an invited speaker for Sharing Progress in Cancer Care (SPCC) and Indica Labs; advisory board of Takeda; sponsored research agreements with Roche and IAG all unrelated to the current study; listed as innovator on patent applications in computational pathology. The Tumor Profiler study is jointly funded by a public-private partnership involving F. Hoffmann-La Roche Ltd., ETH Zurich, University of Zurich, University Hospital Zurich, and University Hospital Basel. The remaining authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"9402"}}