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For example, courtship behavior involves sensorimotor processing of signals that can result in behavioral dialog between partners, such as stereotyped movements and singing. The courtship behavior of\n                    <jats:italic>Drosophila melanogaster<\/jats:italic>\n                    males with their partners, which are usually female but can also be male, involves singing. To investigate how behavioral feedback and sensorimotor processing contribute to flexible social interactions, we compared the courtship behavior and singing of male\n                    <jats:italic>D. melanogaster<\/jats:italic>\n                    towards males and females. Quantitative analysis of their interactions revealed that while underlying courtship and song rules are unaffected by the sex of the partner, the behavioral dynamics and song sequences differ by partner sex. This divergence stems from sex-specific behavioral feedback: females decelerate to song, while males orient towards the singer. Moreover, optogenetic manipulations reveal that the partners\u2019 responses are driven by sex-specific neural circuits that link song detection with arousal and social decisions. Our findings demonstrate that flexible social behaviors can arise from fixed sensorimotor rules through a context-dependent selection facilitated by the partner\u2019s behavioral feedback. More broadly, our results reveal compositionality as a key mechanism for achieving behavioral flexibility during complex social interactions such as courtship.\n                  <\/jats:p>","DOI":"10.1038\/s41467-026-72057-9","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T12:36:00Z","timestamp":1777898160000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sex-specific behavioral feedback modulates sensorimotor processing and drives flexible social behavior"],"prefix":"10.1038","volume":"17","author":[{"given":"Sarath","family":"Ravindran Nair","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9335-7767","authenticated-orcid":false,"given":"Adri\u00e1n","family":"Palacios-Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sage","family":"Martineau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malak","family":"Nasr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4200-8097","authenticated-orcid":false,"given":"Jan","family":"Clemens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"72057_CR1","doi-asserted-by":"crossref","unstructured":"Brown, V. 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