{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T09:40:27Z","timestamp":1792662027517,"version":"4.5.0"},"reference-count":61,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001691","name":"MEXT | Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20K21424"],"award-info":[{"award-number":["20K21424"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"MEXT | Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20H02473"],"award-info":[{"award-number":["20H02473"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"MEXT | Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["26KJ1307"],"award-info":[{"award-number":["26KJ1307"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"MEXT | Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["22H00360"],"award-info":[{"award-number":["22H00360"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002241","name":"MEXT | Japan Science and Technology Agency","doi-asserted-by":"publisher","award":["JPMJER2403"],"award-info":[{"award-number":["JPMJER2403"]}],"id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008887","name":"Suntory Foundation","doi-asserted-by":"publisher","award":["SUMBOR"],"award-info":[{"award-number":["SUMBOR"]}],"id":[{"id":"10.13039\/501100008887","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat. Plants"],"DOI":"10.1038\/s41477-026-02438-x","type":"journal-article","created":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T09:01:38Z","timestamp":1792659698000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Synthetic activation of gibberellin signalling reveals spatial coordination of root growth"],"prefix":"10.1038","author":[{"given":"Yuichiro","family":"Yagami","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryotaro","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuuma","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiki","family":"Meguro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhei","family":"Kusano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5227-7894","authenticated-orcid":false,"given":"Kenichiro","family":"Itami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6465-0115","authenticated-orcid":false,"given":"Wolf B.","family":"Frommer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Hagihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7107-4942","authenticated-orcid":false,"given":"Masayoshi","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,22]]},"reference":[{"key":"2438_CR1","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1146\/annurev.arplant.59.032607.092804","volume":"59","author":"S Yamaguchi","year":"2008","unstructured":"Yamaguchi, S. Gibberellin metabolism and its regulation. Ann. Rev. Plant Biol. 59, 225\u2013251 (2008).","journal-title":"Ann. Rev. Plant Biol."},{"key":"2438_CR2","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1093\/jxb\/ern301","volume":"60","author":"P Achard","year":"2009","unstructured":"Achard, P. & Genschik, P. Releasing the brakes of plant growth: how GAs shutdown DELLA proteins. J. Exp. Bot. 60, 1085\u20131092 (2009).","journal-title":"J. Exp. Bot."},{"key":"2438_CR3","doi-asserted-by":"publisher","first-page":"3194","DOI":"10.1101\/gad.11.23.3194","volume":"11","author":"J Peng","year":"1997","unstructured":"Peng, J. et al. The Arabidopsis GAI gene defines a signaling pathway that negatively regulates gibberellin responses. Genes Dev. 11, 3194\u20133205 (1997).","journal-title":"Genes Dev."},{"key":"2438_CR4","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1038\/416701a","volume":"416","author":"A Sasaki","year":"2002","unstructured":"Sasaki, A. et al. A mutant gibberellin-synthesis gene in rice. Nature 416, 701\u2013702 (2002).","journal-title":"Nature"},{"key":"2438_CR5","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1038\/nbt847","volume":"21","author":"T Sakamoto","year":"2003","unstructured":"Sakamoto, T. et al. Genetic manipulation of gibberellin metabolism in transgenic rice. Nat. Biotechnol. 21, 909\u2013913 (2003).","journal-title":"Nat. Biotechnol."},{"key":"2438_CR6","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1038\/nature04028","volume":"437","author":"M Ueguchi-Tanaka","year":"2005","unstructured":"Ueguchi-Tanaka, M. et al. GIBBERELLIN INSENSITIVE DWARF1 encodes a soluble receptor for gibberellin. Nature 437, 693\u2013698 (2005).","journal-title":"Nature"},{"key":"2438_CR7","doi-asserted-by":"publisher","first-page":"2140","DOI":"10.1105\/tpc.106.043729","volume":"19","author":"M Ueguchi-Tanaka","year":"2007","unstructured":"Ueguchi-Tanaka, M. et al. Molecular interactions of a soluble gibberellin receptor, GID1, with a rice DELLA protein, SLR1, and gibberellin. Plant Cell 19, 2140\u20132155 (2007).","journal-title":"Plant Cell"},{"key":"2438_CR8","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1105\/tpc.107.051441","volume":"19","author":"BC Willige","year":"2007","unstructured":"Willige, B. C. et al. The DELLA domain of GA INSENSITIVE mediates the interaction with the GA INSENSITIVE DWARF1A gibberellin receptor of Arabidopsis. Plant Cell 19, 1209\u20131220 (2007).","journal-title":"Plant Cell"},{"key":"2438_CR9","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1038\/nature07519","volume":"456","author":"K Murase","year":"2008","unstructured":"Murase, K., Hirano, Y., Sun, T. & Hakoshima, T. Gibberellin-induced DELLA recognition by the gibberellin receptor GID1. Nature 456, 459\u2013463 (2008).","journal-title":"Nature"},{"key":"2438_CR10","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1038\/nature07546","volume":"456","author":"A Shimada","year":"2008","unstructured":"Shimada, A. et al. Structural basis for gibberellin recognition by its receptor GID1. Nature 456, 520\u2013523 (2008).","journal-title":"Nature"},{"key":"2438_CR11","doi-asserted-by":"publisher","first-page":"3399","DOI":"10.1105\/tpc.106.047415","volume":"18","author":"J Griffiths","year":"2006","unstructured":"Griffiths, J. et al. Genetic characterization and functional analysis of the GID1 gibberellin receptors in Arabidopsis. Plant Cell 18, 3399\u20133414 (2006).","journal-title":"Plant Cell"},{"key":"2438_CR12","doi-asserted-by":"publisher","first-page":"1521","DOI":"10.1111\/nph.16967","volume":"229","author":"R Barker","year":"2021","unstructured":"Barker, R. et al. Mapping sites of gibberellin biosynthesis in the Arabidopsis root tip. New Phytol. 229, 1521\u20131534 (2021).","journal-title":"New Phytol."},{"key":"2438_CR13","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1093\/genetics\/159.2.777","volume":"159","author":"A Dill","year":"2001","unstructured":"Dill, A. & Sun, T. Synergistic derepression of gibberellin signaling by removing RGA and GAI function in Arabidopsis thaliana. Genetics 159, 777\u2013785 (2001).","journal-title":"Genetics"},{"key":"2438_CR14","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1016\/j.cub.2009.06.023","volume":"19","author":"S Ubeda-Tom\u00e1s","year":"2009","unstructured":"Ubeda-Tom\u00e1s, S. et al. Gibberellin signaling in the endodermis controls Arabidopsis root meristem size. Curr. Biol. 19, 1194\u20131199 (2009).","journal-title":"Curr. Biol."},{"key":"2438_CR15","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1038\/ncb1726","volume":"10","author":"S Ubeda-Tom\u00e1s","year":"2008","unstructured":"Ubeda-Tom\u00e1s, S. et al. Root growth in Arabidopsis requires gibberellin\/DELLA signalling in the endodermis. Nat. Cell Biol. 10, 625\u2013628 (2008).","journal-title":"Nat. Cell Biol."},{"key":"2438_CR16","doi-asserted-by":"publisher","first-page":"4834","DOI":"10.1073\/pnas.1300436110","volume":"110","author":"E Shani","year":"2013","unstructured":"Shani, E. et al. Gibberellins accumulate in the elongating endodermal cells of Arabidopsis root. Proc. Natl Acad. Sci. USA 110, 4834\u20134839 (2013).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"2438_CR17","doi-asserted-by":"publisher","first-page":"4698","DOI":"10.1073\/pnas.96.8.4698","volume":"96","author":"SG Thomas","year":"1999","unstructured":"Thomas, S. G., Phillips, A. L. & Hedden, P. Molecular cloning and functional expression of gibberellin 2- oxidases, multifunctional enzymes involved in gibberellin deactivation. Proc. Natl Acad. Sci. USA 96, 4698\u20134703 (1999).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"2438_CR18","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1016\/S1360-1385(00)01790-8","volume":"5","author":"P Hedden","year":"2000","unstructured":"Hedden, P. & Phillips, A. L. Gibberellin metabolism: new insights revealed by the genes. Trends Plant Sci. 5, 523\u2013530 (2000).","journal-title":"Trends Plant Sci."},{"key":"2438_CR19","doi-asserted-by":"publisher","first-page":"4613","DOI":"10.1007\/s00894-013-1971-0","volume":"19","author":"H Duan","year":"2013","unstructured":"Duan, H., Li, D., Liu, H., Liang, D. & Yang, X. Computational insight into novel molecular recognition mechanism of different bioactive GAs and the Arabidopsis receptor GID1A. J. Mol. Model. 19, 4613\u20134624 (2013).","journal-title":"J. Mol. Model."},{"key":"2438_CR20","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1038\/s41477-017-0021-9","volume":"3","author":"A Rizza","year":"2017","unstructured":"Rizza, A., Walia, A., Lanquar, V., Frommer, W. B. & Jones, A. M. In vivo gibberellin gradients visualized in rapidly elongating tissues. Nat. Plants 3, 803\u2013813 (2017).","journal-title":"Nat. Plants"},{"key":"2438_CR21","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13245","volume":"7","author":"Y Kanno","year":"2016","unstructured":"Kanno, Y. et al. AtSWEET13 and AtSWEET14 regulate gibberellin-mediated physiological processes. Nat. Commun. 7, 13245 (2016).","journal-title":"Nat. Commun."},{"key":"2438_CR22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2207558119","volume":"119","author":"R Isoda","year":"2022","unstructured":"Isoda, R. et al. SWEET13 transport of sucrose, but not gibberellin, restores male fertility in Arabidopsis sweet13;14. Proc. Natl Acad. Sci. USA 119, e2207558119 (2022).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"2438_CR23","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1111\/j.1365-313X.2005.02642.x","volume":"45","author":"MG Mitchum","year":"2006","unstructured":"Mitchum, M. G. et al. Distinct and overlapping roles of two gibberellin 3-oxidases in Arabidopsis development. Plant J. 45, 804\u2013818 (2006).","journal-title":"Plant J."},{"key":"2438_CR24","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1016\/S0092-8674(00)80115-4","volume":"86","author":"LD Laurenzio","year":"1996","unstructured":"Laurenzio, L. D. et al. The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root. Cell 86, 423\u2013433 (1996).","journal-title":"Cell"},{"key":"2438_CR25","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1046\/j.1365-313X.1997.12040957.x","volume":"12","author":"JE Malamy","year":"1997","unstructured":"Malamy, J. E. & Benfey, P. N. Analysis of SCARECROW expression using a rapid system for assessing transgene expression in Arabidopsis roots. Plant J. 12, 957\u2013963 (1997).","journal-title":"Plant J."},{"key":"2438_CR26","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1126\/science.1153795","volume":"320","author":"JR Dinneny","year":"2008","unstructured":"Dinneny, J. R. et al. Cell identity mediates the response of Arabidopsis roots to abiotic stress. Science 320, 942\u2013945 (2008).","journal-title":"Science"},{"key":"2438_CR27","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1016\/S0092-8674(00)81536-6","volume":"99","author":"MM Lee","year":"1999","unstructured":"Lee, M. M. & Schiefelbein, J. WEREWOLF, a MYB-related protein in Arabidopsis, is a position-dependent regulator of epidermal cell patterning. Cell 99, 473\u2013483 (1999).","journal-title":"Cell"},{"key":"2438_CR28","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/S0070-2153(10)91007-7","volume":"91","author":"H Breuninger","year":"2010","unstructured":"Breuninger, H. & Lenhard, M. Control of tissue and organ growth in plants. Curr. Top. Dev. Biol. 91, 185\u2013220 (2010).","journal-title":"Curr. Top. Dev. Biol."},{"key":"2438_CR29","doi-asserted-by":"publisher","first-page":"1954","DOI":"10.4161\/psb.6.12.18079","volume":"6","author":"S Miyashima","year":"2011","unstructured":"Miyashima, S. & Nakajima, K. The root endodermis: a hub of developmental signals and nutrient flow. Plant Signal. Behav. 6, 1954\u20131958 (2011).","journal-title":"Plant Signal. Behav."},{"key":"2438_CR30","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1038\/nature05618","volume":"446","author":"S Savaldi-Goldstein","year":"2007","unstructured":"Savaldi-Goldstein, S., Peto, C. & Chory, J. The epidermis both drives and restricts plant shoot growth. Nature 446, 199\u2013202 (2007).","journal-title":"Nature"},{"key":"2438_CR31","doi-asserted-by":"publisher","first-page":"1964","DOI":"10.1101\/gad.305504","volume":"18","author":"R Heidstra","year":"2004","unstructured":"Heidstra, R., Welch, D. & Scheres, B. Mosaic analysis using marked activation and deletion clones dissect Arabidopsis SCARCROW action in asymmetric cell division. Genes Dev. 18, 1964\u20131969 (2004).","journal-title":"Genes Dev."},{"key":"2438_CR32","first-page":"18","volume":"1","author":"J Binenbaum","year":"2023","unstructured":"Binenbaum, J. et al. Gibberellin and abscisic acid transporters facilitate endodermal suberin formation in Arabidopsis. Nat. Plants 1, 18 (2023).","journal-title":"Nat. Plants"},{"key":"2438_CR33","first-page":"840","volume":"48","author":"T Denyer","year":"2018","unstructured":"Denyer, T. et al. Spatiotemporal developmental trajectories in the Arabidopsis root revealed using high-throughput single cell RNA sequencing. SSRN Electron. J. 48, 840\u2013852 (2018).","journal-title":"SSRN Electron. J."},{"key":"2438_CR34","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1016\/j.molp.2019.04.004","volume":"12","author":"T-Q Zhang","year":"2019","unstructured":"Zhang, T.-Q., Xu, Z.-G., Shang, G.-D. & Wang, J.-W. A single-cell RNA sequencing profiles the developmental landscape of Arabidopsis root. Mol. Plant 12, 648\u2013660 (2019).","journal-title":"Mol. Plant"},{"key":"2438_CR35","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1105\/tpc.18.00785","volume":"31","author":"K Jean-Baptiste","year":"2019","unstructured":"Jean-Baptiste, K. et al. Dynamics of gene expression in single root cells of Arabidopsis thaliana. Plant Cell 31, 993\u20131011 (2019).","journal-title":"Plant Cell"},{"key":"2438_CR36","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/j.devcel.2022.01.008","volume":"57","author":"R Shahan","year":"2022","unstructured":"Shahan, R. et al. A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants. Dev. Cell 57, 543\u2013560 (2022).","journal-title":"Dev. Cell"},{"key":"2438_CR37","doi-asserted-by":"publisher","DOI":"10.1126\/science.aay4970","volume":"370","author":"JR Wendrich","year":"2020","unstructured":"Wendrich, J. R. et al. Vascular transcription factors guide plant epidermal responses to limiting phosphate conditions. Science 370, eaay4970 (2020).","journal-title":"Science"},{"key":"2438_CR38","doi-asserted-by":"publisher","first-page":"1444","DOI":"10.1104\/pp.18.01482","volume":"179","author":"KH Ryu","year":"2019","unstructured":"Ryu, K. H., Huang, L., Kang, H. M. & Schiefelbein, J. Single-cell RNA sequencing resolves molecular relationships among individual plant cells. Plant Physiol. 179, 1444\u20131456 (2019).","journal-title":"Plant Physiol."},{"key":"2438_CR39","doi-asserted-by":"publisher","first-page":"2241","DOI":"10.1016\/j.celrep.2019.04.054","volume":"27","author":"CN Shulse","year":"2019","unstructured":"Shulse, C. N. et al. High-throughput single-cell transcriptome profiling of plant cell types. Cell Rep. 27, 2241\u20132247 (2019).","journal-title":"Cell Rep."},{"key":"2438_CR40","doi-asserted-by":"publisher","DOI":"10.1038\/nplants.2015.73","volume":"1","author":"T Regnault","year":"2015","unstructured":"Regnault, T. et al. The gibberellin precursor GA12 acts as a long-distance growth signal in Arabidopsis. Nat. Plants 1, 15073 (2015).","journal-title":"Nat. Plants"},{"key":"2438_CR41","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1038\/nchembio.2555","volume":"14","author":"N Uchida","year":"2018","unstructured":"Uchida, N. et al. Chemical hijacking of auxin signaling with an engineered auxin\u2013TIR1 pair. Nat. Chem. Biol. 14, 299\u2013305 (2018).","journal-title":"Nat. Chem. Biol."},{"key":"2438_CR42","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1146\/annurev-arplant-050312-120050","volume":"64","author":"N Geldner","year":"2013","unstructured":"Geldner, N. The endodermis. Annu. Rev. Plant Biol. 64, 531\u2013558 (2013).","journal-title":"Annu. Rev. Plant Biol."},{"key":"2438_CR43","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1104\/pp.114.244871","volume":"166","author":"NE Robbins","year":"2014","unstructured":"Robbins, N. E., Trontin, C., Duan, L. & Dinneny, J. R. Beyond the barrier: communication in the root though the endodermis. Plant Physiol. 166, 551\u2013559 (2014).","journal-title":"Plant Physiol."},{"key":"2438_CR44","doi-asserted-by":"publisher","first-page":"1395","DOI":"10.1016\/j.jplph.2007.08.002","volume":"164","author":"U Kutschera","year":"2007","unstructured":"Kutschera, U. & Niklas, K. J. The epidermal-growth-control theory of stem elongation: an old and a new perspective. J. Plant Physiol. 164, 1395\u20131409 (2007).","journal-title":"J. Plant Physiol."},{"key":"2438_CR45","doi-asserted-by":"publisher","first-page":"E4130","DOI":"10.1073\/pnas.1717649115","volume":"115","author":"II Vaseva","year":"2018","unstructured":"Vaseva, I. I. et al. The plant hormone ethylene restricts Arabidopsis growth via the epidermis. Proc. Natl Acad. Sci. USA 115, E4130\u2013E4139 (2018).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"2438_CR46","doi-asserted-by":"publisher","first-page":"613488","DOI":"10.3389\/fpls.2021.613488","volume":"12","author":"S Werner","year":"2021","unstructured":"Werner, S. et al. The cytokinin status of the epidermis regulates aspects of vegetative and reproductive development in Arabidopsis thaliana. Front. Plant Sci. 12, 613488 (2021).","journal-title":"Front. Plant Sci."},{"key":"2438_CR47","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1038\/s41477-021-01014-9","volume":"7","author":"Y Fridman","year":"2021","unstructured":"Fridman, Y. et al. The root meristem is shaped by brassinosteroid control of cell geometry. Nat. Plants 7, 1475\u20131484 (2021).","journal-title":"Nat. Plants"},{"key":"2438_CR48","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1038\/s41589-023-01447-7","volume":"20","author":"SY Park","year":"2024","unstructured":"Park, S. Y. et al. An orthogonalized PYR1-based CID module with reprogrammable ligand-binding specificity. Nat. Chem. Biol. 20, 103\u2013110 (2024).","journal-title":"Nat. Chem. Biol."},{"key":"2438_CR49","doi-asserted-by":"publisher","first-page":"1538","DOI":"10.1093\/pcp\/pcy127","volume":"59","author":"R Yamada","year":"2018","unstructured":"Yamada, R. et al. A super strong engineered auxin\u2013TIR1 pair. Plant Cell Physiol. 59, 1538\u20131544 (2018).","journal-title":"Plant Cell Physiol."},{"key":"2438_CR50","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1038\/nature05579","volume":"446","author":"D Loqu\u00e9","year":"2007","unstructured":"Loqu\u00e9, D., Lalonde, S., Looger, L. L., von Wir\u00e9n, N. & Frommer, W. B. A cytosolic trans-activation domain essential for ammonium uptake. Nature 446, 195\u2013198 (2007).","journal-title":"Nature"},{"key":"2438_CR51","doi-asserted-by":"publisher","first-page":"3416","DOI":"10.1105\/tpc.114.127571","volume":"26","author":"S Segami","year":"2014","unstructured":"Segami, S., Makino, S., Miyake, A., Asaoka, M. & Maeshima, M. Dynamics of vacuoles and H+-pyrophosphatase visualized by monomeric green fluorescent protein in Arabidopsis: artifactual bulbs and native intravacuolar spherical structures. Plant Cell 26, 3416\u20133434 (2014).","journal-title":"Plant Cell"},{"key":"2438_CR52","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1046\/j.1365-313x.1998.00343.x","volume":"16","author":"SJ Clough","year":"1998","unstructured":"Clough, S. J. & Bent, A. F. Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. Plant J. 16, 735\u2013743 (1998).","journal-title":"Plant J."},{"key":"2438_CR53","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.1111\/tpj.16699","volume":"118","author":"A Yoshinari","year":"2024","unstructured":"Yoshinari, A. et al. Near-infrared imaging of phytochrome-derived autofluorescence in plant nuclei. Plant J. 118, 1699\u20131712 (2024).","journal-title":"Plant J."},{"key":"2438_CR54","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/S0091-679X(08)85016-9","volume":"85","author":"S Shimozono","year":"2008","unstructured":"Shimozono, S. & Miyawaki, A. Engineering FRET constructs using CFP and YFP. Methods Cell Biol. 85, 381\u2013393 (2008).","journal-title":"Methods Cell Biol."},{"key":"2438_CR55","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.tplants.2005.01.008","volume":"10","author":"M Karimi","year":"2005","unstructured":"Karimi, M., Meyer, B. D. & Hilson, P. Modular cloning in plant cells. Trends Plant Sci. 10, 103\u2013105 (2005).","journal-title":"Trends Plant Sci."},{"key":"2438_CR56","doi-asserted-by":"publisher","first-page":"2303","DOI":"10.1242\/dev.060491","volume":"138","author":"S Miyashima","year":"2011","unstructured":"Miyashima, S., Koi, S., Hashimoto, T. & Nakajima, K. Non-cell-autonomous microRNA165 acts in a dose-dependent manner to regulate multiple differentiation status in the Arabidopsis root. Development 138, 2303\u20132313 (2011).","journal-title":"Development"},{"key":"2438_CR57","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1016\/0092-8674(84)90457-4","volume":"39","author":"D Kalderon","year":"1984","unstructured":"Kalderon, D., Roberts, B. L., Richardson, W. D. & Smith, A. E. A short amino acid sequence able to specify nuclear location. Cell 39, 499\u2013509 (1984).","journal-title":"Cell"},{"key":"2438_CR58","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1002\/jcc.21334","volume":"31","author":"O Trott","year":"2010","unstructured":"Trott, O. & Olson, A. J. AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J. Comput. Chem. 31, 455\u2013461 (2010).","journal-title":"J. Comput. Chem."},{"key":"2438_CR59","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1038\/s41586-021-03819-2","volume":"596","author":"J Jumper","year":"2021","unstructured":"Jumper, J. et al. Highly accurate protein structure prediction with AlphaFold. Nature 596, 583\u2013589 (2021).","journal-title":"Nature"},{"key":"2438_CR60","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/1758-2946-3-33","volume":"3","author":"NM O\u2019Boyle","year":"2011","unstructured":"O\u2019Boyle, N. M. et al. Open Babel: an open chemical toolbox. J. Cheminform. 3, 33 (2011).","journal-title":"J. Cheminform."},{"key":"2438_CR61","doi-asserted-by":"publisher","unstructured":"Eiki, M., Masayoshi, N. & Shinya, H. Docking model of mGID1 with sGA. Figshare https:\/\/doi.org\/10.6084\/m9.figshare.30655526 (2026).","DOI":"10.6084\/m9.figshare.30655526"}],"container-title":["Nature Plants"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41477-026-02438-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41477-026-02438-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41477-026-02438-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T09:01:40Z","timestamp":1792659700000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41477-026-02438-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,22]]},"references-count":61,"alternative-id":["2438"],"URL":"https:\/\/doi.org\/10.1038\/s41477-026-02438-x","relation":{},"ISSN":["2055-0278"],"issn-type":[{"value":"2055-0278","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,22]]},"assertion":[{"value":"19 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Ethics"}}]}}