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Investigating ICP in space has been challenging. We evaluated a telemetric lumbar ICP monitoring system that shows promise for investigating microgravity-induced intracranial pressure changes in astronauts. Despite limitations in pulse amplitude analysis and pressure underestimation, the system\u2019s long-term stability and overall performance support its recommendation for SANS research in space.<\/jats:p>","DOI":"10.1038\/s41526-026-00586-0","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T07:36:11Z","timestamp":1778571371000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Telemetric lumbar cerebrospinal fluid pressure monitoring for spaceflight: a novel approach to spaceflight-associated neuro-ocular syndrome research"],"prefix":"10.1038","volume":"12","author":[{"given":"Anders","family":"Eklund","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"B\u00e4cklund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Jan Malm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,7]]},"reference":[{"key":"586_CR1","doi-asserted-by":"publisher","first-page":"2058","DOI":"10.1016\/j.ophtha.2011.06.021","volume":"118","author":"TH Mader","year":"2011","unstructured":"Mader, T. 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