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Med."],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>National applications (apps) for adults with asthma were implemented as part of a respiratory toolkit across Wales from 2020. Data were collected on patient recorded asthma control including the Royal College of Physicians three questions. All general practices in Wales had patients registered on the asthma app and by September 2024, 12,567 (57.8%) of patients who downloaded the app went on to register. Analysis comparing baseline with four or more months of app use demonstrated improvements in the percent of those having a Royal College of Physicians asthma score of 0 (26.5% vs 40.7%, <jats:italic>p<\/jats:italic>\u2009=\u20090.0011), together with improvements in those not using a reliever inhaler at all (29.1% vs 39.2%, <jats:italic>p<\/jats:italic>\u2009=\u20090.0001). Where we had paired data one year apart, the improvements in asthma control were greater in those from most deprived areas. For those who used the app there were improvements across important metrics of asthma control consistent with better patient self-management.<\/jats:p>","DOI":"10.1038\/s41533-025-00433-x","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T12:49:29Z","timestamp":1749473369000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Creating expert patients: outcomes from a national digital therapeutic approach for people with asthma in Wales"],"prefix":"10.1038","volume":"35","author":[{"given":"Simon M.","family":"Barry","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Forton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gareth R.","family":"Davies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gwyneth A.","family":"Davies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie","family":"Pink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison","family":"Whittaker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerome","family":"Donagh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Menzies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Andrews","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grace","family":"Moore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Davies","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,6,9]]},"reference":[{"key":"433_CR1","unstructured":"Royal College of Physicians. 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Overuse of short-acting \u00df 2-agonists in asthma is associated with increased risk of exacerbation and mortality: a nationwide cohort study of the global SABINA programme. Eur Respir J. https:\/\/doi.org\/10.1183\/13993003.01872-2019 (2020).","DOI":"10.1183\/13993003.01872-2019"},{"key":"433_CR9","unstructured":"Digital Therapeutic Alliance. What is a DTx? - Digital Therapeutics Alliance (dtxalliance.org), (accessed 26th November 2024); https:\/\/dtxalliance.org."},{"key":"433_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.7861\/fhj.2022-0028","volume":"9","author":"R Jefferies","year":"2022","unstructured":"Jefferies, R., Ponsford, M. J., Davies, C., Williams, S. J. & Barry, S. Evaluating the implementation of a national COVID-19 hospital guideline in Wales. Future Healthc. J. 9, 1\u20136 (2022).","journal-title":"Future Healthc. J."},{"key":"433_CR11","first-page":"1","volume":"0","author":"SM Barry","year":"2023","unstructured":"Barry, S. M. et al. 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