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X.D. and C.Y.C. are inventors on a patent application titled \u2018Spiked Primer Design for Targeted Enrichment of Metagenomic Libraries\u2019 (US application no. 62\/667,344, filed 4 May 2018 by the University of California San Francisco) that includes a description of the methods and primer sets presented in this paper. A.A.A. is an employee of Karius, Inc.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}