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They also report having received royalty payments for inventions or discoveries related to cardiovascular diagnostics or therapeutics from Cleveland Heart Lab, a fully owned subsidiary of Quest Diagnostics, and Procter & Gamble. S.L.H. is a paid consultant for Procter & Gamble and Zehna Therapeutics, and has received research funds from Procter & Gamble, Pfizer Inc., Roche Diagnostics and Zehna Therapeutics. J.B. reports having received royalty payments from Procter & Gamble. G.F.G., M.F.C., D.B.C., K.L.W., B.R.L.G., H.J.D., P.H. and J.C.G.G. are employees of Procter & Gamble. W.H.W.T. reports being a consultant for Sequana Medical A.G., Owkin Inc, Relypsa Inc. and PreCardiac Inc., having received honoraria from Springer Nature for authorship\/editorship and the American Board of Internal Medicine for exam-writing committee participation\u2014all unrelated to the subject and contents of the present paper. The other authors declare that they have no relationships relevant to the contents of this paper to disclose.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}