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G.K.\u2019s brother, R. Kroemer, was an employee of Sanofi and now consults for Boehringer-Ingelheim. G.K.\u2019s wife, L. Zitvogel, has held research contracts with Glaxo Smyth Kline, Incyte, Lytix, Kaleido, Innovate Pharma, Daiichi Sankyo, Pilege, Merus, Transgene, 9m, Tusk and Roche; was on the on the Board of Directors of Transgene; is a co-founder of everImmune; and holds patents covering the treatment of cancer and the therapeutic manipulation of the microbiota. The other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}