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This work was supported by the intramural programme funds of the National Eye Institute (E.Y.C.). No industry support was used for this project. J.A.B. declares consulting for Jan One, Janssen and Novartis. J.S.S. declares having served as consultant for Alcon Laboratories, Boehringer Ingelheim, Dompe and Regeneron Pharmaceutical; having served as consultant and having received grant support from Bright Focus Foundation, National Eye Institute and Perfuse; having served as consultant and being a stockholder for AEYE Heath, Ocugenex, Ocular Therapeutix, Opticient and Tarus; having served as a consultant and having received royalties from Carl Zeiss Meditec, New York University School of Medicine, SLACKS, Tufts University School of Medicine and University of Pittsburgh Medical Center. W.H.W.T. has served as a consultant for Boston Scientific, CardiaTec Biosciences, Cardiol Therapeutics, Genomics, Intellia Therapeutics, Kiniksa Pharmaceuticals, Renovacor, Sequana Medical, WhiteSwell and Zehna Therapeutics, and has received honoraria from the American Board of Internal Medicine, Belvoir Media Group and Springer. The other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}