{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T13:26:50Z","timestamp":1794317210359,"version":"4.9.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:00:00Z","timestamp":1790899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:00:00Z","timestamp":1790899200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat Rev Endocrinol"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1038\/s41574-026-01311-3","type":"journal-article","created":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T11:37:44Z","timestamp":1790941064000},"page":"689-690","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of weight cycling in the presence and absence of obesity"],"prefix":"10.1038","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1312-7364","authenticated-orcid":false,"given":"Faidon","family":"Magkos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2186-9595","authenticated-orcid":false,"given":"Norbert","family":"Stefan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,2]]},"reference":[{"key":"1311_CR1","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.ypmed.2017.12.010","volume":"108","author":"CD Madigan","year":"2018","unstructured":"Madigan, C. D., Pavey, T., Daley, A. J., Jolly, K. & Brown, W. J. Is weight cycling associated with adverse health outcomes? A cohort study. Prev. Med. 108, 47\u201352 (2018).","journal-title":"Prev. Med."},{"key":"1311_CR2","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/j.molmet.2015.12.001","volume":"5","author":"J Schmitz","year":"2016","unstructured":"Schmitz, J. et al. Obesogenic memory can confer long-term increases in adipose tissue but not liver inflammation and insulin resistance after weight loss. Mol. Metab. 5, 328\u2013339 (2016).","journal-title":"Mol. Metab."},{"key":"1311_CR3","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1053\/meta.2002.29976","volume":"51","author":"T Kajioka","year":"2002","unstructured":"Kajioka, T., Tsuzuku, S., Shimokata, H. & Sato, Y. Effects of intentional weight cycling on non-obese young women. Metabolism 51, 149\u2013154 (2002).","journal-title":"Metabolism"},{"key":"1311_CR4","first-page":"367","volume":"15","author":"SA Jebb","year":"1991","unstructured":"Jebb, S. A., Goldberg, G. R., Coward, W. A., Murgatroyd, P. R. & Prentice, A. M. Effects of weight cycling caused by intermittent dieting on metabolic rate and body composition in obese women. Int. J. Obes. 15, 367\u2013374 (1991).","journal-title":"Int. J. Obes."},{"key":"1311_CR5","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1002\/j.1550-8528.1999.tb00720.x","volume":"7","author":"M Elia","year":"1999","unstructured":"Elia, M., Stubbs, R. J. & Henry, C. J. Differences in fat, carbohydrate, and protein metabolism between lean and obese subjects undergoing total starvation. Obes. Res. 7, 597\u2013604 (1999).","journal-title":"Obes. Res."},{"key":"1311_CR6","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1016\/S2213-8587(26)00037-9","volume":"14","author":"F Magkos","year":"2026","unstructured":"Magkos, F. & Stefan, N. Is weight cycling clinically harmful? Lancet Diabetes Endocrinol. 14, 594\u2013607 (2026).","journal-title":"Lancet Diabetes Endocrinol."},{"key":"1311_CR7","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1079\/PNS19910055","volume":"50","author":"AM Prentice","year":"1991","unstructured":"Prentice, A. M. et al. Physiological responses to slimming. Proc. Nutr. Soc. 50, 441\u2013458 (1991).","journal-title":"Proc. Nutr. Soc."},{"key":"1311_CR8","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1001\/archinte.1994.00420120035004","volume":"154","author":"KD Brownell","year":"1994","unstructured":"Brownell, K. D. & Rodin, J. Medical, metabolic, and psychological effects of weight cycling. Arch. Intern. Med. 154, 1325\u20131330 (1994).","journal-title":"Arch. Intern. Med."},{"key":"1311_CR9","doi-asserted-by":"publisher","first-page":"577","DOI":"10.3389\/fpsyg.2013.00577","volume":"4","author":"MR Lowe","year":"2013","unstructured":"Lowe, M. R., Doshi, S. D., Katterman, S. N. & Feig, E. H. Dieting and restrained eating as prospective predictors of weight gain. Front. Psychol. 4, 577 (2013).","journal-title":"Front. Psychol."},{"key":"1311_CR10","doi-asserted-by":"publisher","first-page":"101682","DOI":"10.1016\/j.eatbeh.2022.101682","volume":"47","author":"Y Zhong","year":"2022","unstructured":"Zhong, Y., McGuire, F. H. & Duncan, A. E. Who is trying to lose weight? Trends and prevalence in past-year weight loss attempts among US adults 1999-2018 at the intersection of race\/ethnicity, gender, and weight status. Eat. Behav. 47, 101682 (2022).","journal-title":"Eat. Behav."}],"container-title":["Nature Reviews Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41574-026-01311-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41574-026-01311-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41574-026-01311-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T13:03:33Z","timestamp":1794315813000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41574-026-01311-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,2]]},"references-count":10,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["1311"],"URL":"https:\/\/doi.org\/10.1038\/s41574-026-01311-3","relation":{},"ISSN":["1759-5029","1759-5037"],"issn-type":[{"value":"1759-5029","type":"print"},{"value":"1759-5037","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,2]]},"assertion":[{"value":"2 October 2026","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"F.M. reports fees for consultancy from AstraZeneca in 2025. N.S. reports fees for consultancy and scientific talks from AstraZeneca, Boehringer Ingelheim, Lilly, Novo Nordisk, Pfizer and Sanofi. N.S. has received research support from AstraZeneca, Boehringer Ingelheim and Sanofi.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Ethics"}}]}}