{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:47:29Z","timestamp":1785804449013,"version":"3.56.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T00:00:00Z","timestamp":1596585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T00:00:00Z","timestamp":1596585600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat Rev Gastroenterol Hepatol"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1038\/s41575-020-0356-y","type":"journal-article","created":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T15:03:46Z","timestamp":1596639826000},"page":"651-652","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Non-canonical cholinergic anti-inflammatory pathway in IBD"],"prefix":"10.1038","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2656-4077","authenticated-orcid":false,"given":"Alan","family":"de Araujo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0032-8810","authenticated-orcid":false,"given":"Guillaume","family":"de Lartigue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,8,5]]},"reference":[{"key":"356_CR1","doi-asserted-by":"publisher","first-page":"5791","DOI":"10.1113\/JP271538","volume":"594","author":"G de Lartigue","year":"2016","unstructured":"de Lartigue, G. Role of the vagus nerve in the development and treatment of diet-induced obesity. J. Physiol. 594, 5791\u20135815 (2016).","journal-title":"J. Physiol."},{"key":"356_CR2","doi-asserted-by":"publisher","DOI":"10.1159\/000504474","author":"W Lei","year":"2019","unstructured":"Lei, W. & Duan, Z. Advances in the treatment of cholinergic anti-inflammatory pathways in gastrointestinal diseases by electrical stimulation of vagus nerve. Digestion https:\/\/doi.org\/10.1159\/000504474 (2019).","journal-title":"Digestion"},{"key":"356_CR3","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2425-3","author":"T Teratani","year":"2020","unstructured":"Teratani, T. et al. The liver\u2013brain\u2013gut neural arc maintains the Treg cell niche in the gut. Nature https:\/\/doi.org\/10.1038\/s41586-020-2425-3 (2020).","journal-title":"Nature"},{"key":"356_CR4","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1002\/ar.a.20088","volume":"280","author":"HR Berthoud","year":"2004","unstructured":"Berthoud, H. R. Anatomy and function of sensory hepatic nerves. Anat. Rec. A Discov. Mol. Cell Evol. Biol. 280, 827\u2013835 (2004).","journal-title":"Anat. Rec. A Discov. Mol. Cell Evol. Biol."},{"key":"356_CR5","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1002\/hep.26494","volume":"59","author":"B Chassaing","year":"2014","unstructured":"Chassaing, B., Etienne-Mesmin, L. & Gewirtz, A. T. Microbiota-liver axis in hepatic disease. Hepatology 59, 328\u2013339 (2014).","journal-title":"Hepatology"},{"key":"356_CR6","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1016\/j.cell.2018.08.049","volume":"175","author":"W Han","year":"2018","unstructured":"Han, W. et al. A neural circuit for gut-induced reward. Cell 175, 665\u2013678 (2018).","journal-title":"Cell"},{"key":"356_CR7","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13288","author":"K Murray","year":"2018","unstructured":"Murray, K. & Reardon, C. The cholinergic anti-inflammatory pathway revisited. Neurogastroenterol. Motil. https:\/\/doi.org\/10.1111\/nmo.13288 (2018).","journal-title":"Neurogastroenterol. Motil."},{"key":"356_CR8","first-page":"R200","volume":"260","author":"HR Berthoud","year":"1991","unstructured":"Berthoud, H. R., Carlson, N. R. & Powley, T. L. Topography of efferent vagal innervation of the rat gastrointestinal tract. Am. J. Physiol. 260, R200\u2013207 (1991).","journal-title":"Am. J. Physiol."},{"key":"356_CR9","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-320789","author":"B Zhang","year":"2020","unstructured":"Zhang, B. et al. Inflammatory bowel disease is associated with higher dementia risk: a nationwide longitudinal study. Gut https:\/\/doi.org\/10.1136\/gutjnl-2020-320789 (2020).","journal-title":"Gut"},{"key":"356_CR10","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1021\/acschemneuro.9b00607","volume":"11","author":"P Fu","year":"2020","unstructured":"Fu, P., Gao, M. & Yung, K. K. L. Association of intestinal disorders with Parkinson\u2019s disease and Alzheimer\u2019s disease: a systematic review and meta-analysis. ACS Chem. Neurosci. 11, 395\u2013405 (2020).","journal-title":"ACS Chem. Neurosci."}],"container-title":["Nature Reviews Gastroenterology &amp; Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41575-020-0356-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41575-020-0356-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41575-020-0356-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,4]],"date-time":"2021-08-04T23:32:42Z","timestamp":1628119962000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41575-020-0356-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,5]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["356"],"URL":"https:\/\/doi.org\/10.1038\/s41575-020-0356-y","relation":{},"ISSN":["1759-5045","1759-5053"],"issn-type":[{"value":"1759-5045","type":"print"},{"value":"1759-5053","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,5]]},"assertion":[{"value":"5 August 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}