{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T12:49:52Z","timestamp":1782218992816,"version":"3.54.5"},"reference-count":2,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat. Rev. Neurosci."],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1038\/s41583-026-01050-4","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T12:43:00Z","timestamp":1778589780000},"page":"462-462","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mapping the molecular effects of Down syndrome in the developing brain"],"prefix":"10.1038","volume":"27","author":[{"given":"Katherine","family":"Whalley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,12]]},"reference":[{"key":"1050_CR1","doi-asserted-by":"publisher","first-page":"eaea1259","DOI":"10.1126\/science.aea1259","volume":"392","author":"CK Vuong","year":"2026","unstructured":"Vuong, C. K. et al. A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortex. Science 392, eaea1259 (2026)","journal-title":"Science"},{"key":"1050_CR2","doi-asserted-by":"publisher","first-page":"eaea1549","DOI":"10.1126\/science.aea1549","volume":"392","author":"RD Risgaard","year":"2026","unstructured":"Risgaard, R. D. et al. Molecular and cellular processes disrupted in the early postnatal Down syndrome prefrontal cortex. Science 392, eaea1549 (2026)","journal-title":"Science"}],"container-title":["Nature Reviews Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41583-026-01050-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41583-026-01050-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41583-026-01050-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T12:03:15Z","timestamp":1782216195000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41583-026-01050-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,12]]},"references-count":2,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["1050"],"URL":"https:\/\/doi.org\/10.1038\/s41583-026-01050-4","relation":{},"ISSN":["1471-003X","1471-0048"],"issn-type":[{"value":"1471-003X","type":"print"},{"value":"1471-0048","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,12]]},"assertion":[{"value":"12 May 2026","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}