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V.M.H. declares acting as a current or recent consultant to BMS, Celgene, Janssen R&D, and Q32 Bio, and support from research grants from Janssen R&D and Q32 Bio. S.O. declares receipt of consultancy or speaker fees from Novartis and Sobi. N.R. declares receipt of honoraria for consultancies or speaker bureaus in the past 3 years from Ablynx, AstraZeneca\/MedImmune, Biogen, BMS, Boehringer Ingelheim, Eli Lilly, EMD Serono, F. Hoffmann-La Roche, GSK, Janssen, Merck Sharp & Dohme, Novartis, Pfizer, R-Pharm, Sanofi, Servier, Sinergie, and Sobi. The IRCCS Istituto Giannina Gaslini, where N.R. works as a full-time public employee, has received contributions in the past 3 years from BMS, Eli Lilly, F. Hoffmann-La Roche, GSK, Janssen, Novartis, Pfizer, and Sobi. This funding has been reinvested for the research activities of the hospital in a fully independent manner, without any commitment with third parties. L.R.W. declares support from AbbVie, GSK, Pfizer, Sobi, and UCB to the CLUSTER Consortium. R.S.M.Y. declares one-time consulting fees from Eli-Lilly and Novartis. A.M. declares receipt of honoraria for consultancies from Aurinia, BMS, Eli-Lilly, EMD Serono, Janssen, and Pfizer. All other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}