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Hoffmann-La Roche. K.M.S. has consulting agreements for the following companies, which involve monetary and\/or stock compensation: Black Diamond Therapeutics, BridGene Biosciences, Denali Therapeutics, Dice Molecules, eFFECTOR Therapeutics (zotatifin and tomivosertib), Erasca, Genentech\/Roche, Janssen Pharmaceuticals, Kumquat Biosciences, Kura Oncology, Merck, Mitokinin, Petra Pharma, Qulab, Revolution Medicines (WDB002), Type6 Therapeutics, Venthera, Wellspring Biosciences (Araxes Pharma). J.T. is a cofounder and shareholder of Global Blood Therapeutics, Principia Biopharma, Kezar Life Sciences and Cedilla Therapeutics. J.T. and P.P.S. are listed as inventors on a patent application that describes the cyclic depsipeptide, PS3061 (PCT\/US2019\/024731 by the Regents of the University of California and Kezar Life Sciences). D.R. is a shareholder of eFFECTOR Therapeutics and a member of its scientific advisory board (zotatifin and tomivosertib). C.S.C. is a co-founder of Catalyst Biosciences and Alaunus Biosciences, and receives grant\/research support from ShangPharma\/ChemPartners. A.A. is a co-founder of Tango Therapeutics, Azkarra Therapeutics, Ovibio Corporation; a consultant for SPARC, Bluestar, ProLynx, Earli, Cura, GenVivo and GSK; a member of the SAB of Genentech and GLAdiator; receives grant\/research support from SPARC and AstraZeneca; holds patents on the use of PARP inhibitors held jointly with AstraZeneca, from which he has benefitted financially (and may do so in the future). The authors have not filed for patent protection on the SARS-CoV-2 host interactions or the use of predicted drugs for the treatment of COVID-19 to ensure all of the information is freely available to accelerate the discovery of a treatment.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}