{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T23:37:59Z","timestamp":1792280279598,"version":"4.4.0"},"reference-count":65,"publisher":"Springer Science and Business Media LLC","issue":"8011","license":[{"start":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T00:00:00Z","timestamp":1712707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T00:00:00Z","timestamp":1712707200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nature"],"published-print":{"date-parts":[[2024,5,9]]},"DOI":"10.1038\/s41586-024-07292-5","type":"journal-article","created":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T12:01:48Z","timestamp":1712750508000},"page":"384-392","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":63,"title":["Cell-type-resolved mosaicism reveals clonal dynamics of the human forebrain"],"prefix":"10.1038","volume":"629","author":[{"given":"Changuk","family":"Chung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0219-0023","authenticated-orcid":false,"given":"Xiaoxu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert F.","family":"Hevner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5377-9845","authenticated-orcid":false,"given":"Keng Ioi","family":"Vong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arzoo","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Nedunuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott T.","family":"Barton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2192-7756","authenticated-orcid":false,"given":"Geoffroy","family":"Noel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8106-9446","authenticated-orcid":false,"given":"Chelsea","family":"Barrows","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Stanley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swapnil","family":"Mittal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin W.","family":"Breuss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7801-9743","authenticated-orcid":false,"given":"Johannes C. M.","family":"Schlachetzki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen F.","family":"Kingsmore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0889-9220","authenticated-orcid":false,"given":"Joseph G.","family":"Gleeson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,10]]},"reference":[{"key":"7292_CR1","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1126\/science.278.5337.474","volume":"278","author":"SA Anderson","year":"1997","unstructured":"Anderson, S. A., Eisenstat, D. D., Shi, L. & Rubenstein, J. L. Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes. Science 278, 474\u2013476 (1997).","journal-title":"Science"},{"key":"7292_CR2","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1038\/nature00779","volume":"417","author":"K Letinic","year":"2002","unstructured":"Letinic, K., Zoncu, R. & Rakic, P. Origin of GABAergic neurons in the human neocortex. Nature 417, 645\u2013649 (2002).","journal-title":"Nature"},{"key":"7292_CR3","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1038\/nrn1954","volume":"7","author":"CP Wonders","year":"2006","unstructured":"Wonders, C. P. & Anderson, S. A. The origin and specification of cortical interneurons. Nat. Rev. Neurosci. 7, 687\u2013696 (2006).","journal-title":"Nat. Rev. Neurosci."},{"key":"7292_CR4","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1093\/cercor\/bhn078","volume":"19","author":"Z Petanjek","year":"2009","unstructured":"Petanjek, Z., Berger, B. & Esclapez, M. Origins of cortical GABAergic neurons in the cynomolgus monkey. Cereb. Cortex 19, 249\u2013262 (2009).","journal-title":"Cereb. Cortex"},{"key":"7292_CR5","doi-asserted-by":"publisher","first-page":"1576","DOI":"10.1038\/nn.3541","volume":"16","author":"DV Hansen","year":"2013","unstructured":"Hansen, D. V. et al. Non-epithelial stem cells and cortical interneuron production in the human ganglionic eminences. Nat. Neurosci. 16, 1576\u20131587 (2013).","journal-title":"Nat. Neurosci."},{"key":"7292_CR6","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1038\/s41586-021-04230-7","volume":"601","author":"RN Delgado","year":"2022","unstructured":"Delgado, R. N. et al. Individual human cortical progenitors can produce excitatory and inhibitory neurons. Nature 601, 397\u2013403 (2022).","journal-title":"Nature"},{"key":"7292_CR7","doi-asserted-by":"publisher","first-page":"1382","DOI":"10.1016\/j.stem.2023.08.009","volume":"30","author":"MG Andrews","year":"2023","unstructured":"Andrews, M. G. et al. LIF signaling regulates outer radial glial to interneuron fate during human cortical development. Cell Stem Cell 30, 1382\u20131391.e5 (2023).","journal-title":"Cell Stem Cell"},{"key":"7292_CR8","doi-asserted-by":"publisher","first-page":"3155","DOI":"10.1523\/JNEUROSCI.13-07-03155.1993","volume":"13","author":"A Bulfone","year":"1993","unstructured":"Bulfone, A. et al. Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J. Neurosci. 13, 3155\u20133172 (1993).","journal-title":"J. Neurosci."},{"key":"7292_CR9","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/S0166-2236(03)00234-0","volume":"26","author":"L Puelles","year":"2003","unstructured":"Puelles, L. & Rubenstein, J. L. Forebrain gene expression domains and the evolving prosomeric model. Trends Neurosci. 26, 469\u2013476 (2003).","journal-title":"Trends Neurosci."},{"key":"7292_CR10","doi-asserted-by":"publisher","first-page":"2203","DOI":"10.1242\/dev.124.11.2203","volume":"124","author":"Y Furuta","year":"1997","unstructured":"Furuta, Y., Piston, D. W. & Hogan, B. L. Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development. Development 124, 2203\u20132212 (1997).","journal-title":"Development"},{"key":"7292_CR11","doi-asserted-by":"publisher","first-page":"2315","DOI":"10.1242\/dev.125.12.2315","volume":"125","author":"EA Grove","year":"1998","unstructured":"Grove, E. A., Tole, S., Limon, J., Yip, L. & Ragsdale, C. W. The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice. Development 125, 2315\u20132325 (1998).","journal-title":"Development"},{"key":"7292_CR12","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1016\/S0896-6273(01)00504-9","volume":"32","author":"ES Monuki","year":"2001","unstructured":"Monuki, E. S., Porter, F. D. & Walsh, C. A. Patterning of the dorsal telencephalon and cerebral cortex by a roof plate-Lhx2 pathway. Neuron 32, 591\u2013604 (2001).","journal-title":"Neuron"},{"key":"7292_CR13","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1038\/s41586-021-04237-0","volume":"601","author":"RC Bandler","year":"2022","unstructured":"Bandler, R. C. et al. Single-cell delineation of lineage and genetic identity in the mouse brain. Nature 601, 404\u2013409 (2022).","journal-title":"Nature"},{"key":"7292_CR14","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1038\/s41593-022-01011-x","volume":"25","author":"M Ratz","year":"2022","unstructured":"Ratz, M. et al. Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics. Nat. Neurosci. 25, 285\u2013294 (2022).","journal-title":"Nat. Neurosci."},{"key":"7292_CR15","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1002\/pros.2990090108","volume":"9","author":"H Dang","year":"1986","unstructured":"Dang, H. et al. Monoclonal antibody specific to acid phosphatase isoenzyme 4. Prostate 9, 47\u201355 (1986).","journal-title":"Prostate"},{"key":"7292_CR16","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1126\/science.abe1544","volume":"371","author":"S Bizzotto","year":"2021","unstructured":"Bizzotto, S. et al. Landmarks of human embryonic development inscribed in somatic mutations. Science 371, 1249\u20131253 (2021).","journal-title":"Science"},{"key":"7292_CR17","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1038\/s41586-022-04602-7","volume":"604","author":"MW Breuss","year":"2022","unstructured":"Breuss, M. W. et al. Somatic mosaicism reveals clonal distributions of neocortical development. Nature 604, 689\u2013696 (2022).","journal-title":"Nature"},{"key":"7292_CR18","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1038\/s41586-021-03786-8","volume":"597","author":"S Park","year":"2021","unstructured":"Park, S. et al. Clonal dynamics in early human embryogenesis inferred from somatic mutation. Nature 597, 393\u2013397 (2021).","journal-title":"Nature"},{"key":"7292_CR19","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1002\/cne.901450105","volume":"145","author":"P Rakic","year":"1972","unstructured":"Rakic, P. Mode of cell migration to the superficial layers of fetal monkey neocortex. J. Comp. Neurol. 145, 61\u201383 (1972).","journal-title":"J. Comp. Neurol."},{"key":"7292_CR20","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1016\/j.tins.2004.05.001","volume":"27","author":"AR Kriegstein","year":"2004","unstructured":"Kriegstein, A. R. & Noctor, S. C. Patterns of neuronal migration in the embryonic cortex. Trends Neurosci. 27, 392\u2013399 (2004).","journal-title":"Trends Neurosci."},{"key":"7292_CR21","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1038\/nrn2719","volume":"10","author":"P Rakic","year":"2009","unstructured":"Rakic, P. Evolution of the neocortex: a perspective from developmental biology. Nat. Rev. Neurosci. 10, 724\u2013735 (2009).","journal-title":"Nat. Rev. Neurosci."},{"key":"7292_CR22","doi-asserted-by":"publisher","first-page":"3759","DOI":"10.1242\/dev.128.19.3759","volume":"128","author":"H Wichterle","year":"2001","unstructured":"Wichterle, H., Turnbull, D. H., Nery, S., Fishell, G. & Alvarez-Buylla, A. In utero fate mapping reveals distinct migratory pathways and fates of neurons born in the mammalian basal forebrain. Development 128, 3759\u20133771 (2001).","journal-title":"Development"},{"key":"7292_CR23","doi-asserted-by":"publisher","first-page":"1588","DOI":"10.1038\/nn.3536","volume":"16","author":"T Ma","year":"2013","unstructured":"Ma, T. et al. Subcortical origins of human and monkey neocortical interneurons. Nat. Neurosci. 16, 1588\u20131597 (2013).","journal-title":"Nat. Neurosci."},{"key":"7292_CR24","doi-asserted-by":"publisher","first-page":"2242","DOI":"10.1093\/cercor\/bhv074","volume":"26","author":"A Arshad","year":"2016","unstructured":"Arshad, A. et al. Extended production of cortical interneurons into the third trimester of human gestation. Cereb. Cortex 26, 2242\u20132256 (2016).","journal-title":"Cereb. Cortex"},{"key":"7292_CR25","doi-asserted-by":"publisher","first-page":"4971","DOI":"10.1093\/cercor\/bhx185","volume":"27","author":"A Alzu\u2019bi","year":"2017","unstructured":"Alzu\u2019bi, A. et al. The transcription factors COUP-TFI and COUP-TFII have distinct roles in arealisation and GABAergic interneuron specification in the early human fetal relencephalon. Cereb. Cortex 27, 4971\u20134987 (2017).","journal-title":"Cereb. Cortex"},{"key":"7292_CR26","doi-asserted-by":"publisher","first-page":"2309","DOI":"10.1007\/s00429-016-1343-5","volume":"222","author":"A Alzu\u2019bi","year":"2017","unstructured":"Alzu\u2019bi, A. et al. Distinct cortical and sub-cortical neurogenic domains for GABAergic interneuron precursor transcription factors NKX2.1, OLIG2 and COUP-TFII in early fetal human telencephalon. Brain Struct. Funct. 222, 2309\u20132328 (2017).","journal-title":"Brain Struct. Funct."},{"key":"7292_CR27","doi-asserted-by":"publisher","unstructured":"Marks, J. R. et al. Unifying comprehensive genomics and transcriptomics in individual cells to illuminate oncogenic and drug resistance mechanisms. Preprint at bioRxiv https:\/\/doi.org\/10.1101\/2022.04.29.489440 (2023).","DOI":"10.1101\/2022.04.29.489440"},{"key":"7292_CR28","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1126\/science.aao4426","volume":"359","author":"MA Lodato","year":"2018","unstructured":"Lodato, M. A. et al. Aging and neurodegeneration are associated with increased mutations in single human neurons. Science 359, 555\u2013559 (2018).","journal-title":"Science"},{"key":"7292_CR29","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1038\/s41593-020-00765-6","volume":"24","author":"RE Rodin","year":"2021","unstructured":"Rodin, R. E. et al. The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing. Nat. Neurosci. 24, 176\u2013185 (2021).","journal-title":"Nat. Neurosci."},{"key":"7292_CR30","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1016\/j.cell.2014.01.044","volume":"156","author":"A Ernst","year":"2014","unstructured":"Ernst, A. et al. Neurogenesis in the striatum of the adult human brain. Cell 156, 1072\u20131083 (2014).","journal-title":"Cell"},{"key":"7292_CR31","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1126\/science.aan3351","volume":"357","author":"C Luo","year":"2017","unstructured":"Luo, C. et al. Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex. Science 357, 600\u2013604 (2017).","journal-title":"Science"},{"key":"7292_CR32","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1038\/nature21703","volume":"543","author":"YS Ju","year":"2017","unstructured":"Ju, Y. S. et al. Somatic mutations reveal asymmetric cellular dynamics in the early human embryo. Nature 543, 714\u2013718 (2017).","journal-title":"Nature"},{"key":"7292_CR33","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1126\/science.abe0981","volume":"371","author":"L Fasching","year":"2021","unstructured":"Fasching, L. et al. Early developmental asymmetries in cell lineage trees in living individuals. Science 371, 1245\u20131248 (2021).","journal-title":"Science"},{"key":"7292_CR34","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1038\/s41593-018-0176-3","volume":"21","author":"F Ginhoux","year":"2018","unstructured":"Ginhoux, F. & Garel, S. The mysterious origins of microglia. Nat. Neurosci. 21, 897\u2013899 (2018).","journal-title":"Nat. Neurosci."},{"key":"7292_CR35","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.cell.2019.08.053","volume":"179","author":"M Prinz","year":"2019","unstructured":"Prinz, M., Jung, S. & Priller, J. Microglia biology: one century of evolving concepts. Cell 179, 292\u2013311 (2019).","journal-title":"Cell"},{"key":"7292_CR36","doi-asserted-by":"publisher","first-page":"e2119281119","DOI":"10.1073\/pnas.2119281119","volume":"119","author":"E Gilbert","year":"2022","unstructured":"Gilbert, E., Shanmugam, A. & Cavalleri, G. L. Revealing the recent demographic history of Europe via haplotype sharing in the UK Biobank. Proc. Natl Acad. Sci. USA 119, e2119281119 (2022).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"7292_CR37","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1038\/s10038-020-00851-4","volume":"66","author":"A Diaz-Papkovich","year":"2021","unstructured":"Diaz-Papkovich, A., Anderson-Trocme, L. & Gravel, S. A review of UMAP in population genetics. J. Hum. Genet. 66, 85\u201391 (2021).","journal-title":"J. Hum. Genet."},{"key":"7292_CR38","doi-asserted-by":"publisher","first-page":"2612","DOI":"10.1523\/JNEUROSCI.5667-03.2004","volume":"24","author":"Q Xu","year":"2004","unstructured":"Xu, Q., Cobos, I., De La Cruz, E., Rubenstein, J. L. & Anderson, S. A. Origins of cortical interneuron subtypes. J. Neurosci. 24, 2612\u20132622 (2004).","journal-title":"J. Neurosci."},{"key":"7292_CR39","doi-asserted-by":"publisher","first-page":"1582","DOI":"10.1523\/JNEUROSCI.4515-09.2010","volume":"30","author":"G Miyoshi","year":"2010","unstructured":"Miyoshi, G. et al. Genetic fate mapping reveals that the caudal ganglionic eminence produces a large and diverse population of superficial cortical interneurons. J. Neurosci. 30, 1582\u20131594 (2010).","journal-title":"J. Neurosci."},{"key":"7292_CR40","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1016\/j.neuron.2015.07.011","volume":"87","author":"C Mayer","year":"2015","unstructured":"Mayer, C. et al. Clonally related forebrain interneurons disperse broadly across both functional areas and structural boundaries. Neuron 87, 989\u2013998 (2015).","journal-title":"Neuron"},{"key":"7292_CR41","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1038\/s41586-019-1506-7","volume":"573","author":"RD Hodge","year":"2019","unstructured":"Hodge, R. D. et al. Conserved cell types with divergent features in human versus mouse cortex. Nature 573, 61\u201368 (2019).","journal-title":"Nature"},{"key":"7292_CR42","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1038\/s41586-018-0654-5","volume":"563","author":"B Tasic","year":"2018","unstructured":"Tasic, B. et al. Shared and distinct transcriptomic cell types across neocortical areas. Nature 563, 72\u201378 (2018).","journal-title":"Nature"},{"key":"7292_CR43","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/0925-4773(93)90012-M","volume":"44","author":"G Oliver","year":"1993","unstructured":"Oliver, G. et al. Prox 1, a prospero-related homeobox gene expressed during mouse development. Mech. Dev. 44, 3\u201316 (1993).","journal-title":"Mech. Dev."},{"key":"7292_CR44","doi-asserted-by":"publisher","first-page":"2403","DOI":"10.1242\/dev.125.13.2403","volume":"125","author":"C LaBonne","year":"1998","unstructured":"LaBonne, C. & Bronner-Fraser, M. Neural crest induction in Xenopus: evidence for a two-signal model. Development 125, 2403\u20132414 (1998).","journal-title":"Development"},{"key":"7292_CR45","doi-asserted-by":"publisher","first-page":"13713","DOI":"10.1073\/pnas.94.25.13713","volume":"94","author":"JP Saint-Jeannet","year":"1997","unstructured":"Saint-Jeannet, J. P., He, X., Varmus, H. E. & Dawid, I. B. Regulation of dorsal fate in the neuraxis by Wnt-1 and Wnt-3a. Proc. Natl Acad. Sci. USA 94, 13713\u201313718 (1997).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"7292_CR46","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1006\/dbio.2002.0579","volume":"244","author":"S Faure","year":"2002","unstructured":"Faure, S., de Santa Barbara, P., Roberts, D. J. & Whitman, M. Endogenous patterns of BMP signaling during early chick development. Dev. Biol. 244, 44\u201365 (2002).","journal-title":"Dev. Biol."},{"key":"7292_CR47","doi-asserted-by":"publisher","first-page":"3715","DOI":"10.1007\/s00018-012-0991-8","volume":"69","author":"TJ Stuhlmiller","year":"2012","unstructured":"Stuhlmiller, T. J. & Garcia-Castro, M. I. Current perspectives of the signaling pathways directing neural crest induction. Cell. Mol. Life Sci. 69, 3715\u20133737 (2012).","journal-title":"Cell. Mol. Life Sci."},{"key":"7292_CR48","doi-asserted-by":"crossref","unstructured":"Bingman, V. P., Salas, C. & Rodriguez, F. in Encyclopedia of Neuroscience (eds Binder, M. D., Hirokawa, N. & Windhorst, U.) 1356\u20131360 (Springer Berlin Heidelberg, 2009).","DOI":"10.1007\/978-3-540-29678-2_3158"},{"key":"7292_CR49","doi-asserted-by":"publisher","first-page":"5425","DOI":"10.1113\/jphysiol.2012.246660","volume":"591","author":"S Grillner","year":"2013","unstructured":"Grillner, S., Robertson, B. & Stephenson-Jones, M. The evolutionary origin of the vertebrate basal ganglia and its role in action selection. J. Physiol. 591, 5425\u20135431 (2013).","journal-title":"J. Physiol."},{"key":"7292_CR50","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1016\/j.cub.2011.05.001","volume":"21","author":"M Stephenson-Jones","year":"2011","unstructured":"Stephenson-Jones, M., Samuelsson, E., Ericsson, J., Robertson, B. & Grillner, S. Evolutionary conservation of the basal ganglia as a common vertebrate mechanism for action selection. Curr. Biol. 21, 1081\u20131091 (2011).","journal-title":"Curr. Biol."},{"key":"7292_CR51","doi-asserted-by":"publisher","unstructured":"Sepulveda, W., Sepulveda, F., Schonstedt, V., Stern, J. & Diaz-Serani, R. Neuroimaging findings in fetal hemimegalencephaly: case study and review. Fetal Diagn. Ther. https:\/\/doi.org\/10.1159\/000535406 (2023).","DOI":"10.1159\/000535406"},{"key":"7292_CR52","doi-asserted-by":"publisher","unstructured":"Chung, C. et al. shishenyxx\/Human_Inhibitory_Neurons: 1.0.1. Zenodo https:\/\/doi.org\/10.5281\/ZENODO.10772159 (2024).","DOI":"10.5281\/ZENODO.10772159"},{"key":"7292_CR53","doi-asserted-by":"publisher","first-page":"e76","DOI":"10.1093\/nar\/gkx024","volume":"45","author":"AY Huang","year":"2017","unstructured":"Huang, A. Y. et al. MosaicHunter: accurate detection of postzygotic single-nucleotide mosaicism through next-generation sequencing of unpaired, trio, and paired samples. Nucleic Acids Res. 45, e76 (2017).","journal-title":"Nucleic Acids Res."},{"key":"7292_CR54","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1038\/s41591-019-0711-0","volume":"26","author":"MW Breuss","year":"2020","unstructured":"Breuss, M. W. et al. Autism risk in offspring can be assessed through quantification of male sperm mosaicism. Nat. Med. 26, 143\u2013150 (2020).","journal-title":"Nat. Med."},{"key":"7292_CR55","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1038\/nbt.2514","volume":"31","author":"K Cibulskis","year":"2013","unstructured":"Cibulskis, K. et al. Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. Nat. Biotechnol. 31, 213\u2013219 (2013).","journal-title":"Nat. Biotechnol."},{"key":"7292_CR56","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1038\/s41587-022-01559-w","volume":"41","author":"X Yang","year":"2023","unstructured":"Yang, X. et al. Control-independent mosaic single nucleotide variant detection with DeepMosaic. Nat. Biotechnol. 41, 870\u2013877 (2023).","journal-title":"Nat. Biotechnol."},{"key":"7292_CR57","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1038\/s41587-019-0368-8","volume":"38","author":"Y Dou","year":"2020","unstructured":"Dou, Y. et al. Accurate detection of mosaic variants in sequencing data without matched controls. Nat. Biotechnol. 38, 314\u2013319 (2020).","journal-title":"Nat. Biotechnol."},{"key":"7292_CR58","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1038\/s41592-018-0051-x","volume":"15","author":"S Kim","year":"2018","unstructured":"Kim, S. et al. Strelka2: fast and accurate calling of germline and somatic variants. Nat. Methods 15, 591\u2013594 (2018).","journal-title":"Nat. Methods"},{"key":"7292_CR59","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1038\/s41586-020-2308-7","volume":"581","author":"KJ Karczewski","year":"2020","unstructured":"Karczewski, K. J. et al. The mutational constraint spectrum quantified from variation in 141,456 humans. Nature 581, 434\u2013443 (2020).","journal-title":"Nature"},{"key":"7292_CR60","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1126\/science.aay0793","volume":"366","author":"A Nott","year":"2019","unstructured":"Nott, A. et al. Brain cell type-specific enhancer\u2013promoter interactome maps and disease-risk association. Science 366, 1134\u20131139 (2019).","journal-title":"Science"},{"key":"7292_CR61","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1093\/bioinformatics\/btr167","volume":"27","author":"F Krueger","year":"2011","unstructured":"Krueger, F. & Andrews, S. R. Bismark: a flexible aligner and methylation caller for Bisulfite-seq applications. Bioinformatics 27, 1571\u20131572 (2011).","journal-title":"Bioinformatics"},{"key":"7292_CR62","doi-asserted-by":"publisher","unstructured":"Gonzalez-Pena, V. et al. Accurate genomic variant detection in single cells with primary template-directed amplification. Proc. Natl Acad. Sci. USA https:\/\/doi.org\/10.1073\/pnas.2024176118 (2021).","DOI":"10.1073\/pnas.2024176118"},{"key":"7292_CR63","doi-asserted-by":"publisher","first-page":"W102","DOI":"10.1093\/nar\/gky406","volume":"46","author":"J Lee","year":"2018","unstructured":"Lee, J. et al. Mutalisk: a web-based somatic MUTation AnaLyIS toolKit for genomic, transcriptional and epigenomic signatures. Nucleic Acids Res. 46, W102\u2013W108 (2018).","journal-title":"Nucleic Acids Res."},{"key":"7292_CR64","doi-asserted-by":"publisher","first-page":"1792","DOI":"10.1093\/nar\/gkh340","volume":"32","author":"RC Edgar","year":"2004","unstructured":"Edgar, R. C. MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res. 32, 1792\u20131797 (2004).","journal-title":"Nucleic Acids Res."},{"key":"7292_CR65","doi-asserted-by":"publisher","first-page":"3022","DOI":"10.1093\/molbev\/msab120","volume":"38","author":"K Tamura","year":"2021","unstructured":"Tamura, K., Stecher, G. & Kumar, S. MEGA11: Molecular Evolutionary Genetics Analysis version 11. Mol. Biol. Evol. 38, 3022\u20133027 (2021).","journal-title":"Mol. Biol. Evol."}],"container-title":["Nature"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41586-024-07292-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41586-024-07292-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41586-024-07292-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T09:20:23Z","timestamp":1715160023000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41586-024-07292-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,10]]},"references-count":65,"journal-issue":{"issue":"8011","published-print":{"date-parts":[[2024,5,9]]}},"alternative-id":["7292"],"URL":"https:\/\/doi.org\/10.1038\/s41586-024-07292-5","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2023.10.24.563814","asserted-by":"object"}]},"ISSN":["0028-0836","1476-4687"],"issn-type":[{"value":"0028-0836","type":"print"},{"value":"1476-4687","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,10]]},"assertion":[{"value":"22 October 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"K.K. is a senior scientist at Bioskryb Genomics Inc. All other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}