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C.P.C. has financial interest in Axoft. L.N.G.C. receives consulting fees from Elsevier, Oakstone Publishing, Prime Education, BMJ Best Practice and Servier, and research funding from Merck & Co (to the Dana-Farber Cancer Institute). J.L.G. is consultant and serves on the scientific advisory board of Array BioPharma, AstraZeneca, BD Biosciences, Carisma, Codagenix, Duke Street Bio, GlaxoSmithKline, Kowa, Kymera, OncoOne and Verseau Therapeutics, and receives research support from Array BioPharma\/Pfizer, Eli Lilly, GlaxoSmithKline and Merck. M.L.S. is an equity holder, scientific co-founder and advisory board member of Immunitas Therapeutics. A.K.S. receives compensation for consulting and\/or scientific advisory board membership from Honeycomb Biotechnologies, Cellarity, Ochre Bio, Relation Therapeutics, FL86\/Quotient Therapeutics, Parabalis Medicines, Passkey Therapeutics, IntrECate Biotherapeutics, Danaher, Senda Biosciences and Dahlia Biosciences that is unrelated to this work. B.E.B. has financial interests in Fulcrum Therapeutics, HiFiBio, Arsenal Biosciences, Chroma Medicine and Cell Signaling Technologies. The other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}