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The Baker laboratory has received sponsored research funding from Novo Nordisk in support of the GLP1R, PAC1R, NK1R and PTH1R research described in this Article. A.B., L.D., N.L, M.B., J.S., K.D. and Y.W. were employees of Novo Nordisk at the time of the work, and some hold minor shareholdings as part of their employment. E.M., D.F., D.E.K., A.M.-B., P.R.-S., L.J.S., C.N., E.P.T.H., M.J, J.H.V., A.N., C.G.T., B.L.R. and D.B. are shareholders of Skape Bio. Skape Bio is seeking to commercialize aspects of the research described in this Article. B.L.R. is a member of the scientific advisory board of ImprintBio, XyloBio and Epiodyne. The other authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Ethics"}}]}}