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To provide a noninvasive alternative, we report nonsurgical implants consisting of immune cell\u2013electronics hybrids, an approach we call Circulatronics. The devices can be delivered intravenously and traffic autonomously to regions of inflammation in the brain, where they implant and enable neuromodulation, circumventing the need for surgery. To achieve suitable electronics, we designed and built subcellular-sized, wireless, photovoltaic electronic devices that harvest optical energy with high power conversion efficiency. In mice, we demonstrate nonsurgical implantation in an inflamed brain region, as an example of therapeutic target for several neural diseases, by employing monocytes as cells, covalently attaching them to the subcellular-sized, wireless, photovoltaic electronic devices and administering the resulting hybrids intravenously. We also demonstrate neural stimulation with 30-\u00b5m precision around the inflamed region. 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