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E.I. is now an employee of GlaxoSmithKline; all work was completed before his employment by GlaxoSmithKline. W.M. has received grants and\/or personal fees from the following companies\/corporations: Siemens Healthineers, Aegerion Pharmaceuticals, AMGEN, AstraZeneca, Sanofi, Alexion Pharmaceuticals, BASF, Abbott Diagnostics Numares, Berlin-Chemie, Akzea Therapeutics, Bayer Vital, Bestbion dx, Boehringer Ingelheim Pharma, Immundiagnostik, Merck Chemicals, MSD Sharp and Dohme, Novartis Pharma, Olink Proteomics and Synlab Holding Deutschland. M.I.M. has served on advisory panels for Pfizer, NovoNordisk and Zoe Global, and has received honoraria from Merck, Pfizer, NovoNordisk and Eli Lilly. He holds stock options in Zoe Global and has received research funding from Abbvie, Astra Zeneca, Boehringer Ingelheim, Eli Lilly, Janssen, Merck, NovoNordisk, Pfizer, Roche, Sanofi Aventis, Servier and Takeda. He is now an employee of Genentech and a holder of Roche stock. 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