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M.J. Borowitz. is on the advisory board for Amgen and Blueprint Medicines. I.I. has received honoraria from Amgen and Mission Bio. M.P. is an employee of Oxford Nanopore Technologies PLC. J.J.Y. has received research funding from Takeda Pharmaceuticals. The remaining authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}