{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T00:17:41Z","timestamp":1719015461514},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat Genet"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1038\/s41588-024-01780-0","type":"journal-article","created":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T10:02:01Z","timestamp":1717754521000},"page":"1053-1054","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["High-throughput fitness screens link genes to unique phenotypes in human-restricted Salmonella"],"prefix":"10.1038","volume":"56","member":"297","published-online":{"date-parts":[[2024,6,7]]},"reference":[{"key":"1780_CR1","doi-asserted-by":"crossref","unstructured":"Wang, B. X., Butler, D. S., Hamblin, M. & Monack, D. M. One species, different diseases: the unique molecular mechanisms that underlie the pathogenesis of typhoidal Salmonella infections. Curr. Opin. Microbiol. 72, 102262 (2023). A review article that presents a summary of genetic differences between non-typhoidal and typhoidal Salmonella.","DOI":"10.1016\/j.mib.2022.102262"},{"key":"1780_CR2","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1038\/ng1470","volume":"36","author":"M McClelland","year":"2004","unstructured":"McClelland, M. et al. Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat. Genet. 36, 1268\u20131274 (2004). This paper reports genomic comparisons between S. Typhiand S. Paratyphi A.","journal-title":"Nat. Genet."},{"key":"1780_CR3","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1038\/ng.195","volume":"40","author":"KE Holt","year":"2008","unstructured":"Holt, K. E. et al. High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi. Nat. Genet. 40, 987\u2013993 (2008). This paper uses bioinformatics to more deeply characterize the genomes of S. Typhi.","journal-title":"Nat. Genet."},{"key":"1780_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1128\/mBio.00306-15","volume":"6","author":"KM Wetmore","year":"2015","unstructured":"Wetmore, K. M. et al. Rapid quantification of mutant fitness in diverse bacteria by sequencing randomly bar-coded transposons. mBio 6, 1\u201315 (2015). This paper explains the principle and development of Rb-Tn-seq.","journal-title":"mBio"},{"key":"1780_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41467-022-30967-4","volume":"13","author":"D Leshchiner","year":"2022","unstructured":"Leshchiner, D. et al. A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance. Nat. Commun. 13, 1\u201317 (2022). This paper applies SAFE to systematically study the fitness of a Gram-positive pathogen.","journal-title":"Nat. Commun."}],"container-title":["Nature Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41588-024-01780-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41588-024-01780-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41588-024-01780-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T14:05:07Z","timestamp":1718978707000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41588-024-01780-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":5,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["1780"],"URL":"https:\/\/doi.org\/10.1038\/s41588-024-01780-0","relation":{},"ISSN":["1061-4036","1546-1718"],"issn-type":[{"value":"1061-4036","type":"print"},{"value":"1546-1718","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"7 June 2024","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 June 2024","order":2,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":3,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"In the version of the article initially published, \u201cCreated with Biorender.com\u201d was missing from the Fig. 1 legend and has now been added.","order":4,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}}]}}