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R.L.L. is on the supervisory board of Qiagen and was on the scientific advisory board of Loxo, Imago, Mana, Auron, C4 Therapeutics and Isoplexis, which include equity interest. R.L.L. receives research support from and consulted for Celgene and Roche and consults for Incyte, Lilly, Janssen, Astellas, Morphosys and Novartis. R.L.L. receives research support from Prelude and has received honoraria from AstraZeneca, Roche, Lilly and Amgen for invited lectures and from Gilead for grant reviews. O.E. is supported by Janssen and Eli Lilly research grants. O.E. is a scientific advisor and equity holder in Freenome, Owkin, Volastra Therapeutics and One Three Biotech. C.E.M. is a cofounder and board member for Biotia and Onegevity Health as well as an advisor or compensated speaker for Abbvie, Acuamark Diagnostics, ArcBio, Bio-Rad, DNA Genotek, Genialis, Genpro, Karius, Illumina, New England BioLabs, Qiagen, Whole Biome and Zymo Research. C.M. is a consultant and analyst for Onegevity Health. 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