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M.H.S. is founder and shareholder of Teiko.bio and Prox Biosciences, has received a speaking honorarium from Fluidigm, Arsenal and Kumquat, has been a paid consultant for Five Prime, Ono, January, Earli, Astellas and Indaptus, and has received research funding from Roche\/Genentech, Pfizer, Valitor and Bristol Myers Squibb. The other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}