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B.Z., K.M., D.A.S., Q.Y., L.Z., D.E.P., S.J.H., S.L., H.-O.B.N., G.Q., M.C.M., R.A., R.S. and E.J.R. are current employees and shareholders of Sangamo Therapeutics, Inc. S.F., D.L., J.R.P., J.C.M., I.A., D.G., L.K., J.M.C., Y.A., J.L., B.J.V., A.N., F.D.U., P.D.G. and H.S.Z. are former employees and shareholders of Sangamo Therapeutics, Inc. and were employed by Sangamo Therapeutics, Inc. when this work was conducted. S.K., J.B., L.M., L.P. and I.M.-S. are employed by CHDI Management, Inc. as advisors to CHDI Foundation, Inc., and declare no conflict of interest. CHDI Foundation, Inc. is a nonprofit biomedical research organization exclusively dedicated to developing therapeutics that substantially improve the lives of those affected by Huntington\u2019s disease, and conducts research in a number of different ways. 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