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J.D.W. is a consultant for: Adaptive Biotech; Amgen; Apricity; Ascentage Pharma; Arsenal IO; Astellas; AstraZeneca; Bayer; Beigene; Boehringer Ingelheim; Bristol Myers Squibb; Celgene; Chugai; Daiichi Sankyo; Dragonfly; Eli Lilly; Elucida; F Star; Georgiamune; Idera; Imvaq; Kyowa Hakko Kirin; Linneaus; Maverick Therapeutics; Merck; Neon Therapeutics; Polynoma; Psioxus; Recepta; Takara Bio; Trieza; Truvax; Trishula; Sellas; Serametrix; Surface Oncology; Syndax; Syntalogic; and Werewolf Therapeutics. J.D.W. receives research support grants from: Bristol Myers Squibb and Sephora. J.D.W. has equity in: Tizona Pharmaceuticals; Adaptive Biotechnologies; Imvaq; Beigene; Linneaus; Apricity; Arsenal IO; and Georgiamune. M.D.H. reports grants from BMS; personal fees from Achilles, Arcus, AstraZeneca, Blueprint, BMS, Eli Lilly, Genentech\/Roche, Genzyme\/Sanofi, Janssen, Immunai, Instil Bio, Mana Therapeutics, Merck, Mirati, Natera, Pact Pharma, Shattuck Labs and Regeneron; and equity options from Factorial, Immunai, Shattuck Labs and Arcus. A patent filed by Memorial Sloan Kettering related to the use of tumor mutational burden to predict response to immunotherapy (PCT\/US2015\/062208) is pending and licensed by PGDx. S.D. became employed at Regeneron Pharmaceuticals after his contributions to this work. All other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}