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Y.W., M.A., I.Y., A.Q., C.C., D.B., A.F., H.R.R., J.G., D.X., N.R., A.H., K.K., C.R., A.A., C.K.L., E.H., A.L., G.L., P.M.C.S., J.T. and M.G.F. are employees of NVIDIA and own stock as part of the standard compensation package. J.G. declares ownership of NVIDIA stock. I.D. is presently an officer and shareholder of Rhino HealthTech, Inc., which provides systems for distributed computation that can, among other things, be used to complete FL tasks. He was not employed by this company during the execution of the EXAM study. The remaining authors declare no competing interests. C.H. declares research travel with Siemens Healthineers AG; conference travel; and EUROKONGRESS and personal fees (consultant to GE Healthcare LLC, DSMB member, Focused Ultrasound Foundation). F.J.G. declares research collaboration with Merantix, Screen-Point, Lunit, Volpara and GE Healthcare, and undertakes paid consultancy for Kheiron and Alphabet. M.L. declares that he is the cofounder of PediaMetrix, Inc. and is on the board of the SIPAIM Foundation. S.E.H. declares research collaborations with Merantix, Screen-Point, Lunit and Volpara. B.J.W. and S.X. declare that NIH and NVIDIA have a Cooperative Research and Development Agreement. This work was supported (in part) by the NIH Center for Interventional Oncology and the Intramural Research Program of the National Institutes of Health, via intramural NIH grant nos. Z1ACL040015 and 1ZIDBC011242. Work was supported by the NIH Intramural Targeted Anti-COVID-19 Program, funded by the National Institute of Allergy and Infectious Diseases. NIH may have intellectual property in the field. M.F. is a consultant for Proof Diagnostics, a start-up company developing a CRISPR-based diagnostic test for COVID-19. 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