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H.R.K. and J.G. are named as inventors on PCT patent application 15\/878,640 entitled \u2018genotype-guided dosing of opioid agonists\u2019, filed on 24 January 2018. E.S. is a full-time employee of Regeneron Pharmaceuticals. The other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}