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K12 AR084222). The content of the article is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Z.I.A. is a co-inventor of several AI algorithms (including screening for low LVEF, QT tool, aortic stenosis and atrial fibrillation detection during normal sinus rhythm). These have been licensed to Anumana, AliveCor and Eko. The Mayo Clinic and Z.I.A. may benefit from their commercialization. Z.I.A. is a member of the scientific advisory board for Anumana, an AI company, receives stock options for being an inventor of the ejection fraction algorithm and is a consultant for Anumana, AliveCor and XAI.health. P.A.F. is a co-inventor of several AI algorithms (including screening for low LVEF, QT tool, aortic stenosis and atrial fibrillation detection during normal sinus rhythm). These have been licensed to Anumana, AliveCor and Eko. The Mayo Clinic and P.A.F. may benefit from their commercialization. P.A.F. is a member of the scientific advisory board for Anumana, an AI company. F.L.J. in conjunction with the Mayo Clinic has filed patents related to the application of AI to ECG for diagnosis and risk stratification. F.L.J. is a member of the scientific advisory board for Anumana, an AI company. P.A.N. and the Mayo Clinic have filed patents related to the application of AI to ECG for diagnosis and risk stratification and have licensed several AI-ECG algorithms to Anumana. P.A.N. and the Mayo Clinic are involved in potential equity\/royalty relationship with AliveCor. P.A.N. is a study investigator in an ablation trial sponsored by Medtronic. P.A.N. also has served on an expert advisory panel for OptumLabs. Y.B.T. has sponsored research grants from HeraMed, Mitre Corp (MSTORC development grant) and the COVID-19 Interactive Care Plan. Y.B.T. also receives know-how royalties for co-development of HeraBEAT from HeraMed Corp. R.E.C. is a scientific advisor for Anumana, an AI-driven health technology company commercializing ECG-based AI solutions. The other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}