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W.P. reports relationships with American Physician Institute for Advanced Professional Studies LLC, Astellas, EXACT Therapeutics AS, Integrity Continuing Education Inc. and Revolution Medicines and an uncompensated relationship with Break Through Cancer. U.A.S. reports institutional research funding from Celgene\/Bristol Myers Squibb and Janssen, institutional support from Sabinsa Pharmaceuticals and M&M Labs and personal fees from Janssen Biotech, Sanofi and i3Health, outside the submitted work. P.I. reports relationships with AstraZeneca and GE Healthcare and uncompensated relationships with AstraZeneca UK Limited and Incyte. M.D.G. holds equity in Faeth Therapeutics and Skye Biosciences; has consulting\/advisory roles with Almac Discovery, Faeth Therapeutics, Genentech, Scorpion Therapeutics, Skye Biosciences and Third Arc Bio; has received honoraria from Novartis, Pfizer and Genentech; and reports patents\/royalties\/intellectual property with Weill Cornell Medicine and Faeth Therapeutics. The remaining authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Ethics"}}]}}