{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:26:00Z","timestamp":1791260760133,"version":"4.1.0"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2018,2,5]],"date-time":"2018-02-05T00:00:00Z","timestamp":1517788800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nat Neurosci"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1038\/s41593-018-0074-8","type":"journal-article","created":{"date-parts":[[2018,1,31]],"date-time":"2018-01-31T20:50:08Z","timestamp":1517431808000},"page":"324-328","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Mrgprs on vagal sensory neurons contribute to bronchoconstriction and airway hyper-responsiveness"],"prefix":"10.1038","volume":"21","author":[{"given":"Liang","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9540-6171","authenticated-orcid":false,"given":"Nathachit","family":"Limjunyawong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Ru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia J.","family":"Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haley","family":"Steele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuyan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne","family":"Mitzner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marian","family":"Kollarik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley J.","family":"Undem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan J.","family":"Canning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9750-7718","authenticated-orcid":false,"given":"Xinzhong","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,2,5]]},"reference":[{"key":"74_CR1","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/B978-0-444-53491-0.00018-3","volume":"117","author":"SB Mazzone","year":"2013","unstructured":"Mazzone, S. B. & Canning, B. J. Handb. Clin. Neurol. 117, 215\u2013228 (2013).","journal-title":"Handb. Clin. Neurol."},{"key":"74_CR2","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/j.neuron.2015.06.007","volume":"87","author":"S Talbot","year":"2015","unstructured":"Talbot, S. et al. Neuron 87, 341\u2013354 (2015).","journal-title":"Neuron"},{"key":"74_CR3","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.resp.2015.03.007","volume":"212-214","author":"MA McAlexander","year":"2015","unstructured":"McAlexander, M. A., Gavett, S. H., Kollarik, M. & Undem, B. J. Respir. Physiol. Neurobiol. 212-214, 20\u201324 (2015).","journal-title":"Respir. Physiol. Neurobiol."},{"key":"74_CR4","doi-asserted-by":"publisher","first-page":"11515","DOI":"10.1073\/pnas.1411032111","volume":"111","author":"D Tr\u00e4nkner","year":"2014","unstructured":"Tr\u00e4nkner, D., Hahne, N., Sugino, K., Hoon, M. A. & Zuker, C. Proc. Natl Acad. Sci. USA 111, 11515\u201311520 (2014).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"74_CR5","doi-asserted-by":"publisher","first-page":"9099","DOI":"10.1073\/pnas.0900591106","volume":"106","author":"AI Caceres","year":"2009","unstructured":"Caceres, A. I. et al. Proc. Natl Acad. Sci. USA 106, 9099\u20139104 (2009).","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"74_CR6","doi-asserted-by":"publisher","first-page":"7563","DOI":"10.1523\/JNEUROSCI.1192-11.2011","volume":"31","author":"P Sikand","year":"2011","unstructured":"Sikand, P., Dong, X. & LaMotte, R. H. J. Neurosci. 31, 7563\u20137567 (2011).","journal-title":"J. Neurosci."},{"key":"74_CR7","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1016\/j.cell.2009.11.034","volume":"139","author":"Q Liu","year":"2009","unstructured":"Liu, Q. et al. Cell 139, 1353\u20131365 (2009).","journal-title":"Cell"},{"key":"74_CR8","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1002\/jez.b.21060","volume":"304","author":"CV Baker","year":"2005","unstructured":"Baker, C. V. & Schlosser, G. J. Exp. Zool. 304, 269\u2013273 (2005).","journal-title":"J. Exp. Zool."},{"key":"74_CR9","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1038\/nn.3289","volume":"16","author":"L Han","year":"2013","unstructured":"Han, L. et al. Nat. Neurosci. 16, 174\u2013182 (2013).","journal-title":"Nat. Neurosci."},{"key":"74_CR10","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1016\/j.neuron.2013.12.011","volume":"81","author":"YS Kim","year":"2014","unstructured":"Kim, Y. S. et al. Neuron 81, 873\u2013887 (2014).","journal-title":"Neuron"},{"key":"74_CR11","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1165\/rcmb.2008-0292OC","volume":"40","author":"TE Taylor-Clark","year":"2009","unstructured":"Taylor-Clark, T. E., Kiros, F., Carr, M. J. & McAlexander, M. A. Am. J. Respir. Cell. Mol. Biol. 40, 756\u2013762 (2009).","journal-title":"Am. J. Respir. Cell. Mol. Biol."},{"key":"74_CR12","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.1113\/jphysiol.2007.148379","volume":"586","author":"C Nassenstein","year":"2008","unstructured":"Nassenstein, C. et al. J. Physiol. (Lond.) 586, 1595\u20131604 (2008).","journal-title":"J. Physiol. (Lond.)"},{"key":"74_CR13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0117128","volume":"10","author":"MA Ha","year":"2015","unstructured":"Ha, M. A. et al. PLoS. One 10, e0117128 (2015).","journal-title":"PLoS. One"},{"key":"74_CR14","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1016\/j.jaci.2006.04.052","volume":"118","author":"C Nassenstein","year":"2006","unstructured":"Nassenstein, C. et al. J. Allergy Clin. Immunol. 118, 597\u2013605 (2006).","journal-title":"J. Allergy Clin. Immunol."},{"key":"74_CR15","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1152\/japplphysiol.00313.2006","volume":"101","author":"BJ Canning","year":"2006","unstructured":"Canning, B. J. J. Appl. Physiol. 101, 971\u2013985 (2006).","journal-title":"J. Appl. Physiol."},{"key":"74_CR16","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1111\/j.1365-2125.2011.03913.x","volume":"71","author":"L Nel","year":"2011","unstructured":"Nel, L. & Eren, E. Br. J. Clin. Pharmacol. 71, 647\u2013658 (2011).","journal-title":"Br. J. Clin. Pharmacol."},{"key":"74_CR17","doi-asserted-by":"publisher","first-page":"1521","DOI":"10.1016\/j.jaci.2013.11.027","volume":"133","author":"BJ Undem","year":"2014","unstructured":"Undem, B. J. & Taylor-Clark, T. J. Allergy Clin. Immunol. 133, 1521\u20131534 (2014).","journal-title":"Allergy Clin. Immunol."},{"key":"74_CR18","doi-asserted-by":"publisher","first-page":"2251","DOI":"10.4049\/jimmunol.180.4.2251","volume":"180","author":"MG Lee","year":"2008","unstructured":"Lee, M. G. et al. J. Immunol. 180, 2251\u20132255 (2008).","journal-title":"J. Immunol."},{"key":"74_CR19","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1038\/ni.3049","volume":"16","author":"BN Lambrecht","year":"2015","unstructured":"Lambrecht, B. N. & Hammad, H. Nat. Immunol. 16, 45\u201356 (2015).","journal-title":"Nat. Immunol."},{"key":"74_CR20","doi-asserted-by":"publisher","first-page":"S213","DOI":"10.1067\/mai.2000.110153","volume":"106","author":"BJ Undem","year":"2000","unstructured":"Undem, B. J., Kajekar, R., Hunter, D. D. & Myers, A. C. J. Allergy Clin. Immunol. 106 Suppl, S213\u2013S220 (2000).","journal-title":"J. Allergy Clin. Immunol."},{"key":"74_CR21","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1113\/jphysiol.2007.146365","volume":"586","author":"K Kwong","year":"2008","unstructured":"Kwong, K. et al. J. Physiol. (Lond.) 586, 1321\u20131336 (2008).","journal-title":"J. Physiol. (Lond.)"},{"key":"74_CR22","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1113\/jphysiol.2003.060079","volume":"556","author":"BJ Undem","year":"2004","unstructured":"Undem, B. J. et al. J. Physiol. (Lond.) 556, 905\u2013917 (2004).","journal-title":"J. Physiol. (Lond.)"},{"key":"74_CR23","doi-asserted-by":"publisher","first-page":"3355","DOI":"10.1113\/jphysiol.2009.173054","volume":"587","author":"LA Weigand","year":"2009","unstructured":"Weigand, L. A., Myers, A. C., Meeker, S. & Undem, B. J. J. Physiol. (Lond.) 587, 3355\u20133362 (2009).","journal-title":"J. Physiol. (Lond.)"}],"container-title":["Nature Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/s41593-018-0074-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41593-018-0074-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/s41593-018-0074-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T22:15:50Z","timestamp":1684620950000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41593-018-0074-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,5]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["74"],"URL":"https:\/\/doi.org\/10.1038\/s41593-018-0074-8","relation":{},"ISSN":["1097-6256","1546-1726"],"issn-type":[{"value":"1097-6256","type":"print"},{"value":"1546-1726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,5]]},"assertion":[{"value":"23 August 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2017","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 February 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing financial interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}