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These, in turn, control many aspects of an animal\u2019s physiology and development, including growth, reproduction, homeostasis, metabolism, and stress responses. In teleost fish, each hormone is presumably produced by a specific cell type. However, key details on the regulation of, and communication between these cell types remain to be resolved. We have therefore used single-cell sequencing to generate gene expression profiles for 2592 and 3804 individual cells from the pituitaries of female and male adult medaka (\n                    <jats:italic>Oryzias latipes<\/jats:italic>\n                    ), respectively. Based on expression profile clustering, we define 15 and 16 distinct cell types in the female and male pituitary, respectively, of which ten are involved in the production of a single peptide hormone. Collectively, our data provide a high-quality reference for studies on pituitary biology and the regulation of hormone production, both in fish and in vertebrates in general.\n                  <\/jats:p>","DOI":"10.1038\/s41597-021-01058-8","type":"journal-article","created":{"date-parts":[[2021,10,28]],"date-time":"2021-10-28T06:02:44Z","timestamp":1635400964000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Characterization of hormone-producing cell types in the teleost pituitary gland using single-cell RNA-seq"],"prefix":"10.1038","volume":"8","author":[{"given":"Khadeeja","family":"Siddique","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eirill","family":"Ager-Wick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1123-9773","authenticated-orcid":false,"given":"Romain","family":"Fontaine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5111-1558","authenticated-orcid":false,"given":"Finn-Arne","family":"Weltzien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9838-8215","authenticated-orcid":false,"given":"Christiaan V.","family":"Henkel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,10,28]]},"reference":[{"key":"1058_CR1","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1210\/er.2009-0008","volume":"30","author":"D Kelberman","year":"2009","unstructured":"Kelberman, D., Rizzoti, K., Lovell-Badge, R., Robinson, I. 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