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Since 1948, when Sophie Spitz first described them, the diagnostic uncertainty remains until now, especially in the intermediate category known as Spitz tumor of unknown malignant potential (STUMP) or atypical Spitz tumor. Studies developing deep learning (DL) models to diagnose melanocytic tumors using whole slide imaging (WSI) are scarce, and few used ST for analysis, excluding STUMP. To address this gap, we introduce SOPHIE: the first ST dataset with WSIs, including labels as benign, malignant, and atypical tumors, along with the clinical information of each patient. Additionally, we explain two DL models implemented as validation examples using this database.<\/jats:p>","DOI":"10.1038\/s41597-023-02585-2","type":"journal-article","created":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T04:02:37Z","timestamp":1697428957000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["A Spitzoid Tumor dataset with clinical metadata and Whole Slide Images for Deep Learning models"],"prefix":"10.1038","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6158-9619","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Mosquera-Zamudio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"La\u00ebtitia","family":"Launet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roc\u00edo","family":"del Amor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana\u00efs","family":"Moscard\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adri\u00e1n","family":"Colomer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valery","family":"Naranjo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Monteagudo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,10,16]]},"reference":[{"key":"2585_CR1","first-page":"591","volume":"24","author":"S Spitz","year":"1948","unstructured":"Spitz, S. Melanomas of childhood. The American journal of pathology 24, 591 (1948).","journal-title":"The American journal of pathology"},{"key":"2585_CR2","unstructured":"Elder, D. E., Massi, D., Scolyer, R. A. & Willemze, R.WHO classification of skin tumours (International Agency for Research on Cancer, 2018)."},{"key":"2585_CR3","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.5858\/arpa.2015-0207-RA","volume":"139","author":"KL Harms","year":"2015","unstructured":"Harms, K. L., Lowe, L., Fullen, D. R. & Harms, P. W. Atypical spitz tumors: a diagnostic challenge. Archives of pathology & laboratory medicine 139, 1263\u20131270 (2015).","journal-title":"Archives of pathology & laboratory medicine"},{"key":"2585_CR4","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1111\/j.1440-0960.1997.tb01091.x","volume":"38","author":"DC Orchard","year":"1997","unstructured":"Orchard, D. C., Dowling, J. P. & Kelly, J. W. 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