{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T01:26:01Z","timestamp":1792373161432,"version":"4.4.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T00:00:00Z","timestamp":1713744000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T00:00:00Z","timestamp":1713744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Data"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cocaine use disorder (CUD) is a global health problem with severe consequences, leading to behavioral, cognitive, and neurobiological disturbances. While consensus on treatments is still ongoing, repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising approach for medication-resistant disorders, including substance use disorders. In this context, here we present the SUDMEX-TMS, a Mexican dataset from an rTMS clinical trial involving CUD patients. This longitudinal dataset comprises 54 CUD patients (including 8 females) with data collected at five time points: baseline (T0), two weeks (T1), three months (T2), six months (T3) follow-up, and twelve months (T4) follow-up. The clinical rTMS treatment followed a double-blinded randomized clinical trial design (n\u2009=\u200924 sham\/30 active) for 2 weeks, followed by an open-label phase. The dataset includes demographic, clinical, and cognitive measures, as well as magnetic resonance imaging (MRI) data collected at all time points, encompassing structural (T1-weighted), functional (resting-state fMRI), and multishell diffusion-weighted (DWI-HARDI) sequences. This dataset offers the opportunity to investigate the impact of rTMS on CUD participants, considering clinical, cognitive, and multimodal MRI metrics in a longitudinal framework.<\/jats:p>","DOI":"10.1038\/s41597-024-03242-y","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T03:01:49Z","timestamp":1713754909000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The Mexican dataset of a repetitive transcranial magnetic stimulation clinical trial on cocaine use disorder patients: SUDMEX TMS"],"prefix":"10.1038","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8029-8369","authenticated-orcid":false,"given":"Diego","family":"Angeles-Valdez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5216-7177","authenticated-orcid":false,"given":"Jalil","family":"Rasgado-Toledo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviana","family":"Villica\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Davalos-Guzman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Almanza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Fajardo-Valdez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Alcala-Lozano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1381-8648","authenticated-orcid":false,"given":"Eduardo A.","family":"Garza-Villarreal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,22]]},"reference":[{"key":"3242_CR1","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1111\/add.14234","volume":"113","author":"A Peacock","year":"2018","unstructured":"Peacock, A. et al. Global statistics on alcohol, tobacco and illicit drug use: 2017 status report. Addiction 113, 1905\u20131926 (2018).","journal-title":"Addiction"},{"key":"3242_CR2","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1097\/ADM.0000000000000066","volume":"8","author":"S Potvin","year":"2014","unstructured":"Potvin, S., Stavro, K., Rizkallah, E. & Pelletier, J. Cocaine and cognition: a systematic quantitative review. J. Addict. Med. 8, 368\u2013376 (2014).","journal-title":"J. Addict. Med."},{"key":"3242_CR3","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.1111\/j.1465-7295.2012.00506.x","volume":"51","author":"RG Fryer Jr","year":"2013","unstructured":"Fryer, R. G. Jr, Heaton, P. S., Levitt, S. D. & Murphy, K. M. Measuring crack cocaine and its impact. Econ. Inq. 51, 1651\u20131681 (2013).","journal-title":"Econ. Inq."},{"key":"3242_CR4","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aax1532","volume":"5","author":"KM Kampman","year":"2019","unstructured":"Kampman, K. M. The treatment of cocaine use disorder. Sci Adv 5, eaax1532 (2019).","journal-title":"Sci Adv"},{"key":"3242_CR5","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.euroneuro.2015.11.011","volume":"26","author":"A Terraneo","year":"2016","unstructured":"Terraneo, A. et al. Transcranial magnetic stimulation of dorsolateral prefrontal cortex reduces cocaine use: A pilot study. Eur. Neuropsychopharmacol. 26, 37\u201344 (2016).","journal-title":"Eur. Neuropsychopharmacol."},{"key":"3242_CR6","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1080\/10550490802139283","volume":"17","author":"E Politi","year":"2008","unstructured":"Politi, E., Fauci, E., Santoro, A. & Smeraldi, E. Daily sessions of transcranial magnetic stimulation to the left prefrontal cortex gradually reduce cocaine craving. Am. J. Addict. 17, 345\u2013346 (2008).","journal-title":"Am. J. Addict."},{"key":"3242_CR7","doi-asserted-by":"crossref","unstructured":"Protasio, M. I. B. et al. The Effects of Repetitive Transcranial Magnetic Stimulation in Reducing Cocaine Craving and Use. Addictive Disorders & Their Treatment 18, 212\u2013222 (2019).","DOI":"10.1097\/ADT.0000000000000169"},{"key":"3242_CR8","doi-asserted-by":"publisher","first-page":"173240","DOI":"10.1016\/j.pbb.2021.173240","volume":"209","author":"VR Steele","year":"2021","unstructured":"Steele, V. R. & Maxwell, A. M. Treating cocaine and opioid use disorder with transcranial magnetic stimulation: A path forward. Pharmacol. Biochem. Behav. 209, 173240 (2021).","journal-title":"Pharmacol. Biochem. Behav."},{"key":"3242_CR9","doi-asserted-by":"crossref","unstructured":"Moretti, J., Poh, E. Z. & Rodger, J. rTMS-Induced Changes in Glutamatergic and Dopaminergic Systems: Relevance to Cocaine and Methamphetamine Use Disorders. Frontiers in Neuroscience.14, 137 (2020).","DOI":"10.3389\/fnins.2020.00137"},{"key":"3242_CR10","doi-asserted-by":"crossref","unstructured":"Garza-Villarreal, E. A. et al. Clinical and Functional Connectivity Outcomes of 5-Hz Repetitive Transcranial Magnetic Stimulation as an Add-on Treatment in Cocaine Use Disorder: A Double-Blind Randomized Controlled Trial. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 6, 745\u2013757 (2021).","DOI":"10.1016\/j.bpsc.2021.01.003"},{"key":"3242_CR11","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2019.109709","volume":"95","author":"S Jim\u00e9nez","year":"2019","unstructured":"Jim\u00e9nez, S. et al. Identifying cognitive deficits in cocaine dependence using standard tests and machine learning. Prog. Neuropsychopharmacol. Biol. Psychiatry 95, 109709 (2019).","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"3242_CR12","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2021.117934","volume":"233","author":"F Zhang","year":"2021","unstructured":"Zhang, F. et al. Deep learning based segmentation of brain tissue from diffusion MRI. Neuroimage 233, 117934 (2021).","journal-title":"Neuroimage"},{"key":"3242_CR13","doi-asserted-by":"crossref","unstructured":"Rasgado-Toledo, J., Issa-Garcia, V., Alcal\u00e1-Lozano, R., Garza-Villarreal, E. A. & Gonz\u00e1lez-Escamilla, G. Cortical and subcortical microstructure integrity changes after repetitive transcranial magnetic stimulation therapy in cocaine use disorder and relates to clinical outcomes. Addict. Biol. 29, e13381 (2024).","DOI":"10.1111\/adb.13381"},{"key":"3242_CR14","doi-asserted-by":"publisher","unstructured":"Zhao, K. et al. A generalizable functional connectivity signature characterizes brain dysfunction and links to rTMS treatment response in cocaine use disorder. medRxiv, https:\/\/doi.org\/10.1101\/2023.04.21.23288948 (2023).","DOI":"10.1101\/2023.04.21.23288948"},{"key":"3242_CR15","doi-asserted-by":"publisher","DOI":"10.1038\/s41597-022-01251-3","volume":"9","author":"D Angeles-Valdez","year":"2022","unstructured":"Angeles-Valdez, D. et al. The Mexican magnetic resonance imaging dataset of patients with cocaine use disorder: SUDMEX CONN. Sci Data 9, 133 (2022).","journal-title":"Sci Data"},{"key":"3242_CR16","unstructured":"Ferrando, L., Bobes, J., Gibert, M., Soto, M. & Soto, O. M.I.N.I. Mini International Neuropsychiatric Interview. Versi\u00f3n en espa\u00f1ol 5.0.0.DSM-IV. Instituto IAP, Madrid, (1998)."},{"key":"3242_CR17","doi-asserted-by":"publisher","DOI":"10.5281\/zenodo.3524401","author":"OF Gulban","year":"2019","unstructured":"Gulban, O. F. et al. poldracklab\/pydeface: v2. 0.0. Zenodo https:\/\/doi.org\/10.5281\/zenodo.3524401 (2019)."},{"key":"3242_CR18","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/0013-4694(94)90029-9","volume":"91","author":"PM Rossini","year":"1994","unstructured":"Rossini, P. M. et al. Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application. Report of an IFCN committee. Electroencephalogr. Clin. Neurophysiol. 91, 79\u201392 (1994).","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"3242_CR19","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/j.brs.2020.01.010","volume":"13","author":"NT Trapp","year":"2020","unstructured":"Trapp, N. T. et al. Reliability of targeting methods in TMS for depression: Beam F3 vs. 5.5 cm. Brain Stimul. 13, 578\u2013581 (2020).","journal-title":"Brain Stimul."},{"key":"3242_CR20","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1111\/j.2044-8341.1959.tb00467.x","volume":"32","author":"M Hamilton","year":"1959","unstructured":"Hamilton, M. The assessment of anxiety states by rating. Br. J. Med. Psychol. 32, 50\u201355 (1959).","journal-title":"Br. J. Med. Psychol."},{"key":"3242_CR21","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","volume":"28","author":"DJ Buysse","year":"1989","unstructured":"Buysse, D. J. et al. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 28, 193\u2013213 (1989).","journal-title":"Psychiatry Res."},{"key":"3242_CR22","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.1365-2125.1978.tb01673.x","volume":"6","author":"AN Nicholson","year":"1978","unstructured":"Nicholson, A. N. Visual analogue scales and drug effects in man. Br. J. Clin. Pharmacol. 6, 3\u20134 (1978).","journal-title":"Br. J. Clin. Pharmacol."},{"key":"3242_CR23","first-page":"335","volume":"14","author":"JA Ramos-Brieva","year":"1986","unstructured":"Ramos-Brieva, J. A. & Cordero Villaf\u00e1fila, A. [Relation between the validity and reliability of the Castillian version of the Hamilton Rating Scale for Depression]. Actas Luso. Esp. Neurol. Psiquiatr. Cienc. Afines 14, 335\u2013338 (1986).","journal-title":"Actas Luso. Esp. Neurol. Psiquiatr. Cienc. Afines"},{"key":"3242_CR24","doi-asserted-by":"crossref","unstructured":"The Psychology Experiment Building Language (PEBL) and PEBL Test Battery. J. Neurosci. Methods 222, 250\u2013259 (2014).","DOI":"10.1016\/j.jneumeth.2013.10.024"},{"key":"3242_CR25","doi-asserted-by":"publisher","DOI":"10.1038\/sdata.2016.44","volume":"3","author":"KJ Gorgolewski","year":"2016","unstructured":"Gorgolewski, K. J. et al. The brain imaging data structure, a format for organizing and describing outputs of neuroimaging experiments. Sci Data 3, 160044 (2016).","journal-title":"Sci Data"},{"key":"3242_CR26","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.jneumeth.2016.03.001","volume":"264","author":"X Li","year":"2016","unstructured":"Li, X., Morgan, P. S., Ashburner, J., Smith, J. & Rorden, C. The first step for neuroimaging data analysis: DICOM to NIfTI conversion. J. Neurosci. Methods 264, 47\u201356 (2016).","journal-title":"J. Neurosci. Methods"},{"key":"3242_CR27","doi-asserted-by":"crossref","unstructured":"Markiewicz, C. J. et al. The OpenNeuro resource for sharing of neuroscience data. Elife 10, (2021).","DOI":"10.7554\/eLife.71774"},{"key":"3242_CR28","doi-asserted-by":"publisher","DOI":"10.18112\/openneuro.ds003037.v2.1.0","author":"D Angeles-Valdez","year":"2023","unstructured":"Angeles-Valdez, D. et al. SUDMEX_TMS. OpenNeuro https:\/\/doi.org\/10.18112\/openneuro.ds003037.v2.1.0 (2023)."},{"key":"3242_CR29","doi-asserted-by":"publisher","DOI":"10.5281\/zenodo.10409461","author":"D Angeles-Valdez","year":"2023","unstructured":"Angeles-Valdez, D. et al. The Mexican dataset of an rTMS clinical trial on cocaine use disorder patients: SUDMEX TMS (V4.2). Zenodo. https:\/\/doi.org\/10.5281\/zenodo.10409461 (2023)."},{"key":"3242_CR30","doi-asserted-by":"publisher","first-page":"e0184661","DOI":"10.1371\/journal.pone.0184661","volume":"12","author":"O Esteban","year":"2017","unstructured":"Esteban, O. et al. MRIQC: Advancing the automatic prediction of image quality in MRI from unseen sites. PLoS One 12, e0184661 (2017).","journal-title":"PLoS One"},{"key":"3242_CR31","doi-asserted-by":"crossref","unstructured":"McRobbie, D. W., Moore, E. A., Graves, M. J. & Prince, M. R. MRI from Picture to Proton. (Cambridge University Press, 2017).","DOI":"10.1017\/9781107706958"},{"key":"3242_CR32","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1007\/s10278-006-0264-x","volume":"19","author":"VA Magnotta","year":"2006","unstructured":"Magnotta, V. A., Friedman, L. & Birn, First Measurement of Signal-to-Noise and Contrast-to-Noise in the fBIRN Multicenter Imaging Study. J. Digit. Imaging 19, 140\u2013147 (2006).","journal-title":"J. Digit. Imaging"},{"key":"3242_CR33","doi-asserted-by":"publisher","first-page":"2142","DOI":"10.1016\/j.neuroimage.2011.10.018","volume":"59","author":"JD Power","year":"2012","unstructured":"Power, J. D., Barnes, K. A., Snyder, A. Z., Schlaggar, B. L. & Petersen, S. E. Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage 59, 2142\u20132154 (2012).","journal-title":"Neuroimage"},{"key":"3242_CR34","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1016\/j.neuroimage.2006.09.032","volume":"34","author":"K Murphy","year":"2007","unstructured":"Murphy, K., Bodurka, J. & Bandettini, P. A. How long to scan? The relationship between fMRI temporal signal to noise ratio and necessary scan duration. Neuroimage 34, 565\u2013574 (2007).","journal-title":"Neuroimage"},{"key":"3242_CR35","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1016\/j.neuroimage.2018.09.073","volume":"184","author":"M Bastiani","year":"2019","unstructured":"Bastiani, M. et al. Automated quality control for within and between studies diffusion MRI data using a non-parametric framework for movement and distortion correction. Neuroimage 184, 801\u2013812 (2019).","journal-title":"Neuroimage"},{"key":"3242_CR36","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1016\/j.neuroimage.2015.10.019","volume":"125","author":"JLR Andersson","year":"2016","unstructured":"Andersson, J. L. R. & Sotiropoulos, S. N. An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging. Neuroimage 125, 1063\u20131078 (2016).","journal-title":"Neuroimage"},{"key":"3242_CR37","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.neuroimage.2017.11.024","volume":"167","author":"J-P Fortin","year":"2018","unstructured":"Fortin, J.-P. et al. Harmonization of cortical thickness measurements across scanners and sites. Neuroimage 167, 104\u2013120 (2018).","journal-title":"Neuroimage"}],"container-title":["Scientific Data"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41597-024-03242-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41597-024-03242-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41597-024-03242-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T03:03:13Z","timestamp":1713754993000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41597-024-03242-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,22]]},"references-count":37,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["3242"],"URL":"https:\/\/doi.org\/10.1038\/s41597-024-03242-y","relation":{"references":[{"id-type":"doi","id":"10.5281\/zenodo.3524401","asserted-by":"subject"},{"id-type":"doi","id":"10.18112\/openneuro.ds003037.v2.1.0","asserted-by":"subject"},{"id-type":"doi","id":"10.5281\/zenodo.10409461","asserted-by":"subject"}],"has-preprint":[{"id-type":"doi","id":"10.1101\/2023.06.21.23291661","asserted-by":"object"}]},"ISSN":["2052-4463"],"issn-type":[{"value":"2052-4463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,22]]},"assertion":[{"value":"31 July 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"408"}}