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Since the establishment of the Expanded Special Project for Elimination of Neglected Tropical Diseases (ESPEN) in 2016, data on mass drug administration (MDA) with ivermectin has been centrally compiled for all endemic countries at implementation unit (IU) level, beginning in 2013. This paper presents HISTONCHO, a dataset collating detailed information on interventions, including vector control, from 1975 through to 2022, using the ESPEN portal (2013\u20132022), regional and country reports, implementation partners\u2019 records, and published literature. Reconstructing such intervention histories is crucial for an understanding of their evolution, modelling their impact, and tailoring future interventions. We discuss strengths and limitations associated with the ESPEN database, and how HISTONCHO can be improved to support modelling of intervention strategies as well as onchocerciasis control and elimination efforts by endemic country programmes.<\/jats:p>","DOI":"10.1038\/s41597-026-06852-w","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:35:47Z","timestamp":1771475747000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["HISTONCHO: A dataset of intervention histories for onchocerciasis control &amp; elimination in sub-Saharan Africa"],"prefix":"10.1038","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1710-6237","authenticated-orcid":false,"given":"Matthew A.","family":"Dixon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8714-5365","authenticated-orcid":false,"given":"Martin","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2120-4629","authenticated-orcid":false,"given":"Aditya","family":"Ramani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenna E.","family":"Coalson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Griswold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory S.","family":"Noland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Tate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emeka","family":"Makata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed M. 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