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Delineations were performed by delineators with varying levels of experience, including radiologists, radiology and urology residents, and medical students, which enables both inter-reader variability analysis and stratification by reader experience. Across all 467 cases in the LUND-PROBE dataset, at least one paired segmentation of the prostate and intraprostatic urethra was created for each case, yielding 1,227 paired segmentations in total. 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Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74, 229\u2013263, https:\/\/doi.org\/10.3322\/caac.21834 (2024).","journal-title":"CA Cancer J Clin"},{"key":"7738_CR2","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1200\/JCO.20.02873","volume":"39","author":"LGW Kerkmeijer","year":"2021","unstructured":"Kerkmeijer, L. G. W. et al. Focal Boost to the Intraprostatic Tumor in External Beam Radiotherapy for Patients With Localized Prostate Cancer: Results From the FLAME Randomized Phase III Trial. J Clin Oncol 39, 787\u2013796, https:\/\/doi.org\/10.1200\/JCO.20.02873 (2021).","journal-title":"J Clin Oncol"},{"key":"7738_CR3","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.ijrobp.2021.06.037","volume":"112","author":"JE Leeman","year":"2022","unstructured":"Leeman, J. E. et al. 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