{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:06:25Z","timestamp":1790741185954,"version":"4.1.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["2022.03176.PTDC"],"award-info":[{"award-number":["2022.03176.PTDC"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Data"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Babesia ovis<\/jats:italic>\n                    is a unicellular parasite of sheep and goats transmitted by the tick\n                    <jats:italic>Rhipicephalus bursa<\/jats:italic>\n                    .\n                    <jats:italic>B. ovis<\/jats:italic>\n                    infection is widespread and can be lethal, and therefore there is need for a deeper understanding of its biology and pathogenesis. There is currently a single genome available for a clinical isolate of\n                    <jats:italic>B. ovis<\/jats:italic>\n                    , and no laboratory strains have been sequenced so far. In this study we have sequenced and assembled the genome of the Israeli laboratory strain of\n                    <jats:italic>B. ovis<\/jats:italic>\n                    using highly accurate long-read sequencing (PacBio HiFi). The resulting assembly has high contiguity, with the four largest contigs comprising 96% of the assembly and representing putative near-complete chromosomes. Annotation identified 3,549 genes, of which 3,046 (85.6%) could be functionally annotated. BUSCO analysis on the annotated genes revealed 95.5%, 98.8% and 100% completeness of the Aconoidasida, Apicomplexa, and Alveolata lineages, respectively. Comparative analysis with other annotated piroplasmida genomes reveals the vast majority of predicted genes clustered in orthogroups. The availability of a high-quality genome assembly for a tractable laboratory strain could prove impactful in unlocking more basic and applied research avenues to be pursued for this important parasite system.\n                  <\/jats:p>","DOI":"10.1038\/s41597-026-08397-4","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:34:36Z","timestamp":1790739276000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Genome assembly and gene annotation of Babesia ovis Israeli strain (Piroplasmida: Babesiidae) using PacBio HiFi sequencing"],"prefix":"10.1038","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1459-3148","authenticated-orcid":false,"given":"Guilherme","family":"Borges Dias","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisele","family":"Albuquerque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannes","family":"Yngve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5357-0136","authenticated-orcid":false,"given":"Monica L.","family":"Mazuz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Domingos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Antunes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"8397_CR1","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/S0304-4017(97)00143-X","volume":"74","author":"I Yeruham","year":"1998","unstructured":"Yeruham, I., Hadani, A. & Galker, F. Some epizootiological and clinical aspects of ovine babesiosis caused by Babesia ovis\u2014a review. Veterinary Parasitology 74, 153\u2013163 (1998).","journal-title":"Veterinary Parasitology"},{"key":"8397_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11250-025-04450-3","volume":"57","author":"B Esmaeilnejad","year":"2025","unstructured":"Esmaeilnejad, B. et al. A review of Babesiosis caused by Babesia ovis in small ruminants. Tropical Animal Health and Production 57, 1\u201320 (2025).","journal-title":"Tropical Animal Health and Production"},{"key":"8397_CR3","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.pt.2025.02.008","volume":"41","author":"DF Li","year":"2025","unstructured":"Li, D. F. et al. Pushing the frontiers of babesiosis research: in vitro culture and gene editing. 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