{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T12:51:07Z","timestamp":1790427067671,"version":"4.1.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T00:00:00Z","timestamp":1496102400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T00:00:00Z","timestamp":1496102400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The hemibiotrophic fungus <jats:italic>Colletotrichum graminicola<\/jats:italic> may cause severe damage to maize, affecting normal development of the plant and decreasing grain yield. In this context, understanding plant defense pathways at the inoculation site and systemically in uninoculated tissues can help in the development of genetic engineering of resistance against this pathogen. Previous work has discussed the molecular basis of maize - <jats:italic>C. graminicola<\/jats:italic> interaction. However, many genes involved in defense have not yet been exploited for lack of annotation in public databases. Here, changes in global gene expression were studied in root, male and female inflorescences of maize under local and systemic fungal infection treatments, respectively. RNA-Seq with qPCR was used to indicate genes involved in plant defense. We found that systemic acquired resistance induction in female inflorescences mainly involves accumulation of salicylic acid (SA)-inducible defense genes (<jats:italic>ZmNAC<\/jats:italic>, <jats:italic>ZmHSF<\/jats:italic>, <jats:italic>ZmWRKY<\/jats:italic>, <jats:italic>ZmbZIP<\/jats:italic> and <jats:italic>PR1<\/jats:italic>) and potential genes involved in chromatin modification. Furthermore, transcripts involved in jasmonic acid (JA) and ethylene (ET) signaling pathways were also accumulated and may participate in plant immunity. Moreover, several genes were functionally re-annotated based on domain signature, indicating novel candidates to be tested in strategies involving gene knockout and overexpression in plants.<\/jats:p>","DOI":"10.1038\/s41598-017-02298-8","type":"journal-article","created":{"date-parts":[[2017,5,23]],"date-time":"2017-05-23T09:49:28Z","timestamp":1495532968000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Comparative transcriptomic analysis indicates genes associated with local and systemic resistance to Colletotrichum graminicola in maize"],"prefix":"10.1038","volume":"7","author":[{"given":"V\u00edvian de Jesus","family":"Miranda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4739-8250","authenticated-orcid":false,"given":"William Farias","family":"Porto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4897-8521","authenticated-orcid":false,"given":"Gabriel da Rocha","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Pogue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego Oliveira","family":"Nolasco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Claudia Guerra","family":"Araujo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano Viana","family":"Cota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila Guimar\u00e3es de","family":"Freitas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simoni Campos","family":"Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Octavio Luiz","family":"Franco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,5,30]]},"reference":[{"key":"2298_CR1","doi-asserted-by":"crossref","unstructured":"Frey, T. 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Nature genetics \n                           44, 1060\u20131065 (2012).","journal-title":"Nature genetics"},{"key":"2298_CR6","doi-asserted-by":"publisher","first-page":"1342","DOI":"10.1104\/pp.111.190397","volume":"158","author":"WA Vargas","year":"2012","unstructured":"Vargas, W. A. et al. Plant defense mechanisms are activated during biotrophic and necrotrophic development of Colletotricum graminicola in maize. Plant physiology \n                           158, 1342\u20131358 (2012).","journal-title":"Plant physiology"},{"key":"2298_CR7","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1016\/j.plaphy.2008.06.011","volume":"46","author":"J Sels","year":"2008","unstructured":"Sels, J., Mathys, J., De Coninck, B. M., Cammue, B. P. & De Bolle, M. F. Plant pathogenesis-related (PR) proteins: a focus on PR peptides. 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