{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T01:03:11Z","timestamp":1776128591140,"version":"3.50.1"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,5,24]],"date-time":"2017-05-24T00:00:00Z","timestamp":1495584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2017,5,24]],"date-time":"2017-05-24T00:00:00Z","timestamp":1495584000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Degeneration of the substantia innominata (SI) is significantly correlated with cognitive performance in Parkinson\u2019s disease (PD). We examined functional and structural patterns of SI degeneration in drug-na\u00efve PD patients according to the duration of parkinsonism before mild cognitive impairment (MCI) diagnosis. Twenty PD patients with a shorter duration (PD-MCI-SD, &lt;1 year), 18 patients with a longer duration (PD-MCI-LD, \u22651 year), and 29 patients with intact cognition (PD-IC) were included. Seed-based resting-state functional connectivity (rsFC) analysis using bilateral SI seed and region-of-interest-based volumetric analysis were performed. Compared to PD-IC, the collapsed PD-MCI group showed altered rsFC in the right frontal and bilateral parietal areas. PD-MCI-SD showed rsFC alteration in broader frontal and parietal areas compared to the other groups. Decreased rsFC in the right frontal area was also significantly correlated with shorter disease duration. No significant SI volume change was found between the groups. Altered rsFC between the SI and the frontal and parietal areas might be relevant to cognitive dysfunction in PD. Decreased rsFC between the SI and frontal area might be associated with early-onset MCI, suggesting that cholinergic deficits in the frontal brain areas might play an important role in the acceleration of cognitive decline in PD.<\/jats:p>","DOI":"10.1038\/s41598-017-02420-w","type":"journal-article","created":{"date-parts":[[2017,5,18]],"date-time":"2017-05-18T15:51:19Z","timestamp":1495122679000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Early-onset mild cognitive impairment in Parkinson\u2019s disease: Altered corticopetal cholinergic network"],"prefix":"10.1038","volume":"7","author":[{"given":"Injoong","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na-Young","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Yunjin Bak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phil","family":"Hyu Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung-Koo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo","family":"Mee Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,5,24]]},"reference":[{"key":"2420_CR1","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1146\/annurev-pathol-011110-130242","volume":"6","author":"JM Shulman","year":"2011","unstructured":"Shulman, J. M., De Jager, P. L. & Feany, M. B. Parkinson\u2019s disease: genetics and pathogenesis. Annual review of pathology \n                           6, 193\u2013222, doi:10.1146\/annurev-pathol-011110-130242 (2011).","journal-title":"Annual review of pathology"},{"key":"2420_CR2","doi-asserted-by":"publisher","unstructured":"Emre, M. et al. Clinical diagnostic criteria for dementia associated with Parkinson\u2019s disease. Mov Disord \n                           22, 1689\u20131707, quiz 1837, doi:10.1002\/mds.21507 (2007).","DOI":"10.1002\/mds.21507"},{"key":"2420_CR3","doi-asserted-by":"publisher","first-page":"1814","DOI":"10.1002\/mds.23823","volume":"26","author":"I Litvan","year":"2011","unstructured":"Litvan, I. et al. MDS Task Force on mild cognitive impairment in Parkinson\u2019s disease: critical review of PD-MCI. Mov Disord \n                           26, 1814\u20131824, doi:10.1002\/mds.23823 (2011).","journal-title":"Mov Disord"},{"key":"2420_CR4","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1136\/jnnp.48.5.413","volume":"48","author":"EK Perry","year":"1985","unstructured":"Perry, E. K. et al. Cholinergic correlates of cognitive impairment in Parkinson\u2019s disease: comparisons with Alzheimer\u2019s disease. J Neurol Neurosurg Psychiatry \n                           48, 413\u2013421, doi:10.1136\/jnnp.48.5.413 (1985).","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2420_CR5","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.1016\/j.neurobiolaging.2010.11.015","volume":"33","author":"SH Choi","year":"2012","unstructured":"Choi, S. H. et al. Volumetric analysis of the substantia innominata in patients with Parkinson\u2019s disease according to cognitive status. Neurobiology of aging \n                           33, 1265\u20131272, doi:10.1016\/j.neurobiolaging.2010.11.015 (2012).","journal-title":"Neurobiology of aging"},{"key":"2420_CR6","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1212\/WNL.0b013e3181ab2b58","volume":"73","author":"H Shimada","year":"2009","unstructured":"Shimada, H. et al. Mapping of brain acetylcholinesterase alterations in Lewy body disease by PET. Neurology \n                           73, 273\u2013278, doi:10.1212\/WNL.0b013e3181ab2b58 (2009).","journal-title":"Neurology"},{"key":"2420_CR7","doi-asserted-by":"publisher","first-page":"1716","DOI":"10.1212\/01.wnl.0000191154.78131.f6","volume":"65","author":"R Hilker","year":"2005","unstructured":"Hilker, R. et al. Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathways. Neurology \n                           65, 1716\u20131722, doi:10.1212\/01.wnl.0000191154.78131.f6 (2005).","journal-title":"Neurology"},{"key":"2420_CR8","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.1093\/brain\/awr031","volume":"134","author":"Y Compta","year":"2011","unstructured":"Compta, Y. et al. Lewy- and Alzheimer-type pathologies in Parkinson\u2019s disease dementia: which is more important? Brain \n                           134, 1493\u20131505, doi:10.1093\/brain\/awr031 (2011).","journal-title":"Brain"},{"key":"2420_CR9","doi-asserted-by":"publisher","first-page":"1931","DOI":"10.1212\/01.wnl.0000249130.63615.cc","volume":"67","author":"C Ballard","year":"2006","unstructured":"Ballard, C. et al. Differences in neuropathologic characteristics across the Lewy body dementia spectrum. Neurology \n                           67, 1931\u20131934, doi:10.1212\/01.wnl.0000249130.63615.cc (2006).","journal-title":"Neurology"},{"key":"2420_CR10","doi-asserted-by":"publisher","first-page":"2356","DOI":"10.1093\/brain\/awu159","volume":"137","author":"R Gonzalez-Redondo","year":"2014","unstructured":"Gonzalez-Redondo, R. et al. Grey matter hypometabolism and atrophy in Parkinson\u2019s disease with cognitive impairment: a two-step process. Brain \n                           137, 2356\u20132367, doi:10.1093\/brain\/awu159 (2014).","journal-title":"Brain"},{"key":"2420_CR11","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1016\/j.neuroimage.2006.09.003","volume":"34","author":"C Huang","year":"2007","unstructured":"Huang, C. et al. Metabolic brain networks associated with cognitive function in Parkinson\u2019s disease. Neuroimage \n                           34, 714\u2013723, doi:10.1016\/j.neuroimage.2006.09.003 (2007).","journal-title":"Neuroimage"},{"key":"2420_CR12","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1007\/PL00007725","volume":"244","author":"B Dubois","year":"1997","unstructured":"Dubois, B. & Pillon, B. Cognitive deficits in Parkinson\u2019s disease. J Neurol \n                           244, 2\u20138, doi:10.1007\/PL00007725 (1997).","journal-title":"J Neurol"},{"key":"2420_CR13","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1007\/s00415-005-0971-0","volume":"253","author":"NI Bohnen","year":"2006","unstructured":"Bohnen, N. I. et al. Cognitive correlates of cortical cholinergic denervation in Parkinson\u2019s disease and parkinsonian dementia. J Neurol \n                           253, 242\u2013247, doi:10.1007\/s00415-005-0971-0 (2006).","journal-title":"J Neurol"},{"key":"2420_CR14","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1093\/brain\/awv104","volume":"138","author":"J Gratwicke","year":"2015","unstructured":"Gratwicke, J., Jahanshahi, M. & Foltynie, T. Parkinson\u2019s disease dementia: a neural networks perspective. Brain \n                           138, 1454\u20131476, doi:10.1093\/brain\/awv104 (2015).","journal-title":"Brain"},{"key":"2420_CR15","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/0006-8993(86)91401-0","volume":"362","author":"M Ruberg","year":"1986","unstructured":"Ruberg, M., Rieger, F., Villageois, A., Bonnet, A. M. & Agid, Y. Acetylcholinesterase and butyrylcholinesterase in frontal cortex and cerebrospinal fluid of demented and non-demented patients with Parkinson\u2019s disease. Brain Res \n                           362, 83\u201391, doi:10.1016\/0006-8993(86)91401-0 (1986).","journal-title":"Brain Res"},{"key":"2420_CR16","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1093\/brain\/awm111","volume":"130","author":"CH Williams-Gray","year":"2007","unstructured":"Williams-Gray, C. H., Foltynie, T., Brayne, C. E., Robbins, T. W. & Barker, R. A. Evolution of cognitive dysfunction in an incident Parkinson\u2019s disease cohort. Brain \n                           130, 1787\u20131798, doi:10.1093\/brain\/awm111 (2007).","journal-title":"Brain"},{"key":"2420_CR17","doi-asserted-by":"publisher","first-page":"2958","DOI":"10.1093\/brain\/awp245","volume":"132","author":"CH Williams-Gray","year":"2009","unstructured":"Williams-Gray, C. H. et al. The distinct cognitive syndromes of Parkinson\u2019s disease: 5 year follow-up of the CamPaIGN cohort. Brain \n                           132, 2958\u20132969, doi:10.1093\/brain\/awp245 (2009).","journal-title":"Brain"},{"key":"2420_CR18","doi-asserted-by":"publisher","first-page":"848","DOI":"10.2967\/jnumed.111.089946","volume":"52","author":"NI Bohnen","year":"2011","unstructured":"Bohnen, N. I. et al. Cerebral glucose metabolic features of Parkinson disease and incident dementia: longitudinal study. J Nucl Med \n                           52, 848\u2013855, doi:10.2967\/jnumed.111.089946 (2011).","journal-title":"J Nucl Med"},{"key":"2420_CR19","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.1002\/mds.22560","volume":"24","author":"JB Pereira","year":"2009","unstructured":"Pereira, J. B. et al. Neuroanatomical substrate of visuospatial and visuoperceptual impairment in Parkinson\u2019s disease. Mov Disord \n                           24, 1193\u20131199, doi:10.1002\/mds.22560 (2009).","journal-title":"Mov Disord"},{"key":"2420_CR20","doi-asserted-by":"publisher","first-page":"1716","DOI":"10.1212\/01.wnl.0000191154.78131.f6","volume":"65","author":"R Hilker","year":"2005","unstructured":"Hilker, R. et al. Dementia in Parkinson disease functional imaging of cholinergic and dopaminergic pathways. Neurology \n                           65, 1716\u20131722, doi:10.1212\/01.wnl.0000191154.78131.f6 (2005).","journal-title":"Neurology"},{"key":"2420_CR21","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1002\/hbm.22622","volume":"36","author":"HC Baggio","year":"2015","unstructured":"Baggio, H. C. et al. Cognitive impairment and resting-state network connectivity in Parkinson\u2019s disease. Human brain mapping \n                           36, 199\u2013212, doi:10.1002\/hbm.22622 (2015).","journal-title":"Human brain mapping"},{"key":"2420_CR22","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/j.neuroimage.2014.04.019","volume":"97","author":"CS Li","year":"2014","unstructured":"Li, C. S. et al. Resting state functional connectivity of the basal nucleus of Meynert in humans: in comparison to the ventral striatum and the effects of age. Neuroimage \n                           97, 321\u2013332, doi:10.1016\/j.neuroimage.2014.04.019 (2014).","journal-title":"Neuroimage"},{"key":"2420_CR23","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1159\/000341998","volume":"11","author":"AA Kehagia","year":"2013","unstructured":"Kehagia, A. A., Barker, R. A. & Robbins, T. W. Cognitive impairment in Parkinson\u2019s disease: the dual syndrome hypothesis. Neuro-degenerative diseases \n                           11, 79\u201392, doi:10.1159\/000341998 (2013).","journal-title":"Neuro-degenerative diseases"},{"key":"2420_CR24","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1038\/nrneurol.2017.27","volume":"13","author":"D Aarsland","year":"2017","unstructured":"Aarsland, D. et al. Cognitive decline in Parkinson disease. Nature reviews. Neurology \n                           13, 217\u2013231, doi:10.1038\/nrneurol.2017.27 (2017).","journal-title":"Nature reviews. Neurology"},{"key":"2420_CR25","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.neuropsychologia.2015.07.031","volume":"77","author":"SJ Fallon","year":"2015","unstructured":"Fallon, S. J. et al. Differential optimal dopamine levels for set-shifting and working memory in Parkinson\u2019s disease. Neuropsychologia \n                           77, 42\u201351, doi:10.1016\/j.neuropsychologia.2015.07.031 (2015).","journal-title":"Neuropsychologia"},{"key":"2420_CR26","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1136\/jnnp-2013-305062","volume":"85","author":"JE Lee","year":"2014","unstructured":"Lee, J. E. et al. Exploratory analysis of neuropsychological and neuroanatomical correlates of progressive mild cognitive impairment in Parkinson\u2019s disease. J Neurol Neurosurg Psychiatry \n                           85, 7\u201316, doi:10.1136\/jnnp-2013-305062 (2014).","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2420_CR27","doi-asserted-by":"publisher","first-page":"897","DOI":"10.3174\/ajnr.A4626","volume":"37","author":"NY Shin","year":"2016","unstructured":"Shin, N. Y. et al. Different Functional and Microstructural Changes Depending on Duration of Mild Cognitive Impairment in Parkinson Disease. AJNR. American journal of neuroradiology \n                           37, 897\u2013903, doi:10.3174\/ajnr.A4626 (2016).","journal-title":"AJNR. American journal of neuroradiology"},{"key":"2420_CR28","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.neuron.2009.03.024","volume":"62","author":"WW Seeley","year":"2009","unstructured":"Seeley, W. W., Crawford, R. K., Zhou, J., Miller, B. L. & Greicius, M. D. Neurodegenerative diseases target large-scale human brain networks. Neuron \n                           62, 42\u201352, doi:10.1016\/j.neuron.2009.03.024 (2009).","journal-title":"Neuron"},{"key":"2420_CR29","doi-asserted-by":"publisher","first-page":"3067","DOI":"10.1007\/s00429-015-1087-7","volume":"221","author":"D Shah","year":"2016","unstructured":"Shah, D. et al. Cholinergic and serotonergic modulations differentially affect large-scale functional networks in the mouse brain. Brain structure & function \n                           221, 3067\u20133079, doi:10.1007\/s00429-015-1087-7 (2016).","journal-title":"Brain structure & function"},{"key":"2420_CR30","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s00213-011-2221-8","volume":"216","author":"J Tanabe","year":"2011","unstructured":"Tanabe, J. et al. Nicotine effects on default mode network during resting state. Psychopharmacology \n                           216, 287\u2013295, doi:10.1007\/s00213-011-2221-8 (2011).","journal-title":"Psychopharmacology"},{"key":"2420_CR31","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1212\/WNL.0000000000002839","volume":"87","author":"SJ Colloby","year":"2016","unstructured":"Colloby, S. J. et al. Cholinergic and perfusion brain networks in Parkinson disease dementia. Neurology \n                           87, 178\u2013185, doi:10.1212\/WNL.0000000000002839 (2016).","journal-title":"Neurology"},{"key":"2420_CR32","doi-asserted-by":"publisher","first-page":"8890","DOI":"10.1523\/JNEUROSCI.5698-11.2012","volume":"32","author":"MR Brier","year":"2012","unstructured":"Brier, M. R. et al. Loss of intranetwork and internetwork resting state functional connections with Alzheimer\u2019s disease progression. The Journal of neuroscience: the official journal of the Society for Neuroscience \n                           32, 8890\u20138899, doi:10.1523\/JNEUROSCI.5698-11.2012 (2012).","journal-title":"The Journal of neuroscience: the official journal of the Society for Neuroscience"},{"key":"2420_CR33","doi-asserted-by":"publisher","first-page":"457","DOI":"10.3233\/JAD-142547","volume":"45","author":"S Gardini","year":"2015","unstructured":"Gardini, S. et al. Increased functional connectivity in the default mode network in mild cognitive impairment: a maladaptive compensatory mechanism associated with poor semantic memory performance. Journal of Alzheimer\u2019s disease: JAD \n                           45, 457\u2013470, doi:10.3233\/JAD-142547 (2015).","journal-title":"Journal of Alzheimer\u2019s disease: JAD"},{"key":"2420_CR34","doi-asserted-by":"publisher","first-page":"4124","DOI":"10.1002\/cne.23415","volume":"521","author":"MM Mesulam","year":"2013","unstructured":"Mesulam, M. M. Cholinergic circuitry of the human nucleus basalis and its fate in Alzheimer\u2019s disease. The Journal of comparative neurology \n                           521, 4124\u20134144, doi:10.1002\/cne.23415 (2013).","journal-title":"The Journal of comparative neurology"},{"key":"2420_CR35","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1016\/0306-4522(84)90083-6","volume":"13","author":"DB Rye","year":"1984","unstructured":"Rye, D. B., Wainer, B. H., Mesulam, M. M., Mufson, E. J. & Saper, C. B. Cortical projections arising from the basal forebrain: a study of cholinergic and noncholinergic components employing combined retrograde tracing and immunohistochemical localization of choline acetyltransferase. Neuroscience \n                           13, 627\u2013643, doi:10.1016\/0306-4522(84)90083-6 (1984).","journal-title":"Neuroscience"},{"key":"2420_CR36","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","volume":"55","author":"AJ Hughes","year":"1992","unstructured":"Hughes, A. J., Daniel, S. E., Kilford, L. & Lees, A. J. Accuracy of clinical diagnosis of idiopathic Parkinson\u2019s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry \n                           55, 181\u2013184, doi:10.1136\/jnnp.55.3.181 (1992).","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2420_CR37","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1001\/archpsyc.1961.01710120031004","volume":"4","author":"AT Beck","year":"1961","unstructured":"Beck, A. T., Ward, C. H., Mendelson, M., Mock, J. & Erbaugh, J. An inventory for measuring depression. Arch Gen Psychiatry \n                           4, 561\u2013571, doi:10.1001\/archpsyc.1961.01710120031004 (1961).","journal-title":"Arch Gen Psychiatry"},{"key":"2420_CR38","unstructured":"Kang, Y. & Na, D. L. Seoul Neuropsychological Screening Battery (Human Brain Research & Consulting Co., 2003)."},{"key":"2420_CR39","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1002\/mds.23477","volume":"26","author":"SK Song","year":"2011","unstructured":"Song, S. K. et al. The pattern of cortical atrophy in patients with Parkinson\u2019s disease according to cognitive status. Mov Disord \n                           26, 289\u2013296, doi:10.1002\/mds.23477 (2011).","journal-title":"Mov Disord"},{"key":"2420_CR40","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1076\/jcen.21.1.127.942","volume":"21","author":"H Kim","year":"1999","unstructured":"Kim, H. & Na, D. L. Normative data on the Korean version of the Boston Naming Test. J Clin Exp Neuropsychol \n                           21, 127\u2013133, doi:10.1076\/jcen.21.1.127.942 (1999).","journal-title":"J Clin Exp Neuropsychol"},{"key":"2420_CR41","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1002\/mds.24893","volume":"27","author":"I Litvan","year":"2012","unstructured":"Litvan, I. et al. Diagnostic criteria for mild cognitive impairment in Parkinson\u2019s disease: Movement Disorder Society Task Force guidelines. Mov Disord \n                           27, 349\u2013356, doi:10.1002\/mds.24893 (2012).","journal-title":"Mov Disord"},{"key":"2420_CR42","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1006\/nimg.1998.0396","volume":"9","author":"B Fischl","year":"1999","unstructured":"Fischl, B., Sereno, M. I. & Dale, A. M. Cortical surface-based analysis. II: Inflation, flattening, and a surface-based coordinate system. Neuroimage \n                           9, 195\u2013207, doi:10.1006\/nimg.1998.0396 (1999).","journal-title":"Neuroimage"},{"key":"2420_CR43","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1002\/(SICI)1097-0193(1999)8:4<272::AID-HBM10>3.0.CO;2-4","volume":"8","author":"B Fischl","year":"1999","unstructured":"Fischl, B., Sereno, M. I., Tootell, R. B. & Dale, A. M. High-resolution intersubject averaging and a coordinate system for the cortical surface. Human brain mapping \n                           8, 272\u2013284, doi:10.1002\/(SICI)1097-0193(1999)8:4<272::AID-HBM10>3.0.CO;2-4.","journal-title":"Human brain mapping"},{"key":"2420_CR44","doi-asserted-by":"publisher","first-page":"1756","DOI":"10.1016\/j.neurobiolaging.2009.11.006","volume":"32","author":"S George","year":"2011","unstructured":"George, S. et al. MRI-based volumetric measurement of the substantia innominata in amnestic MCI and mild AD. Neurobiology of aging \n                           32, 1756\u20131764, doi:10.1016\/j.neurobiolaging.2009.11.006 (2011).","journal-title":"Neurobiology of aging"},{"key":"2420_CR45","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/S0926-6410(03)00082-X","volume":"17","author":"SD Slotnick","year":"2003","unstructured":"Slotnick, S. D., Moo, L. R., Segal, J. B. & Hart, J. Jr. Distinct prefrontal cortex activity associated with item memory and source memory for visual shapes. Brain research. Cognitive brain research \n                           17, 75\u201382, doi:10.1016\/S0926-6410(03)00082-X (2003).","journal-title":"Brain research. Cognitive brain research"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-017-02420-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-017-02420-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-017-02420-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T04:36:05Z","timestamp":1671770165000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-017-02420-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,24]]},"references-count":45,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,12]]}},"alternative-id":["2420"],"URL":"https:\/\/doi.org\/10.1038\/s41598-017-02420-w","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,24]]},"assertion":[{"value":"17 January 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2017","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 May 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"2381"}}