{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:38:15Z","timestamp":1790617095518,"version":"4.1.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,7,21]],"date-time":"2017-07-21T00:00:00Z","timestamp":1500595200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2017,7,21]],"date-time":"2017-07-21T00:00:00Z","timestamp":1500595200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study aims to determine whether male sex has adverse effect on mortality and morbidities in very low birth weight infants (VLBWI) &lt;30 weeks of gestation and to ascertain this sex effect, stratified by gestational age, adjusting for perinatal risk factors. This is a population-based study from Korean Neonatal Network for VLBWI born at 23\n                    <jats:sup>+0<\/jats:sup>\n                    and 29\n                    <jats:sup>+6<\/jats:sup>\n                    weeks of gestation between January 2013 and December 2014. The primary outcome was gestation-specific sex difference in the occurrence of mortality, combined morbidities, and individual morbidity. A total of 2228 VLBWI were enrolled (males, 51.7%). Mortality was not different between sexes. The risk of bronchopulmonary dysplasia and combined morbidities was significantly higher in males \u226425 weeks of gestation (odds ratio [OR] 2.08, 95% confidence interval [CI] 1.35\u20133.20 and OR 2.00, CI 1.19\u20133.39, respectively). Males had a significantly higher incidence of periventricular leukomalacia at 23 and 29 weeks of gestation. The risk of severe retinopathy of prematurity was higher in females &gt;25 weeks of gestation. Although both sexes have similar risk for mortality, male sex remains an independent risk for major morbidities, especially at \u226425 weeks of gestation. The risk of each outcome for males has a specific pattern with increasing gestational age.\n                  <\/jats:p>","DOI":"10.1038\/s41598-017-06490-8","type":"journal-article","created":{"date-parts":[[2017,7,17]],"date-time":"2017-07-17T09:23:55Z","timestamp":1500283435000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Gestational age-specific sex difference in mortality and morbidities of preterm infants: A nationwide study"],"prefix":"10.1038","volume":"7","author":[{"given":"So-Yeon","family":"Shim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su Jin","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoung Ae","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1685-4276","authenticated-orcid":false,"given":"Eun Ae","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,7,21]]},"reference":[{"key":"6490_CR1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3109\/00016347709162009","volume":"56","author":"WHO","year":"1977","unstructured":"WHO. recommended definitions, terminology and format for statistical tables related to the perinatal period and use of a new certificate for cause of perinatal deaths. 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