{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T04:26:00Z","timestamp":1772079960420,"version":"3.50.1"},"reference-count":57,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T00:00:00Z","timestamp":1503532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T00:00:00Z","timestamp":1503532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Coral reefs are ecologically significant habitats. Coral-algal symbiosis confers ecological success on coral reefs and coral-microbial symbiosis is also vital to coral reefs. However, current understanding of coral-microbial symbiosis on a genomic scale is largely unknown. Here we report a potential microbial symbiont in corals revealed by metagenomics-based genomic study. Microbial cells in coral were enriched for metagenomic analysis and a high-quality draft genome of \u201c<jats:italic>Candidatus<\/jats:italic> Prosthecochloris korallensis\u201d was recovered by metagenome assembly and genome binning. Phylogenetic analysis shows \u201c<jats:italic>Ca<\/jats:italic>. P. korallensis\u201d belongs to the <jats:italic>Prosthecochloris<\/jats:italic> clade and is clustered with two <jats:italic>Prosthecochloris<\/jats:italic> clones derived from Caribbean corals. Genomic analysis reveals \u201c<jats:italic>Ca<\/jats:italic>. P. korallensis\u201d has potentially important ecological functions including anoxygenic photosynthesis, carbon fixation via the reductive tricarboxylic acid (rTCA) cycle, nitrogen fixation, and sulfur oxidization. Core metabolic pathway analysis suggests \u201c<jats:italic>Ca<\/jats:italic>. P. korallensis\u201d is a green sulfur bacterium capable of photoautotrophy or mixotrophy. Potential host-microbial interaction reveals a symbiotic relationship: \u201c<jats:italic>Ca<\/jats:italic>. P. korallensis\u201d might provide organic and nitrogenous nutrients to its host and detoxify sulfide for the host; the host might provide \u201c<jats:italic>Ca<\/jats:italic>. P. korallensis\u201d with an anaerobic environment for survival, carbon dioxide and acetate for growth, and hydrogen sulfide as an\u00a0electron donor for photosynthesis.<\/jats:p>","DOI":"10.1038\/s41598-017-09032-4","type":"journal-article","created":{"date-parts":[[2017,8,18]],"date-time":"2017-08-18T11:21:23Z","timestamp":1503055283000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Metagenomic analysis reveals a green sulfur bacterium as a potential coral symbiont"],"prefix":"10.1038","volume":"7","author":[{"given":"Lin","family":"Cai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guowei","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren-Mao","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haoya","family":"Tong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weipeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue Him","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James Y.","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1541-9627","authenticated-orcid":false,"given":"Jian-Wen","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei-Yuan","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,8,24]]},"reference":[{"key":"9032_CR1","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1126\/science.1085046","volume":"301","author":"TP Hughes","year":"2003","unstructured":"Hughes, T. 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Trends Microbiol \n                           23, 490\u2013497, doi:10.1016\/j.tim.2015.03.008 (2015).","journal-title":"Trends Microbiol"},{"key":"9032_CR6","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2012.2328","volume":"280","author":"CJ Krediet","year":"2013","unstructured":"Krediet, C. J., Ritchie, K. B., Paul, V. J. & Teplitski, M. Coral-associated micro-organisms and their roles in promoting coral health and thwarting diseases. P Roy Soc B-Biol Sci \n                           280, 20122328, doi:10.1098\/rspb.2012.2328 (2013).","journal-title":"P Roy Soc B-Biol Sci"},{"key":"9032_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3354\/meps243001","volume":"243","author":"F Rohwer","year":"2002","unstructured":"Rohwer, F., Seguritan, V., Azam, F. & Knowlton, N. Diversity and distribution of coral-associated bacteria. 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Photosynth Res \n                           104, 137\u2013152, doi:10.1007\/s11120-009-9515-2 (2010).","journal-title":"Photosynth Res"},{"key":"9032_CR14","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1007\/s00203-006-0102-z","volume":"185","author":"K Vogl","year":"2006","unstructured":"Vogl, K., Glaeser, J., Pfannes, K. R., Wanner, G. & Overmann, R. Chlorobium chlorochromatii sp nov., a symbiotic green sulfur bacterium isolated from the phototrophic consortium \u201cChlorochromatium aggregatum\u201d. Arch Microbiol \n                           185, 363\u2013372, doi:10.1007\/s00203-006-0102-z (2006).","journal-title":"Arch Microbiol"},{"key":"9032_CR15","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2013-14-11-r127","volume":"14","author":"ZF Liu","year":"2013","unstructured":"Liu, Z. F. et al. Genomic analysis reveals key aspects of prokaryotic symbiosis in the phototrophic consortium \u201cChlorochromatium aggregatum\u201d. 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