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Irrelevant disgust stimuli modulate moral judgments, with individual sensitivity determining the direction and size of effects across both hypothetical and incentive-compatible experimental designs. We investigated the neural circuitry underlying this modulation using fMRI in 19 individuals performing a moral judgment task with subliminal priming of disgust facial expressions. Our results indicate that individual changes in moral acceptability due to priming covaried with individual differences in activation within the dorsomedial prefrontal cortex (dmPFC). Further, whole-brain analyses identified changes in functional connectivity between the dmPFC and the temporal-parietal junction (TPJ). High sensitivity individuals showed enhanced functional connectivity between the TPJ and dmPFC, corresponding with deactivation in the dmPFC, and rating the moral dilemmas as more acceptable. Low sensitivity individuals showed the opposite pattern of results. Post-hoc, these findings replicated in the dorsal anterior cingulate cortex (daMCC), an adjacent region implicated in converting between objective and subjective valuation. This suggests a specific computational mechanism \u2013 that disgust stimuli modulate moral judgments by altering the integration of social information to determine the subjective valuation of the considered moral actions.<\/jats:p>","DOI":"10.1038\/s41598-017-11147-7","type":"journal-article","created":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T13:49:58Z","timestamp":1504273798000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Moral judgment modulation by disgust priming via altered fronto-temporal functional connectivity"],"prefix":"10.1038","volume":"7","author":[{"given":"Julian","family":"Lim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoanna A.","family":"Kurnianingsih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"How Hwee","family":"Ong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5585-2978","authenticated-orcid":false,"given":"O\u2019Dhaniel A.","family":"Mullette-Gillman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,9,7]]},"reference":[{"key":"11147_CR1","doi-asserted-by":"publisher","first-page":"1100","DOI":"10.1037\/a0030503","volume":"142","author":"HA Chapman","year":"2013","unstructured":"Chapman, H. 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