{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:26:45Z","timestamp":1791358005532,"version":"4.3.1"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,9,12]],"date-time":"2017-09-12T00:00:00Z","timestamp":1505174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2017,9,12]],"date-time":"2017-09-12T00:00:00Z","timestamp":1505174400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study was aimed to evaluate visual performance at near to far distances in early presbyopic patients undergoing monovision by implantation of an ICL with a central hole (hole ICL). This pilot study comprised thirty-four eyes of 17 early presbyopic patients (age, 40 to 53 years) who underwent hole ICL implantation, and whose targeted refraction was set at emmetropia for the dominant eye, and at slight myopia (\u22120.5 to \u22121.0 diopters (D)) for the non-dominant eye. Corrected distance visual acuity was significantly improved, from \u22120.11\u2009\u00b1\u20090.07 preoperatively to \u22120.19\u2009\u00b1\u20090.09 logMAR postoperatively (p\u2009&lt;\u20090.001, Wilcoxon signed-rank test). Uncorrected distance visual acuity was also significantly improved from 1.43\u2009\u00b1\u20090.35 preoperatively to \u22120.04\u2009\u00b1\u20090.18 logMAR postoperatively (p\u2009&lt;\u20090.001). The mean binocular visual acuity was 0.01 logMAR or better at all distances (5.0, 3.0, 2.0, 1.0, 0.7, 0.5, and 0.3\u2009m). All eyes were within\u2009\u00b1\u20090.5 D of the targeted correction. All patients had within the normal range of near stereopsis. Neither cataract formation, significant intraocular pressure rise, nor vision-threatening complications occurred. Monovision by hole ICL implantation provided good binocular vision at near to far distances, without developing cataract, suggesting its feasibility as a new surgical presbyopic approach for early presbyopia.<\/jats:p>","DOI":"10.1038\/s41598-017-11539-9","type":"journal-article","created":{"date-parts":[[2017,9,6]],"date-time":"2017-09-06T22:00:32Z","timestamp":1504735232000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Monovision by Implantation of Posterior Chamber Phakic Intraocular Lens with a Central Hole (Hole ICL) for Early Presbyopia"],"prefix":"10.1038","volume":"7","author":[{"given":"Kazutaka","family":"Kamiya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahide","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natsumi","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3719-0376","authenticated-orcid":false,"given":"Nobuyuki","family":"Shoji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimiya","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,9,12]]},"reference":[{"key":"11539_CR1","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1001\/archophthalmol.2009.67","volume":"127","author":"K Kamiya","year":"2009","unstructured":"Kamiya, K., Shimizu, K., Igarashi, A., Hikita, F. & Komatsu, M. Four-year follow-up of posterior chamber phakic intraocular lens implantation for moderate to high myopia. Arch Ophthalmol. \n                           127, 845\u2013850 (2009).","journal-title":"Arch Ophthalmol."},{"key":"11539_CR2","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1016\/j.jcrs.2010.11.040","volume":"37","author":"JF Alfonso","year":"2011","unstructured":"Alfonso, J. F. et al. Posterior chamber collagen copolymer phakic intraocular lenses to correct myopia: five-year follow-up. J Cataract Refract Surg. \n                           37, 873\u2013880 (2011).","journal-title":"J Cataract Refract Surg."},{"key":"11539_CR3","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.ajo.2014.03.010","volume":"158","author":"K Kamiya","year":"2014","unstructured":"Kamiya, K., Shimizu, K., Igarashi, A. & Kobashi, H. Factors influencing long-term regression after posterior chamber phakic intraocular lens implantation for moderate to high myopia. Am J Ophthalmol. \n                           158, 179\u2013184 (2014).","journal-title":"Am J Ophthalmol."},{"key":"11539_CR4","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1016\/j.ajo.2013.11.006","volume":"157","author":"A Igarashi","year":"2014","unstructured":"Igarashi, A., Shimizu, K. & Kamiya, K. Eight-year follow-up of posterior chamber phakic intraocular lens implantation for moderate to high myopia. Am J Ophthalmol. \n                           157, 532\u2013539 (2014).","journal-title":"Am J Ophthalmol."},{"key":"11539_CR5","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1136\/bjophthalmol-2011-300148","volume":"96","author":"K Shimizu","year":"2012","unstructured":"Shimizu, K., Kamiya, K., Igarashi, A. & Shiratani, T. Early clinical outcomes of implantation of posterior chamber phakic intraocular lens with a central hole (Hole ICL) for moderate to high myopia. Br J Ophthalmol. \n                           96, 409\u2013412 (2012).","journal-title":"Br J Ophthalmol."},{"key":"11539_CR6","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/j.ajo.2012.04.001","volume":"154","author":"K Shimizu","year":"2012","unstructured":"Shimizu, K., Kamiya, K., Igarashi, A. & Shiratani, T. Intraindividual comparison of visual performance after posterior chamber phakic intraocular lens with and without a central hole implantation for moderate to high myopia. Am J Ophthalmol. \n                           154, 486\u2013494 (2012).","journal-title":"Am J Ophthalmol."},{"key":"11539_CR7","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003270","volume":"95","author":"K Shimizu","year":"2016","unstructured":"Shimizu, K., Kamiya, K., Igarashi, A. & Kobashi, H. Long-term Comparison of Posterior Chamber Phakic Intraocular Lens with and without a Central Hole (Hole ICL and Conventional ICL) Implantation for Moderate to High Myopia and Myopic Astigmatism: CONSORT-Compliant Article. Medicine (Baltimore). \n                           95, e3270 (2016).","journal-title":"Medicine (Baltimore)."},{"key":"11539_CR8","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1016\/S0886-3350(03)00065-8","volume":"29","author":"M Gonvers","year":"2003","unstructured":"Gonvers, M., Bornet, C. & Othenin-Girard, P. Implantable contact lens for moderate to high myopia: relationship of vaulting to cataract formation. J Cataract Refract Surg. \n                           29, 918\u2013924 (2003).","journal-title":"J Cataract Refract Surg."},{"key":"11539_CR9","doi-asserted-by":"publisher","first-page":"2269","DOI":"10.1016\/j.jcrs.2004.07.018","volume":"30","author":"B Lackner","year":"2004","unstructured":"Lackner, B. et al. Long-term results of implantation of phakic posterior chamber intraocular lenses. J Cataract Refract Surg. \n                           30, 2269\u20132276 (2004).","journal-title":"J Cataract Refract Surg."},{"key":"11539_CR10","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1016\/j.jcrs.2004.06.084","volume":"31","author":"AU Sarikkola","year":"2005","unstructured":"Sarikkola, A. U., Sen, H. N., Uusitalo, R. J. & Laatikainen, L. Traumatic cataract and other adverse events with the implantable contact lens. J Cataract Refract Surg. \n                           31, 511\u2013524 (2005).","journal-title":"J Cataract Refract Surg."},{"key":"11539_CR11","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1007\/s00417-006-0338-y","volume":"245","author":"K Fujisawa","year":"2007","unstructured":"Fujisawa, K. et al. Changes in the crystalline lens resulting from insertion of a phakic IOL (ICL) into the porcine eye. Graefes Arch Clin Exp Ophthalmol. \n                           245, 114\u2013122 (2007).","journal-title":"Graefes Arch Clin Exp Ophthalmol."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-017-11539-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-017-11539-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-017-11539-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T10:38:56Z","timestamp":1671791936000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-017-11539-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,12]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,12]]}},"alternative-id":["11539"],"URL":"https:\/\/doi.org\/10.1038\/s41598-017-11539-9","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,12]]},"assertion":[{"value":"14 March 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 August 2017","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 September 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Dr. Shimizu is a consultant of STAAR Surgical who has assisted with the development of patented technologies. The other authors have no competing interests as defined by Nature Publishing Group, or other interests that might be perceived to influence the results and\/or discussion reported in this paper.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"11302"}}