{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T23:12:55Z","timestamp":1793142775513,"version":"4.5.0"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,1,22]],"date-time":"2018-01-22T00:00:00Z","timestamp":1516579200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2018,1,22]],"date-time":"2018-01-22T00:00:00Z","timestamp":1516579200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This study was aimed to assess the predictability of intraocular lens (IOL) power calculation after cataract surgery for keratoconus. We retrospectively reviewed the clinical charts of 102 eyes of 71 consecutive keratoconic patients who developed cataract. We determined manifest spherical equivalent, prediction errors, and absolute errors, 1 month postoperatively. The achieved refraction was significantly more hyperopic than the targeted refraction, when keratometric readings were used (p\u2009=\u20090.001). At 1 month, 36% and 63% of the eyes were within \u00b10.5 and \u00b11.0 D, respectively, of the targeted correction. We found a significant correlation between the prediction error and the mean keratometry (Pearson correlation coefficient r\u2009=\u22120.545, p\u2009&lt;\u20090.001). No vision-threatening complications occurred in any case. The achieved refraction was significantly more myopic than the targeted refraction, when total corneal refractive power was used (p\u2009=\u20090.013). Phacoemulsification with IOL implantation appeared to be safe and effective, and the accuracy was also good in mild keratoconus, but not in severe keratoconus. It should be noted that that a large amount of hyperopic shift occurred especially in advanced keratoconic patients, when keratometric readings were used for IOL power calculation, and that a slight, but significant, myopic shift occurred, when total corneal refractive power was used.<\/jats:p>","DOI":"10.1038\/s41598-018-20040-w","type":"journal-article","created":{"date-parts":[[2018,1,16]],"date-time":"2018-01-16T06:12:55Z","timestamp":1516083175000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Predictability of Intraocular Lens Power Calculation for Cataract with Keratoconus: A Multicenter Study"],"prefix":"10.1038","volume":"8","author":[{"given":"Kazutaka","family":"Kamiya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Iijima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3719-0376","authenticated-orcid":false,"given":"Shoji","family":"Nobuyuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosai","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunori","family":"Miyata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takefumi","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Shimazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6509-9054","authenticated-orcid":false,"given":"Naoyuki","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,1,22]]},"reference":[{"key":"20040_CR1","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1016\/j.jcrs.2006.01.063","volume":"32","author":"A Leccisotti","year":"2006","unstructured":"Leccisotti, A. Refractive lens exchange in keratoconus. J Cataract Refract Surg. 32, 742\u2013746 (2006).","journal-title":"J Cataract Refract Surg."},{"key":"20040_CR2","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1097\/ICL.0b013e318030c96d","volume":"33","author":"N Thebpatiphat","year":"2007","unstructured":"Thebpatiphat, N., Hammersmith, K. M., Rapuano, C. J., Ayres, B. D. & Cohen, E. J. Cataract surgery in keratoconus. Eye Contact Lens. 33, 244\u2013246 (2007).","journal-title":"Eye Contact Lens."},{"key":"20040_CR3","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1136\/bjophthalmol-2013-303829","volume":"98","author":"MP Watson","year":"2014","unstructured":"Watson, M. P. et al. Cataract surgery outcome in eyes with keratoconus. Br J Ophthalmol. 98, 361\u2013364 (2014).","journal-title":"Br J Ophthalmol."},{"key":"20040_CR4","doi-asserted-by":"publisher","first-page":"2024","DOI":"10.1016\/j.jcrs.2009.05.043","volume":"35","author":"A Navas","year":"2009","unstructured":"Navas, A. & Su\u00e1rez, R. One-year follow-up of toric intraocular lens implantation in forme fruste keratoconus. J Cataract Refract Surg. 35, 2024\u20132027 (2009).","journal-title":"J Cataract Refract Surg."},{"key":"20040_CR5","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1097\/ICO.0b013e31820009d4","volume":"30","author":"N Visser","year":"2011","unstructured":"Visser, N., Gast, S. T., Bauer, N. J. & Nuijts, R. M. Cataract surgery with toric intraocular lens implantation in keratoconus: a case report. Cornea. 30, 720\u2013723 (2011).","journal-title":"Cornea."},{"key":"20040_CR6","doi-asserted-by":"publisher","first-page":"658","DOI":"10.3928\/1081597X-20110531-01","volume":"27","author":"M Jaimes","year":"2011","unstructured":"Jaimes, M. et al. Refractive lens exchange with toric intraocular lenses in keratoconus. J Refract Surg. 27, 658\u2013664 (2011).","journal-title":"J Refract Surg."},{"key":"20040_CR7","doi-asserted-by":"publisher","first-page":"884","DOI":"10.3928\/1081597X-20121106-02","volume":"28","author":"MA Nanavaty","year":"2012","unstructured":"Nanavaty, M. A., Lake, D. B. & Daya, S. M. Outcomes of pseudophakic toric intraocular lens implantation in keratoconic eyes with cataract. J Refract Surg. 28, 884\u2013889 (2012).","journal-title":"J Refract Surg."},{"key":"20040_CR8","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1136\/bjophthalmol-2013-303765","volume":"98","author":"JL Ali\u00f3","year":"2014","unstructured":"Ali\u00f3, J. L. et al. MICS with toric intraocular lenses in keratoconus: outcomes and predictability analysis of postoperative refraction. Br J Ophthalmol. 98, 365\u2013370 (2014).","journal-title":"Br J Ophthalmol."},{"key":"20040_CR9","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1097\/ICL.0000000000000136","volume":"41","author":"H Hashemi","year":"2015","unstructured":"Hashemi, H., Heidarian, S., Seyedian, M. A., Yekta, A. & Khabazkhoob, M. Evaluation of the results of using toric IOL in the cataract surgery of keratoconus patients. Eye Contact Lens. 41, 354\u2013358 (2015).","journal-title":"Eye Contact Lens."},{"key":"20040_CR10","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1007\/s10384-016-0449-x","volume":"60","author":"K Kamiya","year":"2016","unstructured":"Kamiya, K., Shimizu, K. & Miyake, T. Changes in astigmatism and corneal higher-order aberrations after phacoemulsification with toric intraocular lens implantation for mild keratoconus with cataract. 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Objective and subjective Outcome of clear lensectomy with toric IOL implantation after corneal collagen cross-linking in selected cases of keratoconus. Eye Contact Lens. 2016 Oct 3. [Epub ahead of print]."},{"key":"20040_CR14","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/S0039-6257(97)00119-7","volume":"42","author":"YS Rabinowitz","year":"1998","unstructured":"Rabinowitz, Y. S. Keratoconus. Surv Ophthalmol. 42, 297\u2013319 (1998).","journal-title":"Surv Ophthalmol."},{"key":"20040_CR15","doi-asserted-by":"publisher","first-page":"357","DOI":"10.3928\/1081597X-20090401-07","volume":"25","author":"JH Krumeich","year":"2009","unstructured":"Krumeich, J. H. & Kezirian, G. M. Circular keratotomy to reduce astigmatism and improve vision in stage I and II keratoconus. J Refract Surg. 25, 357\u2013365 (2009).","journal-title":"J Refract Surg."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-018-20040-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-018-20040-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-018-20040-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T20:12:12Z","timestamp":1671567132000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-018-20040-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,22]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,12]]}},"alternative-id":["20040"],"URL":"https:\/\/doi.org\/10.1038\/s41598-018-20040-w","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,22]]},"assertion":[{"value":"1 August 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 January 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"1312"}}