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Additionally,\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>jejuni<\/jats:italic>\n                    is the most common bacterial etiological agent in the autoimmune Guillain-Barr\u00e9 syndrome (GBS). Ganglioside mimicry by\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>jejuni<\/jats:italic>\n                    lipooligosaccharide (LOS) is the triggering factor of the disease. LOS-associated genes involved in the synthesis and transfer of sialic acid (glycosyltranferases belonging to family GT-42) are essential in\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>jejuni<\/jats:italic>\n                    to synthesize ganglioside-like LOS. Despite being isolated from GBS patients, scarce genetic evidence supports\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>coli<\/jats:italic>\n                    role in the disease. In this study, through data mining and bioinformatics analysis,\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>coli<\/jats:italic>\n                    is shown to possess a larger GT-42 glycosyltransferase repertoire than\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>jejuni<\/jats:italic>\n                    . Although GT-42 glycosyltransferases are widely distributed in\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>coli<\/jats:italic>\n                    population, only a fraction of\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>coli<\/jats:italic>\n                    strains (1%) are very likely able to express ganglioside mimics. Even though the activity of\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>coli<\/jats:italic>\n                    specific GT-42 enzymes and their role in shaping the bacterial population are yet to be explored, evidence presented herein suggest that loss of function of some LOS-associated genes occurred during agriculture niche adaptation.\n                  <\/jats:p>","DOI":"10.1038\/s41598-018-21438-2","type":"journal-article","created":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T07:35:13Z","timestamp":1518075313000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Origin, evolution, and distribution of the molecular machinery for biosynthesis of sialylated lipooligosaccharide structures in Campylobacter coli"],"prefix":"10.1038","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9716-8154","authenticated-orcid":false,"given":"Alejandra","family":"Culebro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel P.","family":"Machado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5274-2722","authenticated-orcid":false,"given":"Jo\u00e3o Andr\u00e9","family":"Carri\u00e7o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirko","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,2,14]]},"reference":[{"key":"21438_CR1","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1111\/1574-6976.12056","volume":"38","author":"BF Cress","year":"2014","unstructured":"Cress, B. 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